In a nutshell This study explored the effects of different second-line therapies combined with metformin (Glucophage) in patients with type 2 diabetes (T2D). The data showed that metformin combinations with a sulfonylurea (SU) had the lowest weight loss, the smallest effect of lowering blood glucose, and an overall, reduced health...Read More
Diabetes mellitus Posts on Medivizor
In a nutshell This study looked at the use of citicoline and vitamin B12 eye drops (OMK2) to prevent diabetic retinopathy (DR; eye disease) in patients with type 1 diabetes (T1D). It found that using these drops for 36 months improved eye function tests. Some background Type 1 diabetes (T1D) is a common cause of blindness through...Read More
In a nutshell This study aimed to explore the effects of melatonin in addition to pregabalin (Lyrica) for the management of painful diabetic neuropathy (PDN). The authors concluded that melatonin added to pregabalin may help in reducing pain related to PDN in patients with type 2 diabetes (T2D). Some background...Read More
In a nutshell This study compared two heart interventions for people with coronary heart disease and type 2 diabetes (T2D). It found that coronary artery bypass grafting (CABG) led to better long-term outcomes than placing a stent in these patients. Some background Coronary heart disease (CHD) is a condition in which the arteries which supply blood to...Read More
In a nutshell This study evaluated the outcomes of cotadutide (MEDI0382) treatment in patients with type 2 diabetes (T2D) and obesity. This study concluded that cotadutide treatment improved glycemic (blood sugar) control and weight loss in these patients. Some background T2D is commonly associated with obesity. About 70% of patients with T2D...Read More
In a nutshell This study looked at the relationship between changes in the retinal nerves (diabetic retinopathy; DR) and changes in the nerves of the hands and feet (diabetic neuropathy; DN) in adolescents with type 1 diabetes (T1D). It found that tests that monitor the retinal nerves such as OCTA which is a quick and inexpensive test, could be...Read More
In a nutshell This study looked at remote screening for diabetic retinopathy (DR; eye disease) in a Japanese population. This study showed that remote screening for DR is an effective way of identifying patients who need ophthalmic intervention. Some background Long-term uncontrolled diabetes affects small blood vessels, including in the eyes....Read More
Are all glucagon-like peptide-1 receptor agonists equally safe and effective in patients with type 2 diabetes?
In a nutshell This study looked at 8 glucagon-like peptide-1 receptor agonists (GLP-1RAs) for the treatment of type 2 diabetes (T2D). They found that all 8 were more effective than placebo and there were no significant differences in safety. Some background GLP-1RA is a type of diabetic medication that works by increasing natural...Read More
Effect of pioglitazone treatment in patients with prediabetes or type 2 diabetes mellitus and liver disease.
In a nutshell This study analyzed the effectiveness of pioglitazone (Actos) in patients with prediabetes or type 2 diabetes (T2D) and nonalcoholic fatty liver disease (NAFLD). The authors concluded that pioglitazone can significantly improve liver function in these patients. Some background NAFLD is the accumulation of fat cells in the...Read More
In a nutshell This review looked at whether exercise can improve heart rate variability (HRV) for patients with type 2 diabetes (T2D). It found that exercise improved HRV, which indicates better nerve health of the heart. Some background Over time, high blood glucose (sugar) from diabetes can cause nerve damage or neuropathy. People with diabetes...Read More
In a nutshell This study looked at how the Diabeloop system managed exercise for patients with type 1 diabetes (T1D). It found that people using this system did not have more hypoglycemia (dangerously low blood sugar) on days with exercise. Some background Physical exercise is a cornerstone of good health. Its many benefits include improved heart...Read More
In a nutshell In this study, the authors evaluated the effectiveness of adding dapagliflozin (Farxiga) to insulin therapy in patients with uncontrolled type 2 diabetes (T2D). The study showed that compared to increasing insulin doses, dapagliflozin improved glucose control while reducing weight and hypoglycemia (dangerously low blood...Read More