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Evaluating side effects of artificial gonadotropins

Evaluating side effects of artificial gonadotropins

Posted by on Nov 29, 2020 in Infertility | 0 comments

In a nutshell This review looked at how often artificial gonadotropin hormones such as human follitropin alpha (Gonal-F) caused ovarian hyperstimulation syndrome (OHSS) or blood clots. It found that these conditions are infrequent side effects of using gonadotropins to stimulate the ovaries. Some background In a natural menstrual cycle,...

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Follitropin delta in controlled ovarian stimulation – what dose produces similar effects to follitropin alpha?

Follitropin delta in controlled ovarian stimulation – what dose produces similar effects to follitropin alpha?

Posted by on Nov 6, 2020 in Infertility | 0 comments

In a nutshell This study investigated the best dose of follitropin delta (FD; Rekovelle) in women undergoing controlled ovarian stimulation (COS).  They found that 10 micrograms of FD has similar effectiveness to the standard dose of follitropin alpha (FA; Gonal-F). Some background Assisted reproductive technology (ART)...

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Does preimplantation genetic testing for aneuploidy improve fertility outcomes for couples with severe male infertility?

Does preimplantation genetic testing for aneuploidy improve fertility outcomes for couples with severe male infertility?

Posted by on Nov 6, 2020 in Infertility | 0 comments

In a nutshell This study investigated preimplantation genetic testing for aneuploidy (PGT-A) in couples with severe male infertility. They found that PGT-A did not improve fertility outcomes in these couples.  Some background Infertility affects men and women. Male factor infertility (MFI) is the cause of infertility in 30-50% of...

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Predicting IVF fertilization rates

Predicting IVF fertilization rates

Posted by on Nov 1, 2020 in Infertility | 0 comments

In a nutshell This study created a model to predict how well eggs (oocytes) develop embryos during in vitro fertilization (IVF). It found that patients with lower doses of gonadotropin (GN) hormones had better fertilization rates (FR). It also found that patients with diminished ovarian reserve (DOR) could have a high FR. Some background The...

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Does enriched growth medium improve IVF outcomes?

Does enriched growth medium improve IVF outcomes?

Posted by on Oct 18, 2020 in Infertility | 0 comments

In a nutshell This review looked at adding hyaluronic acid (HA) to the medium used to grow embryos during in vitro fertilization (IVF). It found that using HA may increase IVF birth rates. Some background The infertility treatment IVF involves fertilizing an egg and allowing it to grow it for several days in the laboratory. The embryos are...

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Does sperm freezing affect fertility outcomes in men with obstructive azoospermia?

Does sperm freezing affect fertility outcomes in men with obstructive azoospermia?

Posted by on Oct 17, 2020 in Infertility | 0 comments

In a nutshell This study investigated if sperm cryopreservation (freezing) affects fertility outcomes for men with obstructive azoospermia (OA; lack of sperm cells in the semen due to a blockage).  The authors found that the clinical pregnancy rate (CPR) was lower with the use of frozen vs fresh epididymal sperm.  Some background There...

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Is natural cycle or hormone replacement cycle associated with better pregnancy rates in women undergoing frozen embryo transfer?

Is natural cycle or hormone replacement cycle associated with better pregnancy rates in women undergoing frozen embryo transfer?

Posted by on Oct 17, 2020 in Infertility | 0 comments

In a nutshell This study compared natural cycle (NC) or hormone replacement cycle (HRC) in terms of fertility outcomes in women undergoing frozen embryo transfer (fzET).  They found that fertility outcomes were similar with NC or HRC.  Some background Assisted reproductive technology (ART) is used to treat infertility. ART includes...

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Comparing IVF protocols and genetic testing outcomes

Comparing IVF protocols and genetic testing outcomes

Posted by on Oct 11, 2020 in Infertility | 0 comments

In a nutshell This study looked at two protocols for in vitro fertilization (IVF) using different timing of medications to suppress the body’s own hormones. It found that patients using a long-acting protocol had fewer embryos with unusual chromosomes (genetic material). Some background Women are born with most of their oocytes (eggs) already...

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Is testosterone replacement therapy more common in men undergoing assisted reproduction?

Is testosterone replacement therapy more common in men undergoing assisted reproduction?

Posted by on Oct 10, 2020 in Infertility | 0 comments

In a nutshell This study investigated the rate of testosterone replacement therapy (TRT) in men undergoing assisted reproduction (AR). They found that men undergoing AR were more likely to need TRT. Some background Low testosterone (T) is becoming increasingly common worldwide. Low T in men is associated with a number of conditions. This...

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Does previous TORCH infections affect fertility and neonatal outcomes after assisted reproduction?

Does previous TORCH infections affect fertility and neonatal outcomes after assisted reproduction?

Posted by on Oct 4, 2020 in Infertility | 0 comments

In a nutshell This study investigated if previous TORCH infections affect outcomes during assisted reproduction (AR) such as in vitro fertilization (IVF) or intracytoplasmatic sperm injection (ICSI). They found that there was no link between previous TORCH infections and negative fertility/neonatal outcomes. Some background A healthy...

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