In a nutshell This study compared the effectiveness of different intrauterine interventions for women with two or more implantation failures. The data showed that platelet-rich plasma (PRP) was the most effective intrauterine intervention in improving pregnancy outcomes in these women. Some background In vitro fertilization (IVF) is a widely used...
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In a nutshell The study compared the effectiveness of letrozole (Femara)/gonadotropin combination to letrozole alone in infertile women with polycystic ovarian syndrome (PCOS). The study found that the combination of letrozole/gonadotropin was more effective than letrozole alone in these women. Some background Polycystic ovarian syndrome or...
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In a nutshell This study evaluated the outcomes between in vitro fertilization (IVF) and non-IVF treatment after conservative surgery of advanced endometriosis (EM) in patients with a good Endometriosis Fertility Index (EFI) score. The data showed that both IVF and non-IVF treatments showed similar clinical pregnancy and live birth rates in these...
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In a nutshell This study evaluated whether fertility treatments increase the risk of breast cancer (BC) in women with a family history of BC or with BRCA mutations. The data showed that fertility treatments did not significantly increase the risk of BC in these women. Some background Treatment for infertility has become common, as people delay...
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In a nutshell This study evaluated the effects of acupuncture combined with metformin (Glucophage) versus metformin alone on pregnancy rate in women with polycystic ovary syndrome (PCOS). The data showed that acupuncture combined with metformin improved the pregnancy rate, ovulation rate, and insulin resistance compared with metformin treatment alone in...
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In a nutshell This study evaluated the clinical and cost-effectiveness of a luteinizing hormone (LH)-based modified gonadotrophin-releasing hormone (GnRH) antagonist protocol in patients with normal ovarian response undergoing in vitro fertilization (IVF) treatment. The data showed that the LH-based modified GnRH antagonist protocol was more...
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In a nutshell The study evaluated the effectiveness of injections of autologous endometrial cells (AEC) and platelet-rich plasma (PRP) in infertile women with a thin endometrium (uterine lining). The study found that PRP injections and injections of AEC suspended in PRP improved the cells and thickness of the endometrium. Some...
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In a nutshell This study evaluated the effectiveness and safety of two consecutive cycles of single embryo transfer (SET) versus one cycle of double embryo transfer (DET) in infertile women. The data showed that two consecutive cycles of SET significantly reduced the rate of multiple births, improved the maternal and neonatal side effects, and showed a...
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In a nutshell This study compared the effects of metformin (Glucophage) and exenatide (Byetta) on pregnancy rate and pregnancy outcomes in overweight or obese infertile women with polycystic ovary syndrome (PCOS). The data showed that 12 weeks of exenatide treatment before pregnancy improved spontaneous pregnancy in these women. Some background...
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In a nutshell This study evaluated the effectiveness of different ovarian stimulation protocols for patients with poor ovarian response (POR). The data showed that delayed start gonadotropin-releasing hormone (GnRH) antagonist and microdose GnRH agonist were the two most effective regimens for the treatment of these patients. Some background Many...
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In a nutshell This study evaluated whether hyaluronic acid gel (HAG) reduces intrauterine adhesions (IUAs) after curettage in women with a miscarriage. The data showed that HAG reduces the rate of IUAs in these women. Some background Up to a third of women who have a miscarriage need a dilation and curettage procedure for a miscarriage. A...
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In a nutshell The study compared the pregnancy rates for intrauterine insemination (IUI) and in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) in couples with unexplained infertility. The data concluded that IVF/ICSI is a better treatment option than IUI for unexplained infertility. Some background Infertility is the inability to...
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