In a nutshell This study compared the treatment of stable ischemic heart disease (SIHD) with percutaneous coronary angioplasty (PCI) or with medication alone. It found that the risk of mortality was the same in both groups. Some background Coronary artery disease (CAD) is when the blood vessels in the heart become blocked and the heart muscle...
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In a nutshell This study looked at the use of colchicine (Colcrys) in the treatment of coronary artery disease (CAD). It found that patients treated with colchicine had a lower risk of heart attack, stroke, or heart disease-related death. Some background CAD is a disease in which the blood vessels in the heart become blocked. It can...
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In a nutshell This study compared the rate and duration of COVID-19 infection in patients taking aspirin compared to those not taking this drug. They found that patients taking aspirin were less likely to get COVID-19 infection and had a lower duration of disease compared to those not taking aspirin. Some background Aspirin is...
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In a nutshell This study compared the use of two beta-blockers, carvedilol (Coreg) and metoprolol (Lopressor), after a heart attack. It found that they had similar results on most patient groups. However, carvedilol improved survival in patients with reduced heart function. Some background Beta-blockers are a group of medications that...
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In a nutshell This study looked at the risk of bleeding after percutaneous coronary intervention (PCI). It found patients who had chronic kidney disease, low body weight, diabetes, or who were aged over 80 were most likely to have bleeding problems. Some background Percutaneous coronary intervention (PCI) is a procedure commonly used to treat...
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In a nutshell This study compared several statin medications for the prevention of cardio-cerebrovascular (CCV) events such as strokes, heart attacks of death. It found that atorvastatin (Lipitor), pitavastatin (Livalo), rosuvastatin (Crestor), and simvastatin (Zocor) were all equally effective at preventing CCV...
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In a nutshell This study looked at the outcomes of patients treated with single or double long-term antiplatelet therapy (APT) after a percutaneous coronary intervention (PCI) using second-generation drug-eluting stents (DES). It found that single APT (SAPT) resulted in a lower risk of bleeding compared to dual APT (DAPT). Some...
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In a nutshell This study looked at the risk of heart attack or death in patients with chronic coronary disease (CAD) treated with revascularization procedures plus medication or medication alone. It found that revascularization procedures did not reduce the risk of death compared with medication alone, while coronary artery bypass grafting (CABG)...
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In a nutshell This study looked at the use of renin-angiotensin system (RAS) inhibitors after coronary artery bypass surgery (CABG). The study showed that RAS inhibitors are beneficial for all patients after CABG and reduce the risk of heart attack, stroke, or death. Some background CABG redirects blood around a section of a...
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In a nutshell This study compared the long-term safety and effectiveness of drug-coated balloons (DCB) and drug-eluting stents (DES) for the treatment of coronary artery disease (CAD). This study showed that DCB is as safe and effective as DES for treating small vessel CAD after three years of follow up. Some background Coronary artery disease...
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In a nutshell This study looked at giving 3 months or 12 months of dual antiplatelet medications following placement of a stent for patients with heart disease. It found that a shorter time on a dual regimen may lead to better outcomes than a longer period. Some background Coronary artery disease (CAD) occurs when the arteries leading to the...
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In a nutshell This study looked at the effectiveness of a combination of bempedoic acid (Nexletol) and ezetimibe (Ezetrol) in lowering cholesterol. It found that this treatment combination significantly lowered cholesterol levels. Some background High cholesterol is a major risk factor for heart attack and...
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