In a nutshell This article investigated the long-term safety and effectiveness of oncoplastic breast surgery (removal of the tumor and breast reconstruction at the same time) on women survivors of breast cancer. The authors concluded that this treatment is safe and resulted in acceptable long-term outcomes. Some background Breast conservative...
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Adding everolimus to endocrine therapy in patients with HER2- ER+ advanced breast cancer
In a nutshell This study wanted to find out if treating breast cancer with everolimus (Afintor) and endocrine therapy is better than only treating with endocrine therapy. The study found that using everolimus in addition to endocrine therapy had a significant benefit to survival in these patients. Some background Breast cancer is classified into types...
Read MoreLength of treatment with trastuzumab in HER2+ early stage breast cancer
In a nutshell This study wanted to find out what the best length of treatment with trastuzumab (Herceptin) is for HER2+ early stage breast cancer. The study found that at least one year of treatment had the best results in terms of how well it worked, and the cost-effectiveness. Some background HER-2 positive breast cancer is a type of cancer where...
Read MoreTreating BRCA1/2 mutated breast cancer that has spread with lurbinectedin
In a nutshell This study wanted to find out how well lurbinectedin (PM01183) works in treatment of breast cancer with BRCA1/2 mutations (abnormal genes), which has spread. The study found that lurbinectedin worked well in treating patients with BRCA1/2 mutated breast cancer which had spread. Some background BRCA1 and BRCA2 are genes that stop tumors...
Read MoreTreating BRCA1/2 mutated breast cancer that has spread with lurbinectedin
In a nutshell This study wanted to find out how well lurbinectedin (PM01183) works in treatment of breast cancer with BRCA1/2 mutations (abnormal genes), which has spread. The study found that lurbinectedin worked well in treating patients with BRCA1/2 mutated breast cancer which had spread. Some background BRCA1 and BRCA2 are genes that stop tumors...
Read MoreTreatment time with trastuzumab in HER-2 positive breast cancer
In a nutshell This study wanted to find out if shortening treatment for HER2-positive breast cancer with trastuzumab (Herceptin) from 1 year to 9 weeks would make the treatment less effective. The study found that treatment for nine weeks was not less effective than treatment for 1 year. Some background HER-2 positive breast cancer is a type of...
Read MoreHow effective is myofascial release after breast cancer surgery?
In a nutshell This article investigated the safety and effectiveness of myofascial release (MR) therapy on women survivors of breast cancer. The authors concluded that MR therapy is safe and resulted in physical benefits (overall shoulder movement, functionality, pain). Some background Surgery and radiation are among the main treatments for...
Read MoreIntraoperative electron radiotherapy in treating breast cancer
In a nutshell This study wanted to find out what benefits there were to doing electron radiation therapy during surgery alongside normal radiation therapy for women with breast cancer. The study found that ten years after surgery, almost all the patients who had electron radiotherapy during surgery had no reoccurrence of breast cancer. Some...
Read MoreAdding ixabepilone to capecitabine treatment for triple negative breast cancer.
In a nutshell This study wanted to find out if ixabepilone (Ixempra) and capecitabine (Xeloda) work for treating triple-negative breast cancer in patients with hard to treat disease compared to using capecitabine alone. The study found that adding ixabepilone to treatment resulted in longer survival without the cancer progressing. Some background...
Read MoreJoint pain management in obese breast cancer patients treated with aromatase inhibitors
In a nutshell This article investigated the safety and effectiveness of adding Omega-3 fatty acid (O3-FA) to the management of joint pain in patients with breast cancer treated with aromatase inhibitors. The authors concluded that the addition of O3-FA is safe and gave the greatest benefit to patients who were obese. Some background...
Read MoreAdding pertuzumab to treatment in breast cancer
In a nutshell This study wanted to find out which treatment is better for breast cancer, chemotherapy plus trastuzumab (Herceptin) and surgery, or pertuzumab (Perjeta), and chemotherapy plus trastuzumab (Herceptin) and surgery. The study found that adding pertuzumab to the standard treatment worked better to completely remove all signs of cancer compared...
Read MoreTherapy for women with breast cancer experiencing depression
In a nutshell This paper was looking at which type of therapy is best for women with breast cancer who are experiencing major depression. The study found that all three therapies tested resulted in equal benefit for the patients. Some background It is well known that there is an association between being diagnosed with breast cancer and...
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