In a nutshell This study investigated the effects of changes in body mass index, or BMI (measurement of weight that takes height into account) and physical activity on mortality in people with coronary heart disease (CHD). It was determined that high levels of physical activity reduced the mortality risk. It was also found that weight loss increased the...
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Is a combination of rivaroxaban and aspirin better than either drug alone?
In a nutshell This study investigated the effects of combining rivaroxaban (Xarelto) with aspirin, compared to each drug used alone, in people with stable coronary artery disease. It was determined that the drug combination reduced the risk of stroke, heart attacks, and deaths from cardiovascular causes, more than aspirin alone, but that it increased the...
Read MoreRisk factors and treatment strategies in coronary heart disease
In a nutshell This study investigated risk factors and treatments in patients with coronary heart disease (CHD). It was determined that risk factors like smoking, obesity, and high blood pressure are common. It was also found that while use of medications was common, especially at early stages, people with CHD were unlikely to participate in a disease...
Read MoreDoes early treatment of heart attacks have long-term benefits?
In a nutshell This study compared the effects of early and delayed invasive treatment in people with heart attacks. It was determined that early invasive treatment reduced the risk of having another heart attack in the short term, but did not affect the risk of mortality or long-term risk of heart attacks, compared to delayed treatment. Some background...
Read MoreDoes the severity of angina affect the results of treatment?
In a nutshell This study investigated whether the severity of chest pain (angina) affects the impact of different treatments for stable coronary artery disease (CAD) in people with type 2 diabetes (T2D). It was determined that those with more severe angina were more likely to need revascularization (PCI or CABG), and to have severe angina after...
Read MoreIs angioplasty as safe as coronary artery bypass grafting?
In a nutshell This study compared percutaneous coronary intervention (PCI) using drug-eluting stents (DES) to coronary artery bypass grafting (CABG) in patients with left main coronary artery disease (LMCAD). The study concluded that PCI was associated with a higher risk needing another procedure and heart attacks, but not of death or stroke. Some...
Read MoreST-segment resolution after reperfusion therapy: can this predict the long-term effects of a heart attack?
In a nutshell This study investigated the long-term effects of ST-segment resolution after a heart attack. They concluded that Some background Coronary artery disease refers to blockages, or plaques, in vessels that supply blood to the heart. Following a heart attack (myocardial infarction), a procedure called reperfusion is performed. This...
Read MoreIs high dose pitavastatin better than low-dose?
In a nutshell This study compared the effects of treatment with high dose pitavastatin (Livalo) with low dose pitavastatin in Japanese adults with stable coronary artery disease (CAD). It was determined that high dose pitavastatin was more effective in preventing cardiovascular events than the low dose. Some background Pitavastatin is a type of drug...
Read MoreInvestigating microvascular function as a potential cause of angina in coronary artery disease.
In a nutshell This study investigated if the incidence of coronary microvascular dysfunction in patients with ischemic heart disease. They found that microvascular dysfunction is present in patients with angina. Some background Coronary arteries are responsible for supplying the heart with blood and oxygen. Coronary artery disease (CAD) is caused by a...
Read MoreAntioxidants in Grapes and Avocados
The mitochondria in cells produce energy. In the process they form reactive oxygen species. Reactive oxygen species, also called free radicals or oxygen radicals are used in many metabolic processes that are essential to life. For example, they are are part of enzyme reactions in the body. White blood cells, like neutrophils produce reactive oxygen...
Read More5 Things You Probably Didn’t Know About Your Adrenal Glands
The adrenal glands-which are also called suprarenal glands-are part of the endocrine system and are found on the top of each kidney. How the endocrine system hormones work Hormones secreted from glands of the endocrine system travel in the bloodstream to target cells. Target cells have receptors that are specific to each hormone. The hormones and receptors...
Read MoreIs ticagrelor effective in people with multi-vessel coronary artery disease?
In a nutshell This study examined the safety and effectiveness of ticagrelor (Brilinta) in patients with multi-vessel coronary disease (MVD) who had a previous heart attack. It was determined that ticagrelor reduced the risk of major adverse cardiac events (MACE), but increased the risk of certain types of bleeding. Some background Coronary...
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