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Melanoma Posts on Medivizor

Can sentinel lymph node biopsy predict outcome in locally recurrent or in-transit melanomas?

Posted by on Jun 5, 2017 in Melanoma | 0 comments

In a nutshell This study investigated the role of sentinel node biopsy (SLNB) in locally recurrent (LR; when the cancer comes back) melanoma or in-transit (IT; spreads to a lymph vessel before it reaches the nearest lymph node) melanoma. Researchers suggested that SLNB should be performed in these patients. Some background The sentinel lymph node...

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Lactate dehydrogenase is an effective outcome predictive factor for melanoma treatment with PD-1 agents

Posted by on May 16, 2017 in Melanoma | 0 comments

In a nutshell This study investigated whether changes in lactate dehydrogenase (LDH) levels in the blood could predict treatment response to PD-1 agents. Researchers suggested that LDH could be a useful factor to predict treatment outcomes in patients with advanced melanoma.   Some background The use of PD-1 agents to treat melanoma is...

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Carbon-ion radiation therapy is a safe treatment option for head and neck melanomas

Posted by on May 8, 2017 in Melanoma | 0 comments

In a nutshell This study investigated the effectiveness and safety of carbon-ion radiation therapy (CRT) for mucosal melanoma of the head and neck. Researchers suggested that CRT is an important treatment option for these patients. Some background Mucosal head and neck melanomas account for roughly 1% of all melanomas. However, is typically...

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Predictive factors of vulvar melanoma outcomes

Posted by on Mar 25, 2017 in Melanoma | 0 comments

In a nutshell This study investigated the factors predictive of survival of patients with vulvar melanoma (VM). Researchers suggested that tumor thickness and mitotic rate (a measure of how fast cancer cells are dividing and growing) are strong predictors of VM outcomes.  Some background VM affects 1.08 to 1.36 per million women every year in...

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Smoking is associated with an increased risk of melanoma lymph node metastasis

Posted by on Mar 20, 2017 in Melanoma | 0 comments

In a nutshell This study investigated the association between smoking and the risk of melanoma lymph node metastasis (LNM; spread to the lymph nodes). Researchers suggested that smoking is associated with an increase in the risk of LNM in melanoma patients. Some background Smoking is a well-known cause of cancer. However, it does not appear to be...

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Vemurafenib is an effective treatment option for BRAF-mutant metastatic melanoma

Posted by on Mar 6, 2017 in Melanoma | 0 comments

In a nutshell This study examined the effectiveness and safety of vemurafenib (Zelboraf) as treatment for BRAF-mutant metastatic melanoma. Researchers concluded that vemurafenib is an effective treatment option for patients with BRAF-mutated melanoma and brain metastasis (BM; spread to the brain). Some background Over 40% of melanoma patients...

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Radiation therapy in melanoma: a review

Posted by on Feb 27, 2017 in Melanoma | 0 comments

In a nutshell This review explored the effects of radiation therapy (RT) to treat melanoma. Researchers suggested that RT is useful in high risk melanoma to prevent recurrence (when the cancer comes back), however without increasing survival. Some background RT has long been used as a treatment for skin cancer. New surgery methods and knowledge of...

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