In a nutshell This study compared the safety of two hormonal medications used to treat breast cancer, tamoxifen (Nolvadex) and letrozole (Femara). This study found that tamoxifen was associated with an increased risk of blood clots, while letrozole was associated with an increased risk of angina and heart attacks. Some background Hormone-positive...
Read More
In a nutshell This study investigated whether probiotics (PBs) improve constipation in patients with Parkinson's disease (PD). Researchers suggested that PBs treatment improves constipation in these patients. Some background PD is a chronic disease that affects the brain. These cells lose their ability to control body functions leaving patients...
Read More
In a nutshell This study aimed to compare autologous stem cell transplant (ASCT) and conventional chemotherapy (CT) as second-line treatments in patients with relapsed early-stage (ES), classical Hodgkin lymphoma (cHL). This study concluded that CT treatments may be a suitable second-line treatment option for patients...
Read More
In a nutshell This study aimed to investigate the safety and effectiveness of the combination of ivosidenib (Tibsovo) and azacitidine (Vidaza) in patients with acute myeloid leukemia (AML) with isocitrate dehydrogenase 1 (IDH1) mutation (permanent change). This study concluded that this combination was well tolerated and...
Read More
In a nutshell This study compared the effectiveness of FOLFIRI (5-fluorouracil, folinic acid, and irinotecan) with either cetuximab (Erbitux) or bevacizumab (Avastin) in the treatment of advanced colorectal cancer (CRC). Researchers suggested that FOLFIRI with cetuximab resulted in improved response and longer survival for these patients. Some...
Read More
In a nutshell This study compared two cardiac rehab programs for patients with heart disease. One program is supervised in a hospital, while the other is done at home without supervision. They found that patients doing the rehab program at home started the program more quickly and had better outcomes. Some background After a heart attack or...
Read More
In a nutshell This study compared the effect of a conventional rehabilitation (CR) program to a home-based motor training rehabilitation (TR) program for patients with hemiplegia after stroke. The study showed that TR positively impacts movement function in the upper and lower extremities as well as skills...
Read More
In a nutshell This study investigated if lower limb robot training (LLRT) using the Hybrid Assistive Limb (HAL) device improves daily living in patients with stroke. Researchers suggested that HAL improves daily activities and walking ability in these patients. Some background A stroke consists of a blockage of the blood flow to the brain. This...
Read More
In a nutshell This study aimed to compare the effectiveness of acalabrutinib (Calquence) alone and in combination with obinutuzumab (Gazyva) to standard treatments for patients with chronic lymphocytic leukemia (CLL). This study concluded that acalabrutinib showed high effectiveness...
Read More
In a nutshell This study aimed to investigate if tazemetostat (Tazverik) was a safe and effective treatment in patients with relapsed/refractory follicular lymphoma (FL). This study concluded that tazemetostat provided durable responses and was well tolerated in these patients. Some background Tazemetostat is...
Read More
In a nutshell This study compared two treatments for lowering blood pressure (BP) in patients with high BP and chronic kidney disease (CKD). They found that there was no difference in the BP-lowering effect between the two drugs. Some background The kidneys are responsible for filtering water out of the blood and producing urine. The...
Read More
In a nutshell This study looked at the effects of two different diets on patients with heart disease. They found that compared to a low-fat diet, a Mediterranean diet leads to better recovery of the heart’s blood vessels. Some background Heart disease is a major cause of disability and death. Heart attacks are usually due to blockages...
Read More
