In a nutshell This study evaluated the safety and effectiveness of ixazomib (Ninlaro) given after a stem cell transplant for patients with multiple myeloma (MM). This study concluded that ixazomib maintenance therapy is effective for these patients, with manageable side effects. Some background Multiple myeloma is a type of cancer of the bone marrow...
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A combination of clarithromycin, pomalidomide and dexamethasone in patients with relapsed/unresponsive multiple myeloma
In a nutshell This study aimed to investigate the safety and effectiveness of a combination of clarithromycin, pomalidomide, and dexamethasone (the ClaPd regime) in patients with relapsed/unresponsive multiple myeloma who had been treated with lenalidomide. This study concluded that this combination is as effective as other currently used...
Read MoreThe use of new agents and the risk of infections in patients with multiple myeloma
In a nutshell This study aimed to investigate the use of newer agents and the risk of infections in patients with multiple myeloma. This study concluded that there is a high risk of these patients developing at least one infection during treatment. Some background Infections are a major cause of illness and death in patients with multiple...
Read MoreEvaluating a treatment combination for patients with newly diagnosed and relapsed multiple myeloma
In a nutshell This study aimed to investigate the combination D-VCd containing daratumumab (Darzalex), bortezomib (Velcade), cyclophosphamide (Cytoxan), and dexamethasone (Decadron) in patients with multiple myeloma. This study concluded that this combination was safe and effective for these patients. Some background...
Read MoreEvaluating treatment options for patients with multiple myeloma who cannot have a stem cell transplant
In a nutshell This study evaluated the effectiveness of several treatment combinations for patients with multiple myeloma (MM) who were not eligible for a stem cell transplant (SCT). This study found that DaraVMP and VMPT were the most effective treatments for these patients. Some background MM is a type of cancer of the bone marrow that can lead...
Read MoreEvaluating a new CAR-T cell therapy for patients with relapsed or refractory multiple myeloma
In a nutshell This study investigated the safety and effectiveness of a new chimeric antigen receptor (CAR) T cell therapy for relapsed or refractory (does not respond to treatment) multiple myeloma (MM). This study found that this cell therapy was effective, but it had significant side effects. Some background MM is a type of cancer of the...
Read MoreEvaluating carfilzomib plus dexamethasone for relapsed or refractory multiple myeloma
In a nutshell This study evaluated the impact of carfilzomib (Kyprolis) and dexamethasone (Decadron) on quality of life for patients with relapsed or refractory (does not respond to treatment) multiple myeloma (MM). This study concluded that patients treated with this combination had a higher quality of life. Some background MM is a...
Read MoreBortezomib plus lenalidomide for patients with multiple myeloma a after stem cell transplant
In a nutshell This study evaluated the safety and effectiveness of bortezomib (Velcade) and lenalidomide (Revlimid) for patients with multiple myeloma after stem cell transplantation. This study found this combination is effective for these patients, with few side effects. Some background Multiple myeloma (MM) is a type of cancer...
Read MoreBortezomib plus lenalidomide for patients with multiple myeloma a after stem cell transplant
In a nutshell This study evaluated the safety and effectiveness of bortezomib (Velcade) and lenalidomide (Revlimid) for patients with multiple myeloma after stem cell transplantation. This study found this combination is effective for these patients, with few side effects. Some background Multiple myeloma (MM) is a type of cancer...
Read MoreLenalidomide maintenance therapy after a stem cell transplant for multiple myeloma
In a nutshell This study evaluated the outcomes of maintenance therapy with lenalidomide (Revlimid) after autologous stem cell transplantation (ASCT) in patients with multiple myeloma (MM). This study concluded that longer lenalidomide maintenance leads to improved survival outcomes in these patients. Some background Multiple myeloma is a type of...
Read MoreOncolytic Virus Treatments
In 1904, a physician wrote about a patient with leukemia who went into remission when he got the flu. Though the patient was not cured, it was a ray of hope at a time when there were no treatments for leukemia. Other cases were reported throughout the years of people with Burkitt’s Lymphoma and Hodgkin’s Lymphoma going into remission when they...
Read MoreIs stem cell transplant more effective than other treatments for multiple myeloma?
In a nutshell This study compared the effects of stem cell transplant to other newer treatments for recently diagnosed multiple myeloma (MM). The main finding was patients who received stem cell transplant had better outcomes than those who did not. Some background Stem cell transplant involves the transfer of cells to a patient. This is an effective...
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