In a nutshell This study looked at cholesterol and other lipid (fats) levels in the blood in women undergoing in vitro fertilization (IVF). It found that women with more heart-healthy lipid levels had better IVF outcomes. Some background Lipid levels are an important measure of health. While a lipid can be any oily or waxy substance in the body,...
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In a nutshell This study compared letrozole (Femara), clomiphene (Clomid), or no ovarian stimulation for women with polycystic ovarian syndrome (PCOS). It found that letrozole led to the uterus being more receptive to an embryo, and to higher pregnancy rates. Some background Women with PCOS do not ovulate frequently or at all. Patients who want...
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In a nutshell This review looked at whether phosphodiesterase 5 (PDE5) inhibitors such as sildenafil (Viagra) can improve male fertility. It found that these medications improve sperm concentration, shape, and movement. Some background PDE5 inhibitors are the most common treatment for erectile dysfunction (ED). These medications increase the...
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In a nutshell This review looked at the effect of endometriosis surgery before in vitro fertilization (IVF). It found that surgery led to better pregnancy outcomes for patients with severe endometriosis. Some background Endometriosis is a condition in which cells from the lining of the uterus grow on the ovaries, Fallopian tubes, or other places...
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In a nutshell This study looked at how a diet change and exercise program impacted the fertility of men living in polluted areas. It found that a healthy diet and exercise improved sperm quality in these men. Some background Fertility is an indicator of overall health. A healthful diet and regular physical exercise can support both fertility and...
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In a nutshell This study looked at etanercept (Enbrel) for women who have had repeated unsuccessful in vitro fertilization (IVF). It found that etanercept led to good pregnancy rates in these patients. Some background The uterus forms a connection between the vagina, which is open to the outside, and the inside of the body. If harmful bacteria...
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In a nutshell This study compared two types of frozen embryo transfer (FET) for women with polycystic ovarian syndrome (PCOS). It found that stimulating ovulation with letrozole (Femara) led to fewer pregnancy complications than using an artificial cycle. Some background FET is an infertility treatment in which a frozen embryo is transferred into...
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In a nutshell This review looked at antioxidants for men with infertility. They found that antioxidants can improve semen quality, including for men with varicoceles (VCs). Some background Male infertility, such as low sperm count, contributes to half of all cases of infertility. Sperm require specific conditions to develop normally. Sperm are...
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In a nutshell This analysis looked at which factors influence the risk of miscarriage for women with polycystic ovarian syndrome (PCOS) who were undergoing infertility treatment. It found that being overweight and insulin resistance can increase miscarriage risk in these patients. Some background Metabolism, hormones, and fertility are closely...
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In a nutshell This review looked at treatments for women who have had multiple cycles of in vitro fertilization (IVF) without a pregnancy. It found that there are multiple options that may improve implantation rates, including white blood cell infusions or factors which grow the lining of the uterus. Some background IVF is a widely used...
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In a nutshell This review looked at the safety of using letrozole (Femara) to promote ovulation. It found that letrozole does not increase birth defects or miscarriage. It also found that letrozole led to higher birth rates than clomiphene citrate (Clomid). Some background Infertility is a growing issue. Not ovulating regularly, or releasing an egg,...
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In a nutshell These guidelines reviewed current best practices in treating male infertility. Some background Male infertility affects half of all couples with infertility. Low sperm count or quality are the most common signs of male infertility. Medical organizations offer guidelines on how to treat male infertility. Methods &...
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