In a nutshell This study investigated the risk of major adverse events in patients with coronary (CAD) or peripheral artery disease (PAD). They found that several factors could predict the risk of major adverse cardiac or limb events in CAD/PAD. Some background Coronary artery disease (CAD) is caused by reduced blood flow to the heart....
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Does body weight fluctuation increase the risk of heart disease and mortality?
In a nutshell This study investigated the effect of body weight changes on the risk of cardiovascular disease (CVD) and mortality. They found that body weight changes were associated with a higher risk of CVD and mortality. Some background Bodyweight fluctuation (BWF; weight changes) is common. Many people undergo BWF and it can be...
Read MoreOmega-3 Fatty Acids For the New Year!
I’ve been eating a load of holiday foods and thinking that I’m going to need to make some dietary adjustments. Like me, you may have read or heard in the news that clinical trials looking at omega-3 fatty acids (omega-3 acid ethyl esters – O3AEE) did NOT significantly reduce major cardiovascular events. In fact, the news may have said that...
Read MoreHow safe and effective is low-dose colchicine in preventing heart events after heart attack?
In a nutshell This study investigated the safety and effectiveness of low-dose colchicine (Colcrys) after a heart attack. They found that colchicine reduced the risk of ischemic cardiovascular events in these patients. Some background Coronary artery disease (CAD) is caused by reduced blood flow to the heart. Atherosclerosis (ATS)...
Read MoreDoes prior stroke affect ischemia or bleeding risk after percutaneous coronary intervention?
In a nutshell This study investigated the risk of ischemia (IR) or bleeding (BR) after stroke in patients undergoing percutaneous coronary intervention (PCI). They found that patients with prior stroke had higher IR/BR after PCI. Some background Coronary artery disease (CAD) is caused by blockages and reduced blood flow to the heart....
Read MoreCan hemoglobin levels predict clot or bleeding risk after percutaneous coronary intervention?
In a nutshell This study investigated if hemoglobin (Hb) levels can predict clotting or bleeding risk (CR/BR) after a percutaneous coronary intervention (PCI). They found that lower Hb was associated with higher CR/BR after PCI. Some background Coronary artery disease (CAD) is caused by reduced blood flow to the heart. Surgical procedures can be...
Read MoreEvaluating the effects of ranolazine, nicorandil and ivabradine in nonobstructive coronary artery disease
In a nutshell This study investigated the effects of ranolazine (Ranexa), nicorandil (Ikorel), and ivabradine (Corlanor) on angina. The main finding was that ranolazine and ivabradine reduced angina and nicorandil reduced microvascular resistance. Some background There are many drugs approved for the treatment of angina. These include ranolazine,...
Read MoreEvaluating the risk of bleeding with ticagrelor alone or with aspirin after percutaneous coronary intervention
In a nutshell This study investigated the effect of ticagrelor (Brilique) with or without aspirin on bleeding risk after a percutaneous coronary intervention (PCI). They found that ticagrelor alone reduced bleeding risk compared to ticagrelor + aspirin in these patients. Some background Coronary artery disease...
Read MoreDoes marine omega-3 supplementation decrease the risk of cardiovascular disease?
In a nutshell This study investigated whether marine omega-3 supplementation is associated with a reduction in the risk of cardiovascular disease (CVD). Researchers suggested that omega-3 is associated with a risk reduction of CVD. Some background CVD is the leading cause of death for both men and women in the US. It refers to conditions that involve...
Read MoreA review of 5-year outcomes after PCI or CABG intervention for left main coronary disease
In a nutshell This study investigated outcomes after 2 surgical interventions to treat coronary artery disease (CAD) in the left main artery. They found no difference in outcomes after percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) in these patients. Some background Coronary artery disease (CAD) is caused by...
Read MoreBiodegradable sirolimus versus durable everolimus stents – which is more effective after a heart attack?
In a nutshell This study investigated the effects of different drug-eluting stents (DES) in percutaneous coronary intervention (PCI) in patients who have had a heart attack. They found that biodegradable sirolimus (BS) stents were better than durable polymer everolimus (DPE) stents in improving blood flow. Some background Percutaneous...
Read MoreTicagrelor – is it effective in preventing major cardiac events in patients with diabetes and coronary artery disease?
In a nutshell This study investigated ticagrelor (Brilique) added to aspirin in patients with coronary artery disease (CAD) and diabetes mellitus (DM). They found that ticagrelor reduced the risk of cardiac events in these patients. Some background Patients with diabetes have a higher risk of ischemic events (IEs). IEs are caused by a lack...
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