In a nutshell This study examined the effects of consuming soymilk and probiotics on risk factors related to heart and blood vessel diseases in patients with type 2 diabetes (T2D). The study showed that the consumption of soymilk with probiotics might improve cardiovascular (CV) risk factors in these patients. Some background T2D is a...
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How does physical activity affect the occurrence of major diabetes-related complications?
In a nutshell This study evaluated evidence on the association between physical activity and major diabetes-related complications in patients with diabetes. The authors concluded that physical activity was associated with a reduction in the occurrence of major diabetes-related complications, even if performed at levels lower than recommended. Some...
Read MoreCan autologous cell therapy improve severe diabetic foot disease?
In a nutshell This study looked at the use of autologous cell therapy (ACT) to treat no-option chronic limb-threatening ischemia (NO-CLTI) in patients with diabetic patients. The study showed that compared to standard treatment, ACT resulted in a significant improvement in ischemia and food healing in these patients. Some background Diabetes...
Read MoreIs intermittent fasting safe and effective for individuals with insulin-treated type 2 diabetes?
In a nutshell This study investigated the safety and effectiveness of intermittent fasting (IF) for 3 non-consecutive days a week, over a period of 12 weeks in people with insulin-treated type 2 diabetes (T2D). The authors concluded that this dietary approach was safe and effective for controlling blood glucose, reducing total daily insulin requirements,...
Read MoreHow safe and effective is orally delivered insulin for patients with early-stage type 2 diabetes?
In a nutshell This study compared the safety and effectiveness of different doses of an oral insulin capsule formulation (Capsulin™) to patients with early-stage type 2 diabetes (T2D). The data showed that twice-daily, orally administered Capsulin at a dose of 150 international units (IU) was safe and resulted in a significant lowering...
Read MoreCan vitamin B12 supplementation improve the symptoms of diabetic peripheral neuropathy in patients with diabetes?
In a nutshell This review assessed the effect of vitamin B12 supplementation on clinical outcomes when used alone or combined with other treatments for diabetic peripheral neuropathy (PN). The authors concluded that a greater reduction of PN symptoms occurred with the use of B12 supplementation alone or in combination with other treatments compared to...
Read MoreDoes metformin use in pregnancy lead to childhood weight gain?
In a nutshell This study looked at the use of metformin (Glucophage) for the management of type 2 diabetes (T2D) in pregnancy. The study showed that compared to infants exposed to placebo, those exposed to metformin during pregnancy did not show any signs of increased weight or body mass index (BMI; a measurement of weight in relation to...
Read MoreHow effective and safe are ultra-rapid insulin analogues in insulin pumps for patients with type 1 diabetes?
In a nutshell This review assessed the effectiveness and safety of ultra-rapid insulin analogs (URIAs) with continuous subcutaneous insulin systems (CSII) in adults with type 1 diabetes (T1D). The authors concluded that URIAs were compatible with CSII systems and had a better glucose-lowering effect after meals compared to rapid-acting insulin...
Read MoreHow can counselling affect pancreatic beta-cell function in patients with type 2 diabetes?
In a nutshell This study analyzed the long-term effect of behavioral counseling on increasing daily physical activity (PA) and reducing sedentary (SED) time on changes in beta-cell (β-cell) function and glucose control in patients with type 2 diabetes (T2D). The authors concluded that increasing moderate-to-vigorous-intensity physical activity...
Read MoreIs real time glucose monitoring better than intermittent scanning for patients with type 1 diabetes?
In a nutshell This study compared intermittent scanning continuous glucose monitoring (isCGM) with real-time continuous glucose monitoring (rtCGM) for the treatment of type 1 diabetes (T1D). It found that compared to isCGM, rt CGM resulted in increased time spent in range and improved blood glucose control in these patients. Some background...
Read MoreBenefits of combination treatment for diabetic peripheral neuropathic pain.
In a nutshell This study evaluated the effectiveness and safety of combinations of anti-depressive medication for the treatment of diabetic peripheral neuropathic pain (DPNP) in patients with diabetes. The study showed that combination treatment improved pain in these patients and was well tolerated. Some background DPNP occurs in patients...
Read MoreReviewing the significance of very low carbohydrate diets in type 2 diabetes.
In a nutshell This study compared the effect of very low carbohydrate (VLC) or ketogenic diets (KDs) with higher carbohydrate diets in patients with pre-diabetes or type 2 diabetes (T2D). The data showed that reduced levels of glycated hemoglobin (HbA1c) and triglycerides may occur with VLC or KDs, but with limited advantages over other diets. Some...
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