In a nutshell This study investigated the effectiveness of Pilates compared with circuit-based exercise in reducing joint pain during hormone therapy for women with breast cancer. The data showed that Pilates was more effective than circuit-based exercise in reducing joint pain for these patients. Some background Many of the patients with...
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In a nutshell This study is searching for participants with advanced solid tumors including breast cancer to examine the safety and effectiveness of experimental drug avapritinib (AYVAKIT). The main outcomes to be measured are the response to treatment and side effects. This trial is being conducted in Texas, US. The details Some cancers grow as a...
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In a nutshell This study compared the effectiveness and safety outcomes of radiotherapy (RT) after immediate autologous breast reconstruction (IABR) following breast-conserving surgery (BCS) in patients with breast cancer. The data showed that RT following IABR provided aesthetically satisfactory results with manageable side effects in these...
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In a nutshell This study compared the effectiveness and safety outcomes of current chemotherapy regimens for treatment in patients with early-stage breast cancer (BC). The data showed that the current treatment regimens have similar effectiveness. Some background BC is classified into different subtypes depending on the presence or...
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In a nutshell This study aimed to compare the effectiveness and safety of endocrine therapy (ET) or chemotherapy (CT) before surgery in patients with invasive ductal carcinoma (IDC) of the breast that is hormone receptor (HR) positive (+) and human epidermal growth factor receptor 2 (ERBB2) negative (-). The study concluded CT before...
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In a nutshell This study compared the safety and effectiveness of pyrotinib (SHR-1258) plus capecitabine (Xeloda) versus lapatinib (Tyverb) plus capecitabine in patients with metastatic human epidermal growth factor (HER2)-positive breast cancer (BC) after previous treatment with trastuzumab (Herceptin) and chemotherapy. The data...
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In a nutshell This study investigated the effectiveness of fulvestrant (Faslodex) as a first-line treatment for postmenopausal women with estrogen receptor-positive (ER+) metastatic breast cancer (BC) in a real-world setting. The data showed that the outcomes of these patients in the real-world setting were similar to clinical trials...
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In a nutshell This study explored whether trastuzumab (Herceptin) is an efficient drug for the treatment of HER2-positive breast cancer (BC) in patients who have previously received radiotherapy (RT) after breast removal surgery. The authors found that trastuzumab reduced the recurrence of BC and improved survival without cancer coming...
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In a nutshell This study reported the final effectiveness and safety outcomes of neratinib treatment in patients with early-stage HER2+/HR+ breast cancer. The data showed that neratinib significantly improved invasive disease-free survival in these patients who initiated treatment within 1 year of trastuzumab-based therapy. Some background...
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In a nutshell This study compared the long-term effectiveness of integrated intensity-modulated radiation therapy (IMRT) and segmented 3D-conventional radiotherapy (3D-CRT) following breast-removal surgery (radical mastectomy) in patients with breast cancer (BC). The data showed that integrated IMRT reduced the recurrence rate in the long-term with...
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In a nutshell This article looked at the safety and effectiveness of abemaciclib (Verzenios) plus hormonal therapy (HT) in older patients with hormone receptor-positive (HR+)/HER-2 negative (HER2-) advanced breast cancer (BC). The authors concluded that abemaciclib + HT was effective across all age groups and while higher rates of side effects...
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In a nutshell This study evaluated the impact of different times after chemotherapy until breast cancer surgery on complications after surgery and survival outcomes. The data showed the optimal time to surgery (TTS) was between 21 and 28 days after chemotherapy in these patients. Some background Breast cancer (BC) is one of...
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