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Breast cancer Posts on Medivizor

The impact of beta-blockers, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on BC survival

Posted by on Apr 13, 2017 in Breast cancer | 0 comments

In a nutshell This study investigated whether beta blockers (BB), angiotensin-converting enzyme inhibitors (ACEi), and angiotensin receptor blockers (ARB) have a beneficial effect on breast cancer-specific survival (BCSS; the time between diagnosis and death from BC). The use of BB was found to be associated with better BCSS survival. Some...

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A comparison of how FEC120 treatment vs EC-docetaxel treatment affect survival in patients with node-positive primary breast cancer

Posted by on Apr 13, 2017 in Breast cancer | 0 comments

In a nutshell This study compared the side effects and outcome of two drug regimens in women with high-risk node-positive breast cancer (BC). Both treatment regimens were found to have similar survival outcomes. Some background Standard treatment in node positive BC (cancer that has spread to the lymph nodes) consists of two categories of...

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The role of dexamethasone mouthwash in preventing everolimus-related stomatitis in women with breast cancer

Posted by on Apr 13, 2017 in Breast cancer | 0 comments

In a nutshell This study investigated the use of dexamethasone (Ozurdex) mouthwash for preventing stomatitis in patients with breast cancer(BC).  The use of dexamethasone oral solution was found to significantly reduce the incidence and severity of stomatitis. Some background Everolimus (Afinitor) and exemestane (Aromasin) are mTOR inhibitors...

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The pre-operative use of accelerated partial breast irradiation in treating early-stage breast cancer

Posted by on Apr 13, 2017 in Breast cancer | 0 comments

In a nutshell This study investigated whether accelerated partial-breast irradiation (APBI) was useful for preoperative treatment of early-stage breast cancer (BC) patients. APBI was found to be an effective treatment option with good cosmetic results for certain early-stage BC patients. Some background Breast conserving therapy (surgery to remove...

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How radiotherapy for breast cancer influences long-term the risk of lung cancer and heart disease

Posted by on Apr 13, 2017 in Breast cancer | 0 comments

In a nutshell This study investigated the results of previous trials to determine the effects of breast cancer (BC) radiotherapy (RT) on the long-term risk of developing other health conditions later in life. This study determined that for long-term smokers, the future health risks associated with RT may outweigh the benefits. Some background RT...

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The effectiveness and cardiac safety of CMF plus trastuzumab in HER2-positive metastatic breast cancer

Posted by on Apr 13, 2017 in Breast cancer | 0 comments

In a nutshell This study investigated the safety and effectiveness of treatment with combination cyclophosphamide (Cytoxan), methotrexate (Otrexup) and 5-fluoruoracil (Efudex) (CMF) plus trastuzumab (Herceptin) in HER2-positive metastatic breast cancer (MBC, cancer that has spread beyond the breast) patients. CMF plus trastuzumab (CMF+T) was found to...

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How effective is metronomic chemotherapy with vinorelbine and capecitabine in patients with advanced HER2-negative breast cancer?

Posted by on Apr 3, 2017 in Breast cancer | 0 comments

In a nutshell This study investigated whether metronomic chemotherapy with oral vinorelbine (Navelbine) and capecitabine (Xeloda) was effective in treating patients with advanced HER2-negative breast cancer (BC). This form of treatment was found to be safe and effective for this patients group. Some background Metronomic chemotherapy is a form of...

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Comparing the effects of combined PI3K inhibitor/endocrine therapy versus endocrine therapy alone in ER-positive breast cancer

Posted by on Apr 3, 2017 in Breast cancer | 0 comments

In a nutshell This study investigated whether the addition of the PI3K inhibitor pictilisib (Stemolecule GDC-0941) can increase the anti-tumor effects of anastrozole (Arimidex) in patients with estrogen receptor-positive (ER-positive) primary breast cancer (BC). Combined treatment with pictilisib (PIC)...

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The beneficial effects of trastuzumab on locoregional control in HER2-positive breast cancer patients.

Posted by on Mar 27, 2017 in Breast cancer | 0 comments

In a nutshell This study investigated the effects of trastuzumab (Herceptin) on the locoregional control (management in the area in which it arose) of patients with HER2-positive breast cancer (HER2+BC) following radiotherapy (RT). Trastuzumab administered alongside RT was found to be associated with a significantly reduced rate of locoregional...

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The impact of exercise on the risk of cardiovascular events in women with non-metastatic breast cancer

Posted by on Mar 20, 2017 in Breast cancer | 0 comments

In a nutshell This study investigated whether exercise was associated with a reduction in the risk of cardiovascular disease (CVD) in patients with non-metastatic breast cancer (BC). Exercise was found to be linked to a significant reduction in the risk of CVD for this patient group. Some background CVD is a leading cause of death among women with...

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How does hormone receptor status affect patient response to trastuzumab therapy in metastatic breast cancer

Posted by on Mar 20, 2017 in Breast cancer | 0 comments

In a nutshell This study investigated the clinical factors that influence patient response to trastuzumab (Herceptin) therapy in human epidermal growth factor receptor 2 positive (HER2+) metastatic breast cancer (MBC). Hormone receptor (HR) status was found to be a possible predictor of a strong response to trastuzumab-based therapy. Some background...

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