In a nutshell This study investigated the effect of gonadotrophin-releasing hormone (GnRH) pulse therapy (PT) compared to human chorionic gonadotropin and human menopausal gonadotropin (HCG/HMG) combination therapy in men with hypogonadotropic hypogonadism (HH). They found that GnRH-PT stimulated sperm production earlier than other...
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Guizhi Fuling: a supplement to improve outcomes in women with endometriosis?
In a nutshell This study investigated if the Chinese herbal formula Guizhi Fuling capsule (GZFL) improves the outcomes of women with endometriosis (EDM) in combination with mifepristone (Mifeprex). They found that GF may improve EDM and pregnancy outcomes. Some background Endometriosis (EDM) is caused by tissue growing outside...
Read MoreIs low body mass index associated with semen quality?
In a nutshell This study investigated if body mass index (BMI) has an effect on semen quality. They found that low BMI is associated with reduced semen quality. Some background Male infertility is an increasing health problem. In many cases the cause of infertility is unknown. Lifestyle is one factor that may influence fertility. Body mass index...
Read MoreCoenzyme Q10 – can it improve sperm quality?
In a nutshell This study investigated if coenzyme Q10 (CoQ10) improves semen parameters in men with oligoasthenoteratozoospermia (OAT). They found that CoQ10 improved semen parameters in these men. Some background Male infertility can manifest as a number of symptoms. Men may have low hormone levels. They may produce a low number of sperm. The...
Read MoreBlastocyst number and pregnancy outcomes – what is the optimum for fertility success?
In a nutshell This study investigated if there is an association between blastocyst number (BCN) and pregnancy outcomes. They found that a BCN of up to 5 was associated with positive pregnancy outcomes. Some background In vitro fertilization (IVF) is a technique used to fertilise an egg in a laboratory. The fertilized embryo is allowed to...
Read MoreIVF outcomes in women with polycystic ovarian syndrome – are there increased risks?
In a nutshell This study investigated the outcomes of in vitro fertilization (IVF) pregnancies in women with polycystic ovarian syndrome (PCOS). They found that PCOS patients had a greater risk of complications after IVF. Some background Polycystic ovarian syndrome (PCOS) is a hormonal disorder that can lead to infertility. Women with PCOS may...
Read MoreDoes stress have an impact on IVF outcomes?
In a nutshell This study investigated if stress affects fertility outcomes (FOs) in patients undergoing in vitro fertilization (IVF). They found that stress does not have a negative effect on FOs. Some background Infertility affects many couples. Many infertile couples chose to undergo in vitro fertilization (IVF). Both...
Read MoreComparing the outcomes of two methods of embryo transfer
In a nutshell This study investigated the fertility outcomes (FOs) after transfer of vitrified-thawed cleavage embryos (VTCE). They found that VTCE was associated with positive and negative FOs. Some background Assisted reproductive technology (ART) is used to treat infertility. Initially, oocytes (eggs) are harvested and fertilized in a lab (in...
Read MoreStillbirth and advanced pregnancy age – is there an increased risk?
In a nutshell This study investigated if there is a link between gestational age (the number of weeks of pregnancy) and neonatal death (ND) or stillbirth (SB). They found that there was a greater risk of SB at 41 weeks. Some background Stillbirth (SB) continues to be an issue for many women. Although pregnancy care has improved vastly over the...
Read MoreOvarian response – what impact does this have on fertility success after IVF?
In a nutshell This study investigated if ovarian response (OR) has an effect on pregnancy outcomes in patients undergoing in vitro fertilization (IVF). They found that single embryo transfer (sET) in the blastocyst stage is preferred for all patients Some background In vitro fertilization (IVF) is a process that involves fertilizing an egg with sperm...
Read MoreSperm DNA fragmentation – a missing link to the cause of recurrent pregnancy loss?
In a nutshell This study investigated if sperm DNA fragmentation (sDF) is linked to a risk of recurrent pregnancy loss (RPL). They found that sDF is associated with RPL. Some background Infertility is a growing problem worldwide. Sometimes the cause of infertility can be determined and treated. In many cases, it is difficult to point out...
Read MoreWhat is the effect of abnormal insulin on fertility outcomes in polycystic ovarian syndrome?
In a nutshell This study investigated the effect of abnormal insulin responses (AIRs) on fertility outcomes in women with polycystic ovarian syndrome (PCOS). They found that AIRs can predict fertility outcomes in these patients. Some background Polycystic ovarian syndrome (PCOS) is a common cause of infertility. Cysts on the ovaries can...
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