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Breast cancer Posts on Medivizor

Searching for patients with advanced triple-negative breast cancer to trial a treatment combination

Searching for patients with advanced triple-negative breast cancer to trial a treatment combination

Posted by on Sep 6, 2020 in Breast cancer | 0 comments

In a nutshell This trial is aiming to examine the effectiveness of ipatasertib in combination with atezolizumab (Tecentriq) and paclitaxel (Taxol) for the treatment of advanced triple-negative breast cancer (TNBC) that cannot be surgically removed. The main outcomes to be measured in this trial is survival without progression of the disease and...

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Does neratinib plus capecitabine benefit patients with heavily treated HER2-positive metastatic breast cancer?

Does neratinib plus capecitabine benefit patients with heavily treated HER2-positive metastatic breast cancer?

Posted by on Aug 20, 2020 in Breast cancer | 0 comments

In a nutshell This trial compared the effectiveness of neratinib (Nerlynx) plus capecitabine (Xeloda) in treating metastatic breast cancer compared to lapatinib (Tykerb) plus capecitabine in patients who have received 2 or more treatment lines. The authors found that neratinib plus capecitabine (N+C) resulted...

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Improving the tolerability of neratinib in patients with early-stage HER2-positive breast cancer.

Improving the tolerability of neratinib in patients with early-stage HER2-positive breast cancer.

Posted by on Aug 15, 2020 in Breast cancer | 0 comments

In a nutshell This trial evaluated strategies to improve diarrhea as a side effect of neratinib (Nerlynx) treatment in patients with HER2-positive breast cancer (BC). The authors showed that slowly increasing the doses of neratinib or taking anti-diarrhea medication can improve this side effect. Some background Neratinib (Nerlynx) is a targeted...

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Searching for patients with advanced breast cancer to trial an experimental drug combination

Searching for patients with advanced breast cancer to trial an experimental drug combination

Posted by on Aug 15, 2020 in Breast cancer | 0 comments

In a nutshell This phase 2 trial will investigate the safety of experimental treatment zanidatamab (ZW25) in combination with palbociclib (Ibrance) and fulvestrant (Faslodex) in patients with advanced breast cancer (BC). The main outcomes evaluated will be the rate of side effects and survival without cancer worsening. This trial is...

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Differential effects of docetaxel-based chemotherapy according to body mass in patients with early breast cancer

Differential effects of docetaxel-based chemotherapy according to body mass in patients with early breast cancer

Posted by on Aug 9, 2020 in Breast cancer | 0 comments

In a nutshell The study investigated whether chemotherapy after surgery with or without docetaxel (Taxotere) has different outcomes in patients with different body mass indexes (BMI; a measurement of body weight in relation to height) and early breast cancer (BC). The main finding was that patients responded differently to docetaxel based on...

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COVID-19 with Cancer

COVID-19 with Cancer

Posted by on Jul 31, 2020 in Blog, Breast cancer, Colorectal cancer, Coronavirus / COVID-19, Hodgkin's lymphoma, Leukemia, Lung cancer, Lymphoma, Melanoma, Multiple Myeloma, Non-Hodgkin lymphoma, Prostate cancer | 3 comments

Recent research presented at a virtual meeting of the American Association for Cancer Research 1 indicates the need for greater care and continued social distancing for those who are in treatment for cancer and – in one study that was presented – those who have a recent history of cancer (the research looked at people from 2015 to the...

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Are weight changes after breast cancer diagnosis associated with poorer survival?

Are weight changes after breast cancer diagnosis associated with poorer survival?

Posted by on Jul 26, 2020 in Breast cancer | 0 comments

In a nutshell The aim of this study was to assess whether weight changes after diagnosis of breast cancer (BC) were associated with survival. The study found that a weight changes of over 10% were associated with a poorer outcome when compared to weight maintenance (within 5%).  Some background BC remains one of the most commonly diagnosed...

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The outcomes of trastuzumab emtansine in patients with brain metastasis from HER2-positive breast cancer

The outcomes of trastuzumab emtansine in patients with brain metastasis from HER2-positive breast cancer

Posted by on Jul 19, 2020 in Breast cancer | 0 comments

In a nutshell The study evaluated the effects of trastuzumab emtansine (T-DM1; Kadcyla) to treat patients with brain metastasis (BM) from HER2-positive metastatic breast cancer (mBC). The main finding was that T-DM1 was safe and effective in such patients. Some background HER-2 positive mBC cells have an excess of the HER-2 protein. Such cancers...

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Long term effects of hypofractionated prone intensity-modulated radiation therapy after breast conservation surgery in patients with breast cancer

Long term effects of hypofractionated prone intensity-modulated radiation therapy after breast conservation surgery in patients with breast cancer

Posted by on Jul 12, 2020 in Breast cancer | 0 comments

In a nutshell The study evaluated long-term outcomes of combining hypofractionated intensity-modulated radiation therapy (H-IMRT) with prone-positioning in patients after conservation surgery for breast cancer. The authors found that this combination safely controlled cancer locally without affecting regional lymph nodes. Some background Adjuvant...

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The effects of cholesterol-lowering drugs on breast cancer relapse in postmenopausal women under aromatase inhibitor treatment

The effects of cholesterol-lowering drugs on breast cancer relapse in postmenopausal women under aromatase inhibitor treatment

Posted by on Jul 5, 2020 in Breast cancer | 0 comments

In a nutshell The study evaluated the link between statin (cholesterol-lowering drugs) use and risks of breast cancer (BC) relapse under adjuvant aromatase inhibitors (AI) therapy in women after their menopause. The main finding was that statin use was related with lower risks of BC relapse in such patients. Some background Women with...

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Evaluating the effects of chemotherapy on cognitive function in patients with early breast cancer

Evaluating the effects of chemotherapy on cognitive function in patients with early breast cancer

Posted by on Jun 28, 2020 in Breast cancer | 0 comments

In a nutshell The study evaluated the contribution of chemotherapy on cancer-related cognitive impairment (CRCI) reported by women with early breast cancer. The authors found that chemotherapy added to hormonal therapy caused early and short-term CRCI in such patients, compared to hormonal therapy alone. Some background CRCI refers to problems in...

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Does pembrolizumab added to chemotherapy before surgery improve the outcomes of patients with early triple negative breast cancer?

Does pembrolizumab added to chemotherapy before surgery improve the outcomes of patients with early triple negative breast cancer?

Posted by on Jun 28, 2020 in Breast cancer | 0 comments

In a nutshell The study assessed whether pembrolizumab (Keytruda) could be used in addition to neoadjuvant chemotherapy (NAC; chemotherapy before surgery) to improve the outcomes of patients with early triple-negative breast cancer (TNBC). The study found that more patients treated with pembrolizumab had a complete response. Some...

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