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Treatment Posts on Medivizor

Ending trastuzumab treatment in patients with HER2-positive metastatic breast cancer who are in radiological complete remission

Posted by on Oct 20, 2019 in Breast cancer | 0 comments

In a nutshell This study aimed to investigate the effect of stopping trastuzumab treatment in patients with HER2-positive metastatic breast cancer with radiological complete remission.   This study concluded that trastuzumab may be safely stopped in selected patients with radiological complete...

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Selegiline improves the treatment of patients with early Parkinson’s disease

Posted by on Oct 20, 2019 in Parkinson's Disease | 0 comments

In a nutshell This study investigated the long-term effectiveness and safety of selegiline (Zelapar) in Japanese patients with early Parkinson's disease. Researchers suggested that selegiline improved the outcomes of these patients with manageable side effects. Some background Parkinson's disease (PD) is a chronic disease that affects the...

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Evaluating the safety and effectiveness of pembrolizumab in elderly patients with advanced non-small cell lung cancer

Posted by on Oct 20, 2019 in Lung cancer | 0 comments

In a nutshell This study investigated the safety and effectiveness of pembrolizumab (Keytruda) in patients of 75 years or older with PD-L1 positive non-small-cell-lung cancer (NSCLC). Authors concluded that pembrolizumab improved overall survival and was safer than chemotherapy in these patients. Some background Lung cancer is one of the most common...

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An update on the long-term safety and effectiveness of etanercept in juvenile idiopathic arthritis

Posted by on Oct 20, 2019 in Rheumatoid Arthritis | 0 comments

In a nutshell This study investigated the long-term safety and effectiveness of etanercept (Enbrel) in juvenile idiopathic arthritis (JIA).  They found that etanercept is well tolerated and effective on the long-term in patients with JIA.  Some background Juvenile idiopathic arthritis (JIA) is an inflammatory condition...

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A review of 5-year outcomes after PCI or CABG intervention for left main coronary disease

Posted by on Oct 20, 2019 in Coronary artery disease | 0 comments

In a nutshell This study investigated outcomes after 2 surgical interventions to treat coronary artery disease (CAD) in the left main artery. They found no difference in outcomes after percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) in these patients.  Some background Coronary artery disease (CAD) is caused by...

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Golimumab in rheumatoid arthritis – investigating the safety and efficacy of intravenous administration

Posted by on Oct 20, 2019 in Rheumatoid Arthritis | 0 comments

In a nutshell This study investigated golimumab (Simponi; GLM) in patients with rheumatoid arthritis (RA) in patients over 65 compared to those under 65.  They found that intravenous (IV) GLM was effective and well tolerated in these patients. Some background Rheumatoid arthritis (RA) is caused by chronic inflammation in the joints. RA...

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Should additional chemotherapy be added to chemoradiotherapy in patients with inoperable non-small cell lung cancer?

Posted by on Oct 20, 2019 in Lung cancer | 0 comments

In a nutshell This study examined how effective additional chemotherapy alongside chemo-radiotherapy is in patients with locally advanced non-small cell lung cancer. The study found that additional chemotherapy did not bring survival benefits in these patients. Some background Non-small cell lung cancer (NSCLC) can be difficult to treat. There are a...

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Evaluating long-term outcomes of nivolumab plus ipilimumab for patients with advanced melanoma

Posted by on Oct 20, 2019 in Melanoma | 0 comments

In a nutshell This study compared nivolumab (Opdivo) plus ipilimumab (Yervoy) to either drug alone for the treatment of advanced melanoma. The authors concluded that nivolumab plus ipilimumab or nivolumab alone increased survival compared to ipilimumab alone for these patients. Some background Advanced melanoma is a type of skin cancer that...

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Surgery followed by chemotherapy improves the outcomes of patients with rectal cancer

Posted by on Oct 13, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness of surgery followed by chemotherapy without chemoradiotherapy (CRT) before surgery to treat rectal cancer. Researchers suggested that this treatment improves the outcomes of these patients.  Some background Colorectal cancer is the third most common cancer worldwide. The standard...

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Can ipragliflozin treatment help lower insulin dose in patients with T2D receiving insulin therapy?

Posted by on Oct 13, 2019 in Diabetes mellitus | 0 comments

In a nutshell This study evaluated the safety and effectiveness of ipragliflozin (Suglat) in patients with type 2 diabetes (T2D). This study concluded that ipragliflozin helped reduce insulin dose by 30%, with minimal side effects. Some background Treatment for T2D aims to achieve good blood glucose control while avoiding hypoglycemia (dangerously low...

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Evaluating outcomes in patients with multiple myeloma after RVD therapy followed by stem cell transplant outside of clinical trials

Posted by on Oct 13, 2019 in Multiple Myeloma | 0 comments

In a nutshell This study assessed the safety and effectiveness of RVD (lenalidomide, bortezomib, dexamethasone) in patients with multiple myeloma before a stem cell transplant (SCT) in a real-life setting (outside of clinical trials). This study concluded that this treatment was safe and effective for these patients. Some background Multiple myeloma...

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