In a nutshell This study evaluated the effectiveness and safety of a shorter dual antiplatelet therapy (DAPT) duration after percutaneous coronary intervention (PCI) using drug-eluting stents (DES) in patients with acute or recent myocardial infarction (MI; heart attack) at high bleeding risk. The data showed that a shorter DAPT duration (1 month)...
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Comparing the long-term outcomes of percutaneous coronary intervention with everolimus-eluting stents versus coronary artery bypass grafting in patients with mutltivessel coronary artery disease.
In a nutshell This study compared the long-term outcomes of percutaneous coronary intervention (PCI) using everolimus (Afinitor)-eluting stents (Xience) versus coronary artery bypass grafting (CABG) in patients with multivessel coronary artery disease (CAD). The data showed that both treatments were associated with a similar risk of heart attack, stroke,...
Read MoreEvaluating the safety and effectiveness of different doses of asundexian in patients with acute myocardial infarction treated with dual antiplatelet therapy.
In a nutshell This study investigated the safety and effectiveness of different doses of asundexian (BAY 2433334) in patients with acute myocardial infarction (MI; heart attack) treated with dual antiplatelet therapy (DAPT). The data showed that asundexian 50 mg when added to DAPT inhibits blood clotting factor XIa by more than 90% without...
Read MoreEvaluating the effectiveness and safety of ivabradine in combination with beta-blockers in patients with stable angina.
In a nutshell This study evaluated the effectiveness and safety of ivabradine (Procoralan) in combination with beta-blockers in patients with stable angina. The data showed that the combination of ivabradine plus beta-blocker therapy effectively reduced heart rate, angina symptoms, and the use of short-acting nitrates from the first month of treatment...
Read MoreEvaluating the effect of patient-reported physical and mental health status before PCI/CABG on their long-term outcomes
In a nutshell This study evaluated the effect of patient-reported physical and mental health status before revascularization procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) on their long-term outcomes in patients with coronary artery disease (CAD). The data showed that...
Read MoreComparing the effectiveness and safety between biodegradable and durable polymer drug-eluting stents in patients with acute coronary syndrome.
In a nutshell This study compared the effectiveness and safety between biodegradable polymer (BP) drug-eluting stents (DES) and durable polymer (DP) DESs in patients with acute coronary syndrome (ACS). The data showed that both stent types demonstrated excellent effectiveness and safety after 1 year. The authors suggested that BP-DES may be more...
Read MoreCan icosapent ethyl prevent cardiovascular events and mortality in patients that have had previous heart attacks?
In a nutshell This study examined the effect of icosapent ethyl (IPE; Vascepa) on major cardiovascular events (MACEs) in statin-treated patients that had previous heart attacks (myocardial infarction; MI). The data showed that patients treated with IPE had large and significant reductions in MACEs. Some background Ischemic events are associated with a...
Read MoreComparing the effects of a Mediterranean versus a low-fat diet in the secondary prevention of cardiovascular events in patients with coronary artery disease.
In a nutshell This study compared the effects of a Mediterranean versus a low-fat diet in the secondary prevention of major cardiovascular events (MACE) in patients with established coronary artery disease (CAD). The data showed that in secondary prevention, the Mediterranean diet was more effective in preventing MACEs compared to a low-fat diet in...
Read MoreComparing the effectiveness and safety of an early versus a delayed invasive strategy in patients with non-ST elevation acute coronary syndrome.
In a nutshell This study compared the effectiveness and safety of an early and a delayed invasive strategy (IS) in patients with non-ST elevation acute coronary syndrome (NSTE-ACS). The data showed that there were no significant differences in the risk of death, heart attacks, stroke rates, major bleeding, or revascularization between early and delayed...
Read MoreComparing the effectiveness and safety of short-term versus long-term dual antiplatelet therapy after percutaneous coronary intervention in patients at high bleeding risk.
In a nutshell This study compared the effectiveness and safety of short-term versus long-term dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) using drug-eluting stents (DES) in patients at high bleeding risk. The data showed that short-term DAPT significantly reduced the risk of bleeding compared with long-term DAPT...
Read MoreComparing the effectiveness and safety of percutaneous coronary intervention versus coronary artery bypass grafting in patients with left main coronary artery disease.
In a nutshell This study compared the effectiveness and safety of percutaneous coronary intervention (PCI) using drug-eluting stents (DES) versus coronary artery bypass grafting (CABG) in patients with left main (LM) coronary artery disease (CAD). The data showed that both treatments were associated with a similar risk of heart attack, stroke, and death....
Read MoreEvaluating the effect of trimetazidine for the treatment of patients with ischemic heart disease who are not suitable for revascularization.
In a nutshell This study evaluated the effectiveness of trimetazidine (Vastarel) versus other anti-anginal drugs for the treatment of patients with ischemic heart disease (IHD) who are not suitable for revascularization. The data showed that trimetazidine improved walking time and angina attacks in these patients. Some background Coronary artery...
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