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Multiple Myeloma Posts on Medivizor

How effective is whole-body MRI as an imaging technique for measuring treatment responses in patients with blood cancers?

How effective is whole-body MRI as an imaging technique for measuring treatment responses in patients with blood cancers?

Posted by on Sep 27, 2022 in Multiple Myeloma | 0 comments

In a nutshell This study assessed the accuracy of whole-body (WB) magnetic resonance imaging (MRI) in evaluating the treatment response of blood cancers. The data indicated that WB-MRI had a high diagnostic performance for assessing the treatment response of blood cancers and its addition was strongly linked to better diagnostic sensitivity. Some...

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Evaluating the long-term effectiveness and safety of injections under the skin of daratumumab versus intravenous infusions for patients with relapsed or refractory multiple myeloma.

Evaluating the long-term effectiveness and safety of injections under the skin of daratumumab versus intravenous infusions for patients with relapsed or refractory multiple myeloma.

Posted by on Sep 20, 2022 in Multiple Myeloma | 0 comments

In a nutshell This study reported the final effectiveness and safety of subcutaneous (SC) injections versus intravenous (IV) infusions of daratumumab (Darzalex) in patients with relapsed or refractory multiple myeloma (MM). The data showed that daratumumab SC injections were as effective and caused fewer side effects than IV infusions over the long term...

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Evaluating the effectiveness and safety outcomes of administering radiotherapy at the same time with DCEP salvage chemotherapy in patients with multiple myeloma.

Evaluating the effectiveness and safety outcomes of administering radiotherapy at the same time with DCEP salvage chemotherapy in patients with multiple myeloma.

Posted by on Sep 17, 2022 in Multiple Myeloma | 0 comments

In a nutshell This study investigated the effectiveness and safety outcomes of administering radiotherapy (RT) at the same time as DCEP salvage chemotherapy in patients with unresponsive multiple myeloma (MM). This study concluded that RT administered at the same time with DCEP salvage chemotherapy was effective and well-tolerated by most of the...

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Evaluating the effectiveness of daratumumab-containing regimens in patients with multiple myeloma who are unresponsive to lenalidomide maintenance therapy.

Evaluating the effectiveness of daratumumab-containing regimens in patients with multiple myeloma who are unresponsive to lenalidomide maintenance therapy.

Posted by on Sep 11, 2022 in Multiple Myeloma | 0 comments

In a nutshell This study evaluated the effectiveness of daratumumab (Darzalex)-containing regimens in patients with multiple myeloma (MM) unresponsive to lenalidomide (Revlimid) maintenance therapy. The data showed that daratumumab-containing therapies are effective regimens in these patients. Some background Multiple myeloma (MM) is a type...

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Evaluating the impact of immunetherapy on COVID-19 outcomes in patients with cancer.

Evaluating the impact of immunetherapy on COVID-19 outcomes in patients with cancer.

Posted by on Sep 1, 2022 in Multiple Myeloma | 0 comments

In a nutshell This study evaluated the impact of immune checkpoint inhibitors (ICIs) on COVID-19 outcomes in patients with cancer. The data showed that the use of ICI treatment before COVID-19 infection does not affect the disease severity or survival outcomes. This study supports the continued use of ICIs in cancer patients during the pandemic. Some...

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Evaluating response to SARS-CoV-2 vaccination in patients with blood cancers

Evaluating response to SARS-CoV-2 vaccination in patients with blood cancers

Posted by on Aug 26, 2022 in Multiple Myeloma | 0 comments

In a nutshell The study aimed to investigate the rate of response (seroconversion) to SARS-Cov-2 vaccination in patients with blood cancers. This study concluded that seroconversion rates in these patients were significantly lower than that of healthy controls.  Some background The severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2)...

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Evaluating the effectiveness of a second autologous hematopoietic cell transplantation performed with stem cells obtained after previous transplantation in patients with relapsed multiple myeloma.

Evaluating the effectiveness of a second autologous hematopoietic cell transplantation performed with stem cells obtained after previous transplantation in patients with relapsed multiple myeloma.

Posted by on Jul 16, 2022 in Multiple Myeloma | 0 comments

In a nutshell This study evaluated the effectiveness of salvage autologous hematopoietic cell transplantation (ASCT) performed with stem cells obtained after previous transplantation in patients with relapsed multiple myeloma (MM). The data showed that salvage ASCT performed with stem cells remobilized after previous transplantation is a good treatment...

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Evaluating the effectiveness and safety of isatuximab in combination with pomalidomide and low-dose dexamethasone for the treatment of patients with relapsed or refractory multiple myeloma.

Evaluating the effectiveness and safety of isatuximab in combination with pomalidomide and low-dose dexamethasone for the treatment of patients with relapsed or refractory multiple myeloma.

Posted by on Jun 26, 2022 in Multiple Myeloma | 0 comments

In a nutshell This study evaluated the long-term effectiveness and safety of isatuximab (Sarclisa) in combination with pomalidomide (Pomalyst) and low-dose dexamethasone (Decadron) (Pd) in previously treated patients with relapsed or refractory (r/r) multiple myeloma (MM). The data showed that isatuximab plus Pd combination significantly improved the...

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Evaluating the effectiveness and safety of etoposide combined with cytarabine plus G-CSF for stem cell mobilization in patients with multiple myeloma.

Evaluating the effectiveness and safety of etoposide combined with cytarabine plus G-CSF for stem cell mobilization in patients with multiple myeloma.

Posted by on May 31, 2022 in Multiple Myeloma | 0 comments

In a nutshell This study evaluated the effectiveness and safety of etoposide (Etopophos) combined with cytarabine (Cytosar-U) plus granulocyte colony-stimulating factor (G-CSF, Neupogen) in patients with multiple myeloma (MM) for stem cell mobilization. The data showed that etoposide combined with cytarabine plus G-CSF was safe and effective for the...

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Evaluating COVID-19 vaccination in immunocompromised patients with blood cancers

Evaluating COVID-19 vaccination in immunocompromised patients with blood cancers

Posted by on May 31, 2022 in Multiple Myeloma | 0 comments

In a nutshell The study aimed to investigate if immunocompromised patients with blood cancers benefit from COVID-19 vaccination. This study concluded that these patients should not be excluded from COVID-19 vaccination.  Some background Patients with blood cancers are at high risk for severe forms of COVID-19 disease due to lower immune...

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Evaluating the effectiveness and safety of an all-oral combination of ixazomib, lenalidomide, and dexamethasone in patients with newly diagnosed multiple myeloma undergoing stem cell transplantation.

Evaluating the effectiveness and safety of an all-oral combination of ixazomib, lenalidomide, and dexamethasone in patients with newly diagnosed multiple myeloma undergoing stem cell transplantation.

Posted by on May 8, 2022 in Multiple Myeloma | 0 comments

In a nutshell This study evaluated the effectiveness and safety of an all-oral combination of ixazomib (Ninlaro), lenalidomide (Revlimid), and dexamethasone (Decadron) in transplant-eligible patients with newly diagnosed multiple myeloma (MM). The data showed that this combination was effective with manageable side effects in these...

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Evaluating the effectiveness and safety of ixazomib-dexamethasone versus pomalidomide-dexamethasone combination for the treatment of patients with relapsed or refractory multiple myeloma.

Evaluating the effectiveness and safety of ixazomib-dexamethasone versus pomalidomide-dexamethasone combination for the treatment of patients with relapsed or refractory multiple myeloma.

Posted by on Apr 29, 2022 in Multiple Myeloma | 0 comments

In a nutshell This study evaluated the effectiveness and safety of ixazomib (Ninlaro)-dexamethasone (Decadron) (ixa-dex) versus pomalidomide (Pomalyst)-dexamethasone (pom-dex) combination for the treatment of patients with relapsed or refractory (r/r) multiple myeloma (MM). The data showed that ixa-dex was safe and as effective as pom-dex...

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