In a nutshell This study is searching for participants with advanced solid tumors including colorectal cancer to examine the safety and effectiveness of experimental drug avapritinib (AYVAKIT). The main outcomes to be measured are the response to treatment and side effects. This trial is being conducted in Texas, US. The details Some cancers grow as a...Read More
Colorectal cancer Posts on Medivizor
Can addition if oxaplatin to tegafur–uracil/leucovorin improve the outcome of patients with colorectal cancer?
In a nutshell The aim of this study was to evaluate the impact of adding oxaliplatin (Eloxatin) to the chemotherapy regimen tegafur uracil (UFT)/leucovorin (LV; folinic acid) for patients that had surgery for colorectal cancer (CRC). The study found that the addition of oxaliplatin to UFT/LV improved patient outcomes. Some background CRC can...Read More
In a nutshell The aim of this study was to compare the outcome of laparoscopic (keyhole surgery) and open surgery for patients with rectal cancer. The study found no difference in patient outcomes between laparoscopic and open surgery groups. Some background Localized rectal cancer can be treated by surgical removal of the tumor. Usually, patients...Read More
Survival of patients with rectal cancer followed-up by the watch and wait method after chemoradiotherapy
In a nutshell This study investigated the outcomes of patients with rectal cancer who were followed up with the watch and wait method after chemoradiotherapy (CRT). Researchers suggested that this strategy can effectively identify patients who can have a less frequent follow-up if they maintain response for the first 3 years...Read More
In a nutshell The aim of this study was to evaluate the urinary and sexual function of patients following 2 types of rectal cancer surgery. The study found that in men, robotic surgery resulted in better urinary and sexual function. Some background Rectal cancer can be treated by surgical removal of the tumor. Therapy for rectal cancer has improved...Read More
Does adding chemotherapy to cytoreductive surgery improve the outcome of patients with peritoneal metastases from colorectal cancer?
In a nutshell This study evaluated the benefit of adding hyperthermic intraperitoneal chemotherapy (HIPEC) to cytoreductive surgery (CS) for the treatment of colorectal cancer (CRC) that has spread to the peritoneum (the lining of the abdomen that covers all abdominal organs). The study found that HIPEC added to CS did not improve the outcomes of...Read More
High-dose rate intraoperative brachytherapy is associated with improved outcomes in patients with high-risk rectal cancer
In a nutshell This study compared the effectiveness of electron beam radiotherapy (EBR) and high-dose brachytherapy (HDB) during surgery in patients with rectal cancer who underwent an incomplete removal of the cancer. Researchers suggested that HDB was associated with a lower risk of recurrence in these patients. Some background Colorectal...Read More
Evaluating surgery and chemotherapy versus chemotherapy alone for the treatment of metastatic colorectal cancer.
In a nutshell This study evaluated whether surgery of colorectal cancer (CRC) followed by chemotherapy (CT) improved the outcomes of patients with metastatic (spread) CRC compared to CT alone. The study found that there was no difference in patients' outcomes whether surgery was given or not. Some background CRC is the third most common cancer...Read More
In a nutshell This study investigated the effectiveness and safety of computed tomography (CT)-guided radioactive 125Iodine (RI) implantation in patients with recurrent locally advanced rectal cancer (LARC). Researchers suggested that CT-guided RI implantation is a good and safe treatment for patients with LARC that came back...Read More
In a nutshell This study evaluated whether chemoradiotherapy (CRT) before surgery improves the outcomes of patients with stage II-III colorectal cancer (CRC). The study found that CRT before surgery may not be needed in certain patients with low-risk disease. Some background CRC is the third most common cancer worldwide. The standard therapy for...Read More
In a nutshell This study compared oncological adequateness (OA) and surgery outcomes between open and laparoscopic rectal cancer surgery. Researchers suggested that laparoscopic surgery (LS) is associated with good surgical and oncological outcomes. Some background Colorectal cancer is one of the most common cancers worldwide. Of these, 35% are rectal...Read More
Can reducing chemotherapy duration from 6 to 3 months reduce side effects in patients with colorectal cancer and still be effective?
In a nutshell This study investigated if reducing therapy duration could reduce side effects in patients but still be effective in patients with stage II colorectal cancer (CRC). This study showed that in certain patients a 3-month treatment duration can be considered. Some background Patients with colorectal cancer (CRC) can be treated...Read More