In a nutshell This study evaluated whether combining BRAF and MEK inhibitors was safer and more effective than BRAF inhibitor treatment alone for patients with melanoma. This study concluded that combination therapy led to better survival but was associated with certain side effects. Some background Melanoma is a type of skin cancer that can be...
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Evaluating risk of late versus early relapse for patients with diffuse large B-cell lymphoma
In a nutshell This study investigated the risk of relapse 5 years or more after treatment for patients with diffuse large B-cell lymphoma (DBLCL). This study concluded that the outcomes of patients with a late relapse were better than those in patients who relapsed early after treatment. Some background DLBCL is one of the most common types of...
Read MoreDecitabine, cytarabine and umbilical cord blood infusion as consolidation therapy for elderly patients with acute myeloid leukemia
In a nutshell This study aimed to investigate the combination of low-dose decitabine, medium-dose cytarabine and umbilical cord blood infusion as a consolidation therapy for elderly patients with acute myeloid leukemia. This study concluded that this treatment combination was effective in these patients. Some...
Read MoreInotuzumab ozogamicin treatment for patients with acute lymphoblastic leukemia and the burden of hospitalization
In a nutshell This study aimed to investigate if treatment with inotuzumab ozogamicin in patients with relapsed/unresponsive acute lymphoblastic leukemia was associated with lower healthcare system burden compared to standard of care. This study...
Read MoreTotal testosterone density as a marker of tumor load in patients with prostate cancer
In a nutshell This study aimed to investigate a new way to evaluate prostate cancer risk, through the total testosterone density (TTD). This study found that TTD can be used to help manage patients with low-risk PCa. Some background Testosterone is a hormone that is made by the testicles. It usually fuels the growth of...
Read MoreMinimally invasive treatments for BPH-related lower urinary tract symptoms
In a nutshell This study aimed to evaluate a minimally invasive surgical treatment option for lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH). This study found that the temporary implantable nitinol device (iTIND) is a promising technique for these patients. Some background Benign prostatic...
Read MoreEvaluating the safety of re-treatment with radium-223
In a nutshell This study aimed to evaluate the safety and effectiveness of radium-223 (Xofigo, formerly known as Alpharadin) in patients with advanced prostate cancer that has spread to the bones and who have had this treatment previously. This study found that re-treatment with radium-223 was well tolerated and with good results. Some background...
Read MoreNivolumab in previously treated advanced non-small cell lung cancer – what is the long-term outlook for survival?
In a nutshell This study investigated survival rates in advanced non-small cell lung cancer (NSCLC) after nivolumab (Opdivo) treatment. They found that nivolumab was associated with longer survival time in patients that responded to treatment. Some background Lung cancer (LC) is one of the most common cancers worldwide. Non-small...
Read MoreSurviving cancer – is there a greater risk of cardiovascular disease long-term?
In a nutshell This study investigated if there is a higher risk of cardiovascular disease (CVD) in cancer survivors. They found that cancer survivors have a higher risk of CVD. Some background Improved cancer detection and treatment has increased the rates of survival. The number of cancer survivors living for more than 10 years is growing. Some...
Read MoreSurviving cancer – is there a greater risk of cardiovascular disease long-term?
In a nutshell This study investigated if there is a higher risk of cardiovascular disease (CVD) in cancer survivors. They found that cancer survivors have a higher risk of CVD. Some background Improved cancer detection and treatment has increased the rates of survival. The number of cancer survivors living for more than 10 years is growing. Some...
Read MoreSurviving cancer – is there a greater risk of cardiovascular disease long-term?
In a nutshell This study investigated if there is a higher risk of cardiovascular disease (CVD) in cancer survivors. They found that cancer survivors have a higher risk of CVD. Some background Improved cancer detection and treatment has increased the rates of survival. The number of cancer survivors living for more than 10 years is growing. Some...
Read MoreSurviving cancer – is there a greater risk of cardiovascular disease long-term?
In a nutshell This study investigated if there is a higher risk of cardiovascular disease (CVD) in cancer survivors. They found that cancer survivors have a higher risk of CVD. Some background Improved cancer detection and treatment has increased the rates of survival. The number of cancer survivors living for more than 10 years is growing. Some...
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