In a nutshell This study investigated if progestin-primed ovarian stimulation (PPOS) is associated with infant birth defects. They found that PPOS is not associated with negative outcomes in infants. Some background Assisted reproductive techniques (ART) include in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). In order to...
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Does caffeine intake impact the success of fertility treatment?
In a nutshell This study investigated if caffeine intake affects the success of fertility treatment. They found that the outcome of fertility treatment was not associated with caffeine intake. Some background Caffeine is found in popular food and drinks such as coffee and chocolate. Caffeine causes you to feel alert and energized. It is unclear...
Read MoreDoes weight impact male fertility in couples undergoing assisted reproduction?
In a nutshell This study investigated if there is a link between male body mass index (BMI) and success of assisted reproductive treatment (ART). They found that high BMI in males is linked to reduced pregnancy and live birth rates in couples undergoing ART. Some background The causes of infertility in a couple are not always easily identified....
Read MoreDoes the Endometriosis Fertility Index (EFI) predict the likelihood of spontaneous pregnancy in women with infertility?
In a nutshell This study investigated if the Endometriosis Fertility Index (EFI) can predict if a woman will have a spontaneous pregnancy following endometriosis (EM) treatment. They found that EFI score accurately predicts if a patient will have a spontaneous pregnancy following treatment for EM. Some background Endometriosis (EM) is a condition...
Read MoreIs there a link between reduced sleep in men and difficulties in achieving pregnancy?
In a nutshell This study investigated if sleep duration in men can affect the chance of achieving pregnancy. They found that couples with men that slept less than 6 hours were less likely to achieve pregnancy. Some background Sleep is important for healthy living. Lack of sleep is associated with obesity, heart disease, and death. In the last few...
Read MoreIs preconception vitamin D deficiency associated with pregnancy loss?
In a nutshell This study investigated if there is a link between Vitamin D deficiency before conception and pregnancy loss. They found that sufficient preconception Vitamin D is associated with higher chances of pregnancy and live birth. Some background Vitamin D (Vit D) is an important nutrient for maintaining overall health. It may also be important...
Read MoreClinical Trials Today
Prior to the 20th century, most people lived about 47 years in the developed world because of infectious diseases. In 1940, the first use of penicillin to treat infectious diseases occurred and penicillin became available in 1945 to the general public. Science and research conducted throughout the 1950s, 60s, and 70s, created more antibiotics so that life...
Read MoreEvaluating the effect of myo-inositol supplementation on ovarian stimulation in women undergoing IVF
In a nutshell This study investigated if myo-inositol (MI) reduces the amount of gonadotrophins (GTs) needed for ovarian stimulation and the length of treatment in women undergoing in vitro fertilization (IVF). The results showed that MI reduced the amount of GTs needed and the duration of fertility treatment in these women. Some background...
Read MoreDoes treatment with dexamethasone improve IVF outcomes in patients with elevated progesterone?
In a nutshell This study investigated if dexamethasone (Ozurdex) improves the success of in vitro fertilization (IVF) in patients with elevated progesterone. They found that low-dose dexamethasone resulted in a higher birth rates following IVF. Some background During fertility treatment, women may undergo ovarian stimulation to...
Read MoreGnRH agonist vs. hCG: which is more effective to trigger ovulation in women with a history of follicular-endometrial asynchrony?
In a nutshell This study investigated the effects of GnRH agonist to stimulate ovulation in women with a history of follicular-endometrial asynchrony. They found that GnRH agonist was associated with higher rates of clinical pregnancy and live birth compared to standard hCG treatment. Some background One approach for treating unexplained...
Read MoreAntibiotic treatment for chronic endometritis: what are the effects on IVF success?
In a nutshell This study investigated if antibiotic treatment for endometritis affects the outcome of in vitro fertilization (IVF). They found that antibiotic treatment of CE improved IVF outcomes in patients who also experienced recurrent implantation failure. Some background Chronic endometritis (CE) is a condition caused by inflammation in the...
Read MoreGoing through IVF
The timetable around finding Mr. or Mrs. Right isn’t the same for everyone. My sister-in-law (who I will call S___ throughout this post) and her husband (H___) found each other when they were 41 and 49 respectively and didn’t marry until they were 44 and 52. They wanted children and tried for almost a year to do so but without success. S____...
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