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Breast cancer Posts on Medivizor

Trastuzumab emtansine with or without pertuzumab versus trastuzumab with taxane for HER2+ advanced breast cancer

Posted by on Nov 2, 2019 in Breast cancer | 0 comments

In a nutshell This study wanted to find out which treatment resulted in better overall survival for patients with HER2+ breast cancer; trastuzumab emtansine (Kadcycla) with or without pertuzumab (Perjeta), or trastuzumab (Herceptin) plus a taxane. The study found that the overall survival was similar across...

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Looking for patients with advanced triple negative breast cancer to test an experimental drug with three functions

Posted by on Oct 31, 2019 in Breast cancer | 0 comments

In a nutshell This trial is examining the safety and effectiveness of experimental drug mRNA-2752 in patients with advanced triple-negative breast cancer. The main outcome of the trial will be the number of side effects experienced by patients and response to treatment. This trial is recruiting in the United States and Israel. The details...

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Searching for patients with early breast cancer to trial a partial-radiation treatment

Posted by on Oct 24, 2019 in Breast cancer | 0 comments

In a nutshell This trial aims to find out what dose of radiation therapy is effective in the shortest time period for women with newly diagnosed breast cancer, or ductal carcinoma in-situ (DCIS). The main outcome that will be measured is if patients experience any side effects. The study is taking place in New Jersey and New York, the United States. The...

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Looking for postmenopausal women with advanced breast cancer to try a hormonal therapy

Posted by on Oct 24, 2019 in Breast cancer | 0 comments

In a nutshell This study is looking for postmenopausal patients with advanced breast cancer with an ESR1 mutation to compare lasofoxifene (Fablyn) to fulvestrant (Faslodex). The main outcome measured in this trial will be the patient’s survival without tumor growth or spread. This trial is recruiting in multiple locations in the United...

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Comparing endocrine treatment versus chemotherapy for metastatic breast cancer

Posted by on Oct 22, 2019 in Breast cancer | 0 comments

In a nutshell This study compared hormone therapy and chemotherapy for the treatment of metastatic (cancer that has spread) breast cancer. The authors concluded that hormone therapy plus targeted therapy is better than chemotherapy for patients with metastatic breast cancer. Some background Different types of breast cancer have different receptors....

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Ending trastuzumab treatment in patients with HER2-positive metastatic breast cancer who are in radiological complete remission

Posted by on Oct 20, 2019 in Breast cancer | 0 comments

In a nutshell This study aimed to investigate the effect of stopping trastuzumab treatment in patients with HER2-positive metastatic breast cancer with radiological complete remission.   This study concluded that trastuzumab may be safely stopped in selected patients with radiological complete...

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Looking for patients with hormone-receptor positive metastatic breast cancer to test an experimental biological drug

Posted by on Sep 30, 2019 in Breast cancer | 0 comments

In a nutshell This study is examining the effectiveness of biological drug sacituzumab govitecan (IMMU-132) compared to standard treatments for patients with hormone receptor-positive metastatic breast cancer. The main outcomes that will be measured are cancer responsiveness to the drug and survival of patients without the cancer growing. This trial...

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Evaluating the long-term outcomes of breast-conserving therapy for women with ductal carcinoma in situ.

Posted by on Sep 30, 2019 in Breast cancer | 0 comments

In a nutshell This study wanted to find out what the long-term outcomes were for women with ductal carcinoma in situ (DCIS) who had breast-conserving therapy. The study found that after 10 years, the risk of recurrence of cancer in the same breast was very low.  Some background There are a number of treatment options for DCIS. Some women opt...

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