In a nutshell This study assessed the link between metformin (Glucophage) use in hospitalized and non-hospitalized patients with diabetes and different outcomes due to coronavirus disease 2019 (COVID-19). The study showed that metformin use was associated with a protective effect in COVID-19 outcomes in patients with type 2 diabetes (T2D). Some...
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In a nutshell This study analyzed the impact of cognitive-motor dual-task training (CMDT) on patients with chronic stroke. The authors concluded that CMDT had beneficial effects on balance ability, gait, and upper limb function in patients with chronic stroke. Some background A stroke involves an interruption or slowing of blood flow and oxygen to the...
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In a nutshell This study evaluated the long-term relationship between bariatric surgery (BS; weight loss surgery) and major adverse cardiovascular events (MACE) in patients with obesity, diabetes, and hypertension (high blood pressure; BP). The study showed that a sustained decrease in MACE occurrence was associated with BS in...
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In a nutshell This study evaluated the long-term relationship between bariatric surgery (BS; weight loss surgery) and major adverse cardiovascular events (MACE) in patients with obesity, diabetes, and hypertension (high blood pressure; BP). The study showed that a sustained decrease in MACE occurrence was associated with BS in these patients. Some...
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In a nutshell This study evaluated the effectiveness and safety of an all-oral combination of ixazomib (Ninlaro), lenalidomide (Revlimid), and dexamethasone (Decadron) in transplant-eligible patients with newly diagnosed multiple myeloma (MM). The data showed that this combination was effective with manageable side effects in these...
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In a nutshell This study reported the long-term effectiveness and safety of adding carboplatin (Paraplatin) with or without veliparib (ABT-888) to standard chemotherapy given before surgery (neoadjuvant chemotherapy; NACT) in patients with early-stage triple-negative breast cancer (TNBC). The data showed that the addition of carboplatin to standard NACT...
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In a nutshell This study evaluated the effects of using regular acetaminophen (Paracetamol) on blood pressure (BP) in patients with hypertension (high BP). The data showed that regular daily acetaminophen use increased BP in these patients and increased the risk of cardiovascular disease when compared with placebo. Some background Hypertension or high...
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In a nutshell This study investigated the benefit of frequent surveillance imaging on the survival outcomes in patients with resected stage III melanoma. The data showed that patients who underwent less frequent imaging (12-monthly) had better outcomes than those who underwent more frequent imaging (3- to 4-monthly). Some background Melanoma is a...
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In a nutshell This study evaluated the effect of whole grain consumption in glycaemic (blood sugar) control of patients with diabetes. The data showed that whole grain consumption was beneficial for the control of blood glucose levels in these patients. Some background Diabetes is a condition in which patients have high blood sugar (glucose) levels...
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In a nutshell This study evaluated the long-term effects of exercise and regular physical activity in patients with early Parkinson’s disease (PD). The data showed that in the long-term, the maintenance of high regular physical activity levels and exercise habits were strongly associated with better clinical outcomes of PD symptoms. Some...
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In a nutshell This study investigated if de-escalation (reducing the intensity) of dual antiplatelet therapy (DAPT) with clopidogrel (Plavix) might be better than ticagrelor (Brilique)-based antiplatelet therapy in stabilized patients with acute myocardial infarction (MI; heart attack) undergoing percutaneous coronary intervention (PCI). The data...
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In a nutshell This study evaluated the safety and effectiveness of pembrolizumab (Keytruda) in combination with rituximab (Rituxan) in patients with relapsed or refractory (r/r) follicular lymphoma (FL). The data showed that pembrolizumab in combination with rituximab was safe and effective in these patients. Some background Follicular lymphoma (FL)...
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