Evaluating the implantation of an inflatable penile prosthesis and vacuum therapy for men with Peyronie’s disease

This study aimed to investigate the efficacy and satisfaction rate of an inflatable penile prosthesis (IPP) to treat erectile dysfunction (ED) in men with Peyronie's disease (PD). This study found that patients with PD and ED can safely and effectively have an IPP placed.

Peyronie's disease (PD) is a condition of the penis caused by scar tissue, called plaque. This plaque forms inside the penis. It can result in a bent, rather than straight, erect penis. Most men with PD can still have sex. But for some, it can be painful and can cause erectile dysfunction (ED).

One option to treat these men is to surgically remove the plaques. For the treatment of ED, an inflatable penile prosthesis (IPP) can be implanted. This is a device that can be inflated to create an erection. To keep the penis from bending after surgery, they can use a vacuum device 3 minutes 2 times a day. The safety and effectiveness of all these procedures in patients with PD and ED remain under investigation. 

This study included 145 men with PD. They all had IPP placements. Men completed questionnaires at the beginning of the study and then a year after surgery to evaluate patients' satisfaction.

93.7% of patients had achieved a normally curved penis. After 6 months and 1 year after surgery, erectile function significantly improved. Side-effects reported were a mechanical failure of the IPP (2% of patients) and worsening of the ED in 1.3% of patients. 

This study found that patients with PD and ED can safely and effectively have an IPP placed.

There was no group for comparison. Further randomized studies are needed for confirmation of the results.