In a nutshell This study investigated the use of progestogen (PTG) to prevent miscarriage in women with recurrent miscarriages (RM). They found that PTG reduces the chance of miscarriage in following pregnancies. Some background Pregnancy loss or miscarriage affects many women. Some women may experience several miscarriages, or recurrent miscarriages...
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Treating infertility: is letrozole more effective than clomiphene for patients with polycystic ovary syndrome?
In a nutshell This study investigated if letrozole (Femara) improves fertility outcomes in patients with polycystic ovary syndrome. They found that letrozole was not superior to clomiphene (Clomid) in treating infertility in these women. Some background Polycystic ovary syndrome (PCOS) is a condition that can lead to infertility. It is...
Read MoreVaccinations: recommendations for women seeking fertility treatment
In a nutshell This study reviewed the use of vaccinations for women seeking fertility. Some background Vaccinations are used to prevent developing certain diseases. In some cases, a woman seeking fertility treatment may not be vaccinated. Complications may arise if a woman is not fully vaccinated. There may be risks to both the mother and...
Read MorePreimplantation genetic testing for aneuploidy: can this technology improve IVF success?
In a nutshell This study investigated if a technology that detects chromosomal abnormalities (PGT-A) can improve in vitro fertilization (IVF) success. They found that this technology reduced the risk of failed embryo transfer and clinical miscarriage. Some background In vitro fertilization (IVF) is an assisted reproductive technology (ART). Eggs...
Read MoreWhat factors influence identical twin pregnancies following ART?
In a nutshell This study investigated factors affecting monozygotic twins (MZT) rates in patients undergoing fertility treatment. They found that embryo stage at transfer and higher embryos numbers increased the risk of MZT. Some background Monozygotic is the term used to describe identical twins. Monozygotic twins (MZT) occur when two embryos form...
Read MoreDiet and men’s fertility: does diet affect sperm quality?
In a nutshell This study reviewed dietary factors that may influence male fertility. Some background Male infertility is an increasing problem. In many cases, there is no obvious cause for male infertility. Some studies suggest that diet may play a role in this. Men that are overweight or obese are more likely to be infertile. The importance of a...
Read MoreDoes smoking have a negative effect on fertility?
In a nutshell This study reviewed the link between smoking and reduced fertility. Some background Smoking is not recommended for pregnant women. It is linked to a number of pregnancy complications. These include miscarriage, low birth weight, and premature labor. The effect of smoking on male and female fertility is less well understood. The American...
Read MoreTrigonella foenum-graecum and Lespedeza cuneata – a new herbal medicine to treat testosterone deficiency?
In a nutshell This study investigated if a mixed herbal extract of Trigonella foenum–graecum and Lespedeza cuneata (TFGL) could improve testosterone deficiency. They found that TFGL improved testosterone levels in men with testosterone deficiency. Some background Testosterone is a male sex hormone. It has a number of functions in the body....
Read MoreDoes the use of progestin in ovarian stimulation have any negative effects on infants born following IVF?
In a nutshell This study investigated if progestin-primed ovarian stimulation (PPOS) is associated with infant birth defects. They found that PPOS is not associated with negative outcomes in infants. Some background Assisted reproductive techniques (ART) include in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). In order to...
Read MoreDoes caffeine intake impact the success of fertility treatment?
In a nutshell This study investigated if caffeine intake affects the success of fertility treatment. They found that the outcome of fertility treatment was not associated with caffeine intake. Some background Caffeine is found in popular food and drinks such as coffee and chocolate. Caffeine causes you to feel alert and energized. It is unclear...
Read MoreDoes weight impact male fertility in couples undergoing assisted reproduction?
In a nutshell This study investigated if there is a link between male body mass index (BMI) and success of assisted reproductive treatment (ART). They found that high BMI in males is linked to reduced pregnancy and live birth rates in couples undergoing ART. Some background The causes of infertility in a couple are not always easily identified....
Read MoreDoes the Endometriosis Fertility Index (EFI) predict the likelihood of spontaneous pregnancy in women with infertility?
In a nutshell This study investigated if the Endometriosis Fertility Index (EFI) can predict if a woman will have a spontaneous pregnancy following endometriosis (EM) treatment. They found that EFI score accurately predicts if a patient will have a spontaneous pregnancy following treatment for EM. Some background Endometriosis (EM) is a condition...
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