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Searching for patients with EGFR-positive advanced tumors to trial an experimental treatment.

Searching for patients with EGFR-positive advanced tumors to trial an experimental treatment.

Posted by on Nov 22, 2020 in Melanoma | 0 comments

In a nutshell This trial is being carried out to assess the safety and effectiveness of an experimental drug called BCA101 alone and in combination with pembrolizumab (Keytruda) in advanced solid tumors that are EGFR-positive. The main outcomes to be measured are the occurrence of side effects and response to treatment. The details Advanced...

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Can tumor DNA in the blood predict how well patients with melanoma will respond to immune therapy?

Can tumor DNA in the blood predict how well patients with melanoma will respond to immune therapy?

Posted by on Nov 13, 2020 in Melanoma | 0 comments

In a nutshell This study looked at the role of circulating tumor DNA (ctDNA) in predicting treatment response in advanced melanoma. They found that in patients treated for the first time with immune treatment, patients with low ctDNA levels had a longer survival without cancer worsening. Some background Advanced melanoma describes melanoma...

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Do immune related side effects from immunotherapy affect survival of patients with advanced melanoma?

Do immune related side effects from immunotherapy affect survival of patients with advanced melanoma?

Posted by on Sep 30, 2020 in Melanoma | 0 comments

In a nutshell This study was carried out to assess whether immune related side effects (IRSE) of anti-PD1 therapy affect the survival of patients with advanced melanoma. The authors of this study found that patients who had IRSE had better outcomes. Some background Advanced melanoma is a form of skin cancer that comes from a cell called a...

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Can a combination of dabrafenib and trametinib improve relapse-free survival after removal of stage 3 melanoma?

Can a combination of dabrafenib and trametinib improve relapse-free survival after removal of stage 3 melanoma?

Posted by on Sep 24, 2020 in Melanoma | 0 comments

In a nutshell This study investigated the long-term effectiveness and risks of the combination of dabrafenib (Tafinlar) and trametinib (Mekinist) for patients with stage 3 melanoma after tumor removal. It showed that the combination of the two drugs can increase survival without return or spreading of cancer. Some...

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Can removal of metastasis improve overall survival in patients with melanoma who responded to targeted therapy?

Can removal of metastasis improve overall survival in patients with melanoma who responded to targeted therapy?

Posted by on Sep 19, 2020 in Melanoma | 0 comments

In a nutshell This study was carried out to assess the effectiveness of metastasectomy (ME; surgical removal of tumors that have spread from the original tumor location) for patients with advanced melanoma who responded to targeted or immunotherapy. The authors found that ME for melanoma is associated with a longer overall survival (OS) in...

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