In a nutshell This study evaluated the safety and effectiveness of talimogene laherparepvec (TVEC) therapy for patients with melanoma that cannot be surgically removed (unresectable). The study found that TVEC therapy is an effective treatment for these patients, with minimal side effects. Some background Patients with localized melanoma that is...
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TVEC therapy for patients with advanced stage melanoma
In a nutshell This study evaluated the safety and effectiveness of talimogene laherparepvec (TVEC) therapy for patients with melanoma that cannot be surgically removed (unresectable). The study found that TVEC therapy is an effective treatment for these patients, with minimal side effects. Some background Patients with localized melanoma that is...
Read MoreSurvival in patients with melanoma treated with pembrolizumab
In a nutshell This study wanted to find out what the survival rates are of patients with melanoma treated with pembrolizumab (Keytruda). The study found that after 5 years, there was a good response to treatment overall. Some background Pembrolizumab is a new cancer treatment. It treats many different types of cancer. It works by using the immune...
Read MoreOncolytic Virus Treatments
In 1904, a physician wrote about a patient with leukemia who went into remission when he got the flu. Though the patient was not cured, it was a ray of hope at a time when there were no treatments for leukemia. Other cases were reported throughout the years of people with Burkitt’s Lymphoma and Hodgkin’s Lymphoma going into remission when they...
Read MoreT-VEC treatment in patients with melanoma
In a nutshell This study wanted to find out how well a new cancer treatment called T-VEC works in patients with melanoma that cannot be surgically removed. The study found that this treatment is very effective in patients with melanoma that cannot be surgically removed. Some background T-VEC is short for talimogene laherparepvec. This is a new type of...
Read MoreComparing safety and effectiveness of treatments for advanced melanoma
In a nutshell This study wanted to look at the different types of treatment for melanoma, and find out which was best and had the least side effects. The study found that the best treatment was to use MEK inhibitors and BRAF, as it worked the best and had the least side effects. Some background There are a number of treatments available for melanoma...
Read MoreReal-world safety and effectiveness of BRAF inhibitors and anti-CTLA4 antibody in melanoma
In a nutshell This article investigated the safety and effectiveness of BRAF inhibitors like vemurafenib (Zelboraf) and dabrafenib (Tafinlar) and immunotherapy such as ipilimumab (Yervoy) in a real-world setting for patients with advanced melanoma. The authors concluded that this therapy is safe and...
Read MoreIsolated limb perfusion in patients with spreading melanoma
In a nutshell This study looked at the safety and effectiveness of repeated limb perfusion with anti-cancer drugs for patients with melanoma work. The study found that repeated limb perfusion is safe, and has a similar rate of success to the first time the limb was perfused. Some background Isolated limb perfusion (ILP) is a technique...
Read MoreIsolated limb perfusion in patients with spreading melanoma
In a nutshell This study looked at the safety and effectiveness of repeated limb perfusion with anti-cancer drugs for patients with melanoma work. The study found that repeated limb perfusion is safe, and has a similar rate of success to the first time the limb was perfused. Some background Isolated limb perfusion (ILP) is a technique...
Read MoreASCO’s National Cancer Opinion Survey Results
During July and early August of 2018, the Harris Poll in association with the American Society of Clinical Oncologists (ASCO’s) conducted a poll of 4,887 U.S. adults, 1001 of these have or had cancer. This second annual National Cancer Opinion Survey explored a wide range of topics. The findings clearly describe disparities in the care patients with...
Read MoreEvaluating epacadostat and pembrolizumab in patients with advanced melanoma
In a nutshell This article investigated the safety and effectiveness of epacadostat and pembrolizumab (Keytruda) for patients with advanced melanoma. The authors concluded that this therapy is safe and has encouraging effectiveness in these patients. Some background The immune system normally works to detect...
Read MoreTiredness in survivors of melanoma
In a nutshell This study wanted to find out if people who have survived having melanoma cancer have higher levels of tiredness (fatigue) compared to those who have not had cancer. The study found that the people who survived having melanoma who were under 40 years old had slightly higher levels of fatigue compared to the general population. Some...
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