In a nutshell This study evaluated whether the risk and severity of asparaginase-associated pancreatitis (AAP) depend on the age of patients with acute lymphoblastic leukemia (ALL). The main finding was that the AAP risk was higher in adolescents and adults compared to younger children. Some background Asparaginase (ASP; Oncaspar) is an important...
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Evaluating outcomes of immunotherapy for melanoma before and after surgery
In a nutshell This study wanted to find out what the best order is for treating melanoma with immunotherapy medications and surgery. The study found that immunotherapy before surgery resulted in better survival outcomes for these patients. Some background Treatments for melanoma have changed in the last few years. A newer treatment is...
Read MorePhysiotherapy combined with auditory cues improves balance in patients with Parkinson’s disease
In a nutshell This study investigated the effectiveness of balance training with and without auditory cues (AC) in Parkinson's disease (PD). Researchers suggested that balance training with AC improves the effectiveness of treatment. Some background Parkinson's disease (PD) is a chronic disease of the brain. Brain cells are affected and...
Read MoreDoes laparoscopic surgery decrease complications after colorectal cancer surgery?
In a nutshell This study investigated if laparoscopic surgery (LS) is associated with fewer complications in colorectal cancer compared to classic, open surgery. Researchers suggested that LS decreases the odds of having a complication after colorectal cancer surgery. Some background Colorectal cancer is one of the most common cancer...
Read MoreGabapentin and pregabalin for hot flushes in women with breast cancer receiving hormonal therapy
In a nutshell This study wanted to find out if two medications, gabapentin (Neurontin) and pregabalin (Lyrica) helped relieve symptoms of hot flushes and night sweats in postmenopausal women and women with breast cancer receiving hormonal therapy. The study found that gabapentin reduced the frequency of hot flushes in these women. Some background...
Read MoreMetastasis surgery improves survival of patients with advanced colorectal cancer
In a nutshell This study investigated the survival outcomes of patients who underwent surgery for colorectal cancer (CRC) metastasis (spread to other parts of the body). Researchers suggested that metastasis surgery is associated with survival improvement in these patients. Some background CRC is one of the most common cancers worldwide. A...
Read MoreDoes FSH supplementation improve male fertility?
In a nutshell This study investigated if follicle-stimulating hormone (FSH) supplementation improves sperm parameters in male infertility (MI). They found that FSH improved sperm parameters in these patients. Some background Male infertility (MI) is a common cause of infertility. In many cases, the cause of MI cannot be explained. MI...
Read MoreAge and infertility treatment – do women with polycystic ovarian syndrome have an advantage?
In a nutshell This study investigated the effect of age on infertility treatment in women with polycystic ovarian syndrome (PCOS). They found that age-related decline (ARD) in fertility treatment outcomes was slower in women with PCOS. Some background Polycystic ovarian syndrome (PCOS) is caused by cysts on the ovaries. Women with PCOS have...
Read MoreEvaluating acalabrutinib plus obinutuzumab in patients with chronic lymphocytic leukemia
In a nutshell This study evaluated the safety and effectiveness of the combination of acalabrutinib (Calquence) and obinutuzumab (Gazyva) in patients with chronic lymphocytic leukemia (CLL). The authors concluded that this combination was effective and well tolerated in patients with CLL. Some background Chronic lymphocytic leukemia (CLL) is a cancer...
Read MoreAsciminib as a treatment option for patients with chronic myeloid leukemia after kinase inhibitor failure
In a nutshell This study aimed to investigate if asciminib was effective in patients with chronic myeloid leukemia who had resistance or unacceptable side effects to other tyrosine kinase inhibitors. This study concluded that asciminib showed promise in these patients. Some background Asciminib is a...
Read MoreDecitabine compared to standard treatment in older patients with acute myeloid leukemia
In a nutshell This study aimed to investigate the safety and effectiveness of decitabine in older patients with acute myeloid leukemia. This study concluded that decitabine is safe and effective in these patients. Some background The occurrence of acute myeloid leukemia (AML) increases with age. The overall prognosis...
Read MoreExtracorporeal shock wave therapy improves outcomes of stroke survivors
In a nutshell This study investigated the long-term effects of extracorporeal shock wave therapy (ESWT) in the treatment of stroke survivors. Researchers suggested that ESWT is associated with improved outcomes in these patients. Some background A stroke happens when blood flow to the brain is cut-off. Brain cells stop receiving oxygen and begin to...
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