In a nutshell This study looked at long-term treatment with ticagrelor (Brilique) after percutaneous coronary intervention (PCI) in patients with coronary artery disease (CAD). It found that compared to patients treated with placebo, those treated with ticagrelor were less likely to have a major cardiovascular event (MACE). Some...
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In a nutshell This study looked at the use of colchicine (Colcrys) in patients with coronary artery disease (CAD). It found that colchicine reduced the risk of heart attack and stroke in these patients. Some background CAD is a condition affecting the blood vessels in the heart. It leads to narrow or blocked blood vessels. It can...
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In a nutshell This study looked at the use of high-dose statin treatment before percutaneous coronary intervention (PCI) in patients with coronary artery disease (CAD). It found that patients who received high-dose statin treatment before PCI were less likely to have a major cardiovascular event (MACE) defined as a heart attack or stroke in the next...
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In a nutshell This study compared the Mediterranean diet (MD) with the low-fat diet (LFD) in patients with coronary artery disease (CAD). It found that after 3 months the MD was associated with higher omega-3 levels than the LFD. Some background Cholesterol is the name commonly used for the fats in the blood. Cholesterol can block the...
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In a nutshell This study looked at how beta-blockers affected patients following a heart attack. It found that patients using a low dose of beta-blockers had better outcomes one year later. Some background Following a heart attack, there are several treatment options available to improve outcomes. One treatment is beta-blockers (BBs), which prevent...
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In a nutshell This study evaluated whether antiplatelet therapy after percutaneous coronary intervention (PCI) should be given personalized for each patient. It found that guided therapy resulted in a reduction in the overall risk of heart attack, stroke, and death compared to standard therapy. Some background Percutaneous coronary...
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In a nutshell This study looked at which antiplatelet drug is better in patients who had percutaneous coronary intervention (PCI). It found that patients who had maintenance treatment with clopidogrel (Plavix) were less likely to suffer from a heart attack, bleeding, stroke, or death over the following 24 months compared to those...
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In a nutshell This study compared two heart interventions for people with coronary heart disease and type 2 diabetes (T2D). It found that coronary artery bypass grafting (CABG) led to better long-term outcomes than placing a stent in these patients. Some background Coronary heart disease (CHD) is a condition in which the arteries which supply blood to...
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In a nutshell This trial compared outcomes for sirolimus-eluting biodegradable stents (Orsiro) to everolimus-releasing durable stents (Xience) in patients with a need for more than 1 stent. It found that for patients having several stents placed after a heart attack, biodegradable stents had better outcomes. Some background While all heart...
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In a nutshell This study evaluated the long-term effects of rosuvastatin (Crestor) compared to placebo in reducing heart complications. This study concluded that rosuvastatin helped lower the risk of major cardiovascular events (MACE) in the long-term. Some background Most MACEs such as heart attack and stroke happen in people who do...
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In a nutshell This study looked at the use of the flu vaccine in patients with heart disease. It found that patients who had the flu vaccine were more likely to have better cardiovascular outcomes. Some background The flu can be especially dangerous for patients with heart disease. It can lead to further heart disease or even death. The...
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In a nutshell This study compared the treatment of stable ischemic heart disease (SIHD) with percutaneous coronary angioplasty (PCI) or with medication alone. It found that the risk of mortality was the same in both groups. Some background Coronary artery disease (CAD) is when the blood vessels in the heart become blocked and the heart muscle...
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