In a nutshell This study reported the long-term outcomes of catheter-based renal artery denervation (CB-RD) in patients with resistant or uncontrolled hypertension [high blood pressure (BP)]. The data showed that over the long-term CB-RD was safe and had significantly greater reductions in BP and better BP control compared with a sham control in these...
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Evaluating the effectiveness and safety of high-dose rosuvastatin combined with telmisartan or amlodipine on glucose metabolism in hypertensive patients with impaired fasting glucose.
In a nutshell This study evaluated the effectiveness and safety of high-dose rosuvastatin (Crestor) combined with telmisartan (Micardis) or amlodipine (Norvasc) on glucose metabolism in patients with atherosclerotic cardiovascular disease (ASCVD), hypertension (high blood pressure), and impaired fasting glucose (IFG or prediabetes). The...
Read MoreRecommendations for carbohydrate-restricted diets and intermittent fasting in patients with obesity, type 2 diabetes mellitus, and hypertension.
In a nutshell This study evaluated the effects of carbohydrate-restricted diets and intermittent fasting (IF) in patients with obesity, type 2 diabetes (T2D), and hypertension (high blood pressure). The authors recommended that in adults with T2D, overweight or obesity, a moderately-low carbohydrate diet can be considered as a dietary regimen for blood...
Read MoreEvaluating the association between omega-3 polyunsaturated fatty acids dosage and blood pressure in patients with hypertension.
In a nutshell This study evaluated the association between omega-3 polyunsaturated fatty acids (PUFA) dosage (amount of drug administered) and blood pressure (BP) in patients with hypertension (high BP). The data showed that the optimal combined intake of omega-3 fatty acids for lowering BP is likely between 2 g/day and 3 g/day in these...
Read MoreEvaluating the renin-angiotensin-aldosterone system inhibitors effects on mortality and disease severity in patients with COVID-19
In a nutshell This review analyzed the effect of renin-angiotensin-aldosterone system (RAAS) inhibitors including angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) on patient prognosis for COVID-19. The data suggested that there is no association between the use of ACEIs/ARBs and the risk of mortality and...
Read MoreEvaluating the benefits of a more versus a less intensive blood pressure lowering treatment strategy in patients with hypertension.
In a nutshell This study evaluated the benefits of a more versus a less intensive blood pressure (BP) lowering treatment strategy in patients with hypertension (high blood pressure). The data showed that a more intensive BP lowering treatment strategy significantly reduced the risks of stroke, heart failure, heart attacks, and cardiovascular death...
Read MoreIs there a long-term effect of weight loss surgery on major adverse cardiovascular events in patients with diabetes and hypertension?
In a nutshell This study evaluated the long-term relationship between bariatric surgery (BS; weight loss surgery) and major adverse cardiovascular events (MACE) in patients with obesity, diabetes, and hypertension (high blood pressure; BP). The study showed that a sustained decrease in MACE occurrence was associated with BS in these patients. Some...
Read MoreEvaluating the effects of using regular acetaminophen on blood pressure in patients with hypertension.
In a nutshell This study evaluated the effects of using regular acetaminophen (Paracetamol) on blood pressure (BP) in patients with hypertension (high BP). The data showed that regular daily acetaminophen use increased BP in these patients and increased the risk of cardiovascular disease when compared with placebo. Some background Hypertension or high...
Read MoreDo combination therapies given in fixed-doses polypills with aspirin reduce the risk of cardiovascular disease events?
In a nutshell This study investigated whether a combination pill given in fixed doses with or without aspirin can reduce the risk of cardiovascular disease events in patients without a previous history of cardiovascular disease. The data showed that a fixed-dose combination treatment strategy with aspirin significantly reduced the risks of...
Read MoreEvaluating the safety and effectiveness of a four-in-one blood pressure pill early-on in patients with hypertension.
In a nutshell This study investigated whether a single blood pressure (BP) pill containing 4 drugs (quadpill) at quarter doses is more effective than the standard dose of a single drug as initial treatment in patients with hypertension. The data showed that a quadpill was safe and more effective in getting BP under control than the standard...
Read MoreLifestyle changes for patients with high blood pressure resistant to medications
In a nutshell This study looked at the effects of diet and lifestyle changes for people with high blood pressure who did not respond to medication. It found that a four-month counseling program led to significant improvement in diet and exercise, blood pressure, and heart health. Some background Uncontrolled high blood pressure leads to cardiovascular...
Read MoreCan a salt substitute reduce the risk of a stroke and heart events in patients with high blood pressure?
In a nutshell This study investigated if a salt substitute could reduce the risk of stroke and cardiovascular (CV) events in patients with hypertension (high blood pressure). The data showed that the salt substitute reduced the risks of stroke, major CV events, and death from any cause compared to regular salt in patients with hypertension. Some...
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