In a nutshell This study compared how the thickness of the uterine lining affected outcomes from two protocols for in vitro fertilization (IVF). It found that the GnRH antagonist protocol had better outcomes when the lining was of medium thickness. The long GnRH agonist protocol had better outcomes when there was a thick lining. Some background IVF is...
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In a nutshell This review looked at whether genetic testing improved the birth rate from in vitro fertilization (IVF). It found that testing improved birth rates for women over age 35. Some background IVF is a common infertility treatment in which eggs are stimulated and collected, and fertilized embryos implanted back in the uterus. When IVF embryos...
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In a nutshell This study looked at which factors can predict pregnancy following in vitro fertilization (IVF) for patients with a poor ovarian response (POR). It found that pregnancy was affected by age, body weight, ovarian reserve, and type of fertility medication. Some background For couples with infertility, IVF can greatly increase the chances of...
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In a nutshell This study looked at how the Endometriosis Fertility Index (EFI) affected patients following endometriosis surgery. It found that patients with a better EFI score conceived naturally more often, while more patients with a low score became pregnant using assisted reproduction. Some background Endometriosis is a chronic condition in...
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In a nutshell This study compared two methods of preparing for frozen embryo transfer (FET) for women who do not ovulate regularly. It found that letrozole (Femara) led to fewer miscarriages and higher birth rates than hormone replacement therapy (HRT). Some background FET is an increasingly common infertility treatment. FET uses additional embryos...
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In a nutshell This review looked at insulin sensitivity (IS) and its impact in fertility for women with polycystic ovarian syndrome (PCOS). It found that improving IS led to higher pregnancy rates in these women. Some background PCOS is a collection of signs and symptoms that affects hormonal health and metabolism in women. PCOS often involves higher...
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In a nutshell This review looked at different hormonal methods to prepare the uterus for a frozen embryo transfer (FET). It found that cycles with ovulation led to better outcomes than an artificial cycle. Some background FET is an infertility treatment in which a frozen embryo is transferred into the uterus. The lining of the uterus needs to be...
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In a nutshell This study looked at how freezing affected sperm collected surgically from the testes. It found that frozen sperm and fresh sperm led to similar pregnancy rates from intracytoplasmic sperm injection (ICSI), but that there were more miscarriages when using frozen sperm. Some background Nonobstructive azoospermia (NOA) is a condition...
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In a nutshell This review looked at whether luteal phase support (LPS) using progesterone benefitted natural cycle frozen embryo transfers (FETs). It found that FETs with progesterone support had higher pregnancy and birth rates. Some background Frozen embryo transfer (FET) is an increasingly common infertility treatment. This technique transfers an...
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In a nutshell This study looked at how varicocele repair surgery affects the microscopic shape of sperm. It found that surgery improved sperm shape, movement, and concentration for men with infertility. Some background Varicoceles (VCs) can be a factor in male infertility. VCs are enlarged veins of the scrotum. These enlarged veins heat the testes,...
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In a nutshell This study looked at cholesterol and other lipid (fats) levels in the blood in women undergoing in vitro fertilization (IVF). It found that women with more heart-healthy lipid levels had better IVF outcomes. Some background Lipid levels are an important measure of health. While a lipid can be any oily or waxy substance in the body,...
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In a nutshell This study compared letrozole (Femara), clomiphene (Clomid), or no ovarian stimulation for women with polycystic ovarian syndrome (PCOS). It found that letrozole led to the uterus being more receptive to an embryo, and to higher pregnancy rates. Some background Women with PCOS do not ovulate frequently or at all. Patients who want...
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