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Melanoma Posts on Medivizor

Which treatment works best, nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone for advanced melanoma

Posted by on Nov 7, 2018 in Melanoma | 0 comments

In a nutshell This study wanted to find out which medications are better for treating advanced melanoma; nivolumab (Opdivo) plus ipilimumab (Yervoy), nivolumab alone, or ipilimumab alone. The study found that using the combination of nivolumab and ipilimumab was more effective than using nivolumab alone, with the least...

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Treatment for advanced melanoma with abnormal genes

Posted by on Nov 4, 2018 in Melanoma | 0 comments

In a nutshell This study wanted to find out which treatment for melanoma cancer worked better, encorafenib (Braftovi) + binimetinib (Mektovi), encorafenib alone, or vemurafenib (Zelboraf) alone. The study found that encorafenib + binimetinib worked well and was safe, compared to vemurafenib and encorafenib. Some background In about 50% of patients...

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Comparing newer drug treatments for late-stage melanoma

Posted by on Nov 3, 2018 in Melanoma | 0 comments

In a nutshell This study was looking at which combination of medication is better at treating late-stage melanoma, ziv-aflibercept (Zaltrap) combined with high-dose interleukin-2 (Proleukin) or high-dose interleukin-2 by itself. The study found that using ziv-aflibercept combined with high-dose interleukin-2 was better than using high-dose interleukin-2...

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TVEC as a treatment for advanced melanoma

Posted by on Oct 26, 2018 in Melanoma | 0 comments

In a nutshell This study analysed a treatment for late-stage melanoma called talimogene laherparepvec (TVEC). It found that treating late-stage melanoma with TVEC was effective, and had only minor side effects. Some background Talimogene laherparepvec (TVEC) (Imlygic) is a treatment used for late-stage melanoma which is unable to be operated on. TVEC...

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Pembrolizumab to treat advanced mucosal melanoma

Posted by on Oct 19, 2018 in Melanoma | 0 comments

In a nutshell This study wanted to find out if the drug pembrolizumab (Keytruda) is effective in treating mucosal melanoma. The study found that pembrolizumab had some effect on mucosal melanoma, and the overall survival of patients was 11 months. Some background Mucosal melanoma is a very aggressive type of cancer, with no specific treatment. Recent...

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Surgical treatment options for anal melanoma

Posted by on Oct 9, 2018 in Melanoma | 0 comments

In a nutshell This study compared the afety and effectiveness of two surgical treatments for anal melanoma. The study found that patients who had a local excision and patients who had an abdominoperineal resection had the same level of overall survival. Some background Anal melanoma is a very rare cancer. Two surgical options for treatment are...

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The effect of FDG-PET imaging on patients with melanoma treated with immunotherapy.

Posted by on Sep 28, 2018 in Melanoma | 0 comments

In a nutshell The study looked at the use of FDG-PET imaging to assess long-term outcomes of treatment in patients with melanoma. Researchers found that FDG-PET imaging may be useful in predicting long-term outcomes of treatment in these patients. Some background Treatment for melanoma has vastly improved in recent years. Immunotherapies have improved...

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Effect of cancer medications nivolumab and ipilimumab on melanoma which has spread to the brain

Posted by on Sep 15, 2018 in Melanoma | 0 comments

In a nutshell This study looked at two medications for treatment of melanoma, nivolumab (Opdivo) and ipilimumab (Yervoy), and analysed how well they worked in patients who have melanoma which has spread to the brain. The study found that the combination of nivolumab and ipilimumab had significant clinical benefit in patients with melanoma with brain...

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SD-101 and pembrolizumab treatment in advanced melanoma

Posted by on Sep 15, 2018 in Melanoma | 0 comments

In a nutshell This study analysed a new medication to treat advanced melanoma called SD-101. The study found that patients responded very well to injection of the medication directly into the tumor alongside a common medication called pembrolizumab (Keytruda), although this worked best in patients who had never been treated with pembrolizumab...

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