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Multiple Myeloma Posts on Medivizor

Early results of treatment with carfilzomib, pomalidomide, and dexamethazone for previously treated multiple myeloma

Posted by on Jun 14, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study examined the safety of combining a biologic therapy (pomalidomide [Pomalyst]), a targeted therapy (carfilzomib [Kyprolis]), and a steroid drug (dexamethasone [Decadron]) for relapsed or refractory multiple myeloma. Researchers reported early results on the safety and potential effectiveness of this treatment combination. Some...

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Recording symptom burden and palliative care concerns in multiple myeloma patients

Posted by on Jun 14, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study assessed symptom severity, quality of life and palliative care (treatment to relieve symptoms) concerns in multiple myeloma patients. Authors concluded that patients with multiple myeloma generally have a high symptom burden and low quality of life. Some background Multiple myeloma is the second most common type of blood...

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Multiple myeloma in older patients: Comparing treatment outcomes between fit and frail patients

Posted by on Jun 14, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study analyzed the results of 3 trials to examine treatment outcomes in frail older patients with multiple myeloma. Authors reported poorer treatment outcomes and a higher rate of side effects among elderly patients in poorer health. Some background Over 60% of multiple myeloma cases are diagnosed in individuals aged above 65...

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Recommendations for the management, treatment and care of myeloma patients not able to undergo stem cell transplantation

Posted by on Jun 6, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study reviewed the recommendations for the treatment and management of patients with multiple myeloma who are not able to undergo stem cell transplantation. Some background Multiple myeloma most frequently affects older patients. The standard treatment option is high-dose chemotherapy followed by stem cell transplantation (SCT)....

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Is carfilzomib effective with lenalidomide and dexamethasone in relapsed multiple myeloma?

Posted by on Jun 6, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study compared the effectiveness of carfilzomib (Kyprolis), lenalidomide (Revlimid), and dexamethasone (Ozurdex) to lenalidomide and dexamethasone alone in patients with relapsed multiple myeloma. This study concluded that the addition of carfilzomib improved outcomes. Some background Survival rates for multiple myeloma have...

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Comparing first-line treatment combinations with and without maintenance therapy

Posted by on Jun 6, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study compared first-line treatment options for multiple myeloma with and without maintenance therapy. Researchers reported superior treatment outcomes with high-dose melphalan (Alkeran) plus stem cell transplantation when compared to a combination of orally administered treatments. Additional maintenance therapy with lenalidomide...

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Continuous lenalidomide-dexamethasone treatment is effective for patients not eligible for stem cell transplantation

Posted by on May 30, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study examined the effectiveness of lenalidomide (Revlimid) and dexamethasone (Ozurdex) in treating patients with newly diagnosed multiple myeloma not eligible for a stem cell transplant. Authors reported superior treatment outcomes with continuous lenalidomide compared to 18 cycles of lenalidomide or...

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What is the most effective induction therapy for multiple myeloma patients preparing for stem cell transplantation?

Posted by on May 30, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study compared two induction therapy regimens before high-dose chemotherapy and stem cell (immature blood cell) transplantation (SCT) in patients with multiple myeloma. The authors concluded that the combination of bortezomib (Velcade), thalidomide (Thalomid), and dexamethasone (Ozurdex) was more effective than bortezomib,...

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Adding ixazomib to treatment improves outcomes for relapsed/refractory multiple myeloma

Posted by on May 29, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study examined the safety and effectiveness of ixazomib (Ninlaro) when added to the treatment of relapsed multiple myeloma. Researchers concluded that ixazomib was safe and effective at improving treatment outcomes for relapsed multiple myeloma. Some background The addition of biologic drugs to standard treatment regimens for...

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