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Hodgkin’s lymphoma Posts on Medivizor

Optimal treatment for relapsed and unresponsive nodular lymphocyte-predominant Hodgkin lymphoma

Posted by on Apr 18, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study aimed to investigate treatments and outcomes for patients with relapsed or unresponsive nodular lymphocyte-predominant Hodgkin lymphoma. This study concluded that these patients have a good overall prognosis and treatments should be chosen individually. Some background Radiotherapy (RT), chemotherapy (CT) and rituximab...

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Evaluating long-term outcomes after radiation and stem cell transplantation for recurrent or unresponsive Hodgkin lymphoma

Posted by on Apr 15, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study evaluated the long-term outcomes of patients with recurrent or non-responsive classical Hodgkin’s lymphoma (cHL) after undergoing radiation, chemotherapy, and autologous stem cell transplantation (autoSCT). This study concluded that total lymphoid irradiation (TLI) therapy before a bone marrow transplant can improve...

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The use of brentuximab vedotin before transplant for patients with Hodgkin’s lymphoma

Posted by on Mar 29, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study aimed to compare outcomes for patients with Hodgkin’s lymphoma who received brentuximab vedotin (Adcetris) compared to chemotherapy before a stem cell transplant. This study concluded that patients who received brentuximab vedotin had a better survival. Some background Allogeneic hematopoietic stem cell...

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Comparing conditioning regimens before stem cell transplantation for patients with Hodgkin lymphoma

Posted by on Mar 28, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study evaluated the safety and effectiveness of two chemotherapy regimens before autologous stem cell transplantation (ASCT) for patients with Hodgkin lymphoma (HL). This study concluded that BEAM conditioning before ASCT significantly improved the outcomes of these patients. Some background About 20 – 30% of patients...

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Evaluating PD-1 inhibitors for patients with Hodgkin lymphoma in a real-world setting

Posted by on Mar 26, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study evaluated the safety and effectiveness of PD-1 inhibitors for patients with classical Hodgkin lymphoma (cHL) outside of clinical trials. This study concluded that PD-1 inhibitors are safe and effective for these patients. Some background Standard first-line chemotherapy is highly effective in treating 70 – 80% of...

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Evaluating the effects of music during chemotherapy for patients with lymphoma

Posted by on Mar 26, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study examined whether listening to music during chemotherapy reduces anxiety in patients with newly diagnosed lymphoma. This study concluded that live music reduced anxiety in these patients. Some background During and after chemotherapy treatment, patients with lymphoma may experience severe anxiety. Fearful thoughts about the...

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Does donor type and melphalan dose impact outcomes for patients with lymphoma who receive a stem cell transplant?

Posted by on Mar 26, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study aimed to investigate the impact of donor type and melphalan (Alkeran) dose on transplant outcomes for patients with lymphoma. This study concluded that different donor types and melphalan doses have similar outcomes for these patients. Some background Allogenic hematopoietic stem cell transplant (allo-HSCT) is a...

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The impact of graft-versus-lymphoma effect on outcomes after reduced intensity conditioned stem cell transplant

Posted by on Mar 26, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study aimed to investigate the impact of the graft-versus-lymphoma effect on the outcomes for patients with lymphoma who are treated with reduced-intensity conditioning (RIC) with alemtuzumab (Lemtrada) allogeneic hematopoietic stem cell transplant (allo-HSCT). This study concluded that the graft-versus-lymphoma effect leads...

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Is nivolumab an effective treatment for relapsed and unresponsive Hodgkin lymphoma?

Posted by on Mar 16, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study examined if nivolumab is an effective treatment for relapsed and unresponsive Hodgkin lymphoma. This study concluded that nivolumab is an effective treatment for these patients, regardless of previous stem cell treatment status. Some background Standard treatment for patients with Hodgkin lymphoma (HL) which has relapsed or...

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Evaluating the impact of interim imaging on treatment outcomes for advanced cHL

Posted by on Mar 10, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study investigated the impact of interim functional imaging (IFI) on the outcomes of treatment for advanced classical Hodgkin lymphoma (cHL). This study found that patients with positive scan results were more likely to disease progression. Some background ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine) is the...

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