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Evaluating busulfan plus melphalan conditioning for patients with multiple myeloma before stem cell transplantation

Posted by on May 20, 2019 in Multiple Myeloma | 0 comments

In a nutshell This study evaluated the safety and effectiveness of busulfan (Myleran) plus melphalan (Alkeran) compared to melphalan alone for patients with multiple myeloma (MM) before autologous stem cell transplantation (ASCT). This study concluded that the combination treatment was more effective for these patients. Some background...

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Evaluating polatuzumab vedotin and pinatuzumab vedotin for relapsed or refractory NHL

Posted by on May 20, 2019 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This study evaluated the safety and effectiveness of rituximab (Rituxan) combined with either polatuzumab vedotin (pola) or pinatuzumab vedotin (pina) for patients with non-Hodgkin’s lymphoma (NHL) that has come back or stopped responding to treatment. This study concluded that pola was associated with better...

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PET scans in determining outcomes for patients with Hodgkin lymphoma treated with chemotherapy

Posted by on May 20, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study aimed to investigate the role of positron emission tomography (PET; an imaging technique) in determining the outcomes for patients with Hodgkin lymphoma treated with chemotherapy. This study concluded that negative-PET scans after chemotherapy predict good outcomes for these patients, regardless of stage at...

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Is Aquablation an effective treatment for urinary symptoms caused by an enlarged prostate?

Posted by on May 20, 2019 in Benign prostatic hyperplasia | 0 comments

In a nutshell The authors analyzed the effectiveness of Aquablation compared to other treatments for patients with urinary symptoms caused by an enlarged prostate. The authors concluded that Aquablation is probably as effective as transurethral resection of the prostate (TURP) in these patients. Some background An enlarged prostate may cause...

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Further surgery or non-surgical options for patients with remaining breast cancer after surgery

Posted by on May 19, 2019 in Breast cancer | 0 comments

In a nutshell This study evaluated whether treating breast cancer that has not been completely removed with more surgery was more effective than non-surgical options such as chemotherapy. This study found that there was no difference in outcomes between treating with further surgery versus treating with a non-surgical option. Some...

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Prostate cancer: can we predict recurrence?

Posted by on May 19, 2019 in Prostate cancer | 0 comments

In a nutshell This study examined the biochemical recurrence (BCR) of prostate cancer after minimally invasive prostate surgery. This study concluded the risk of BCR of prostate cancer decreases as the number of years after surgery without the disease increases.  Some background One treatment option for patients with prostate...

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High dose vitamin D supplementation may be associated with improved colorectal cancer outcomes

Posted by on May 19, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated if high-dose vitamin D combined with chemotherapy improves outcomes in patients with metastatic (spread to other parts of the body) colorectal cancer. Researchers suggested that high-dose vitamin D was associated with an improved chance of survival. Some background Vitamin D is associated with the intake of...

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Initial management with aflibercept, laser photocoagulation or observation in patients with diabetic eye disease?

Posted by on May 19, 2019 in Diabetes mellitus | 0 comments

In a nutshell This article investigated the rate of vision loss at 2 years among eyes with center involved-diabetic macular edema (CI-DME; vision loss in people with diabetes) initially managed with aflibercept (Eylea), laser photocoagulation (LP) or observation. The authors concluded that there was no significant difference in vision loss at 2...

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