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Multiple Myeloma Posts on Medivizor

Combining carfilzomib with cyclophosphamide and dexamethasone for newly diagnosed multiple myeloma

Posted by on Aug 7, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study examined the safety of combining carfilzomib (Kyprolis), cyclophosphamide (Cytoxan), and dexamethasone Decadron) for multiple myeloma. Researchers reported early results on the safety and potential effectiveness of this treatment combination. Some background Advances in first-line treatments have improved response and...

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Leukemia, CAR T-cell Therapy and Dr. Larry

Leukemia, CAR T-cell Therapy and Dr. Larry

Posted by on Jul 27, 2017 in Blog, Hodgkin's lymphoma, Leukemia, Lymphoma, Multiple Myeloma, Non-Hodgkin lymphoma | 0 comments

Marathons are grueling 26.2 mile treks.  The Boston Marathon is the oldest (started in 1897) and is one of the Marathon Majors (along with London, New York, Tokyo, Berlin and Chicago). Marathon Man Raising Money For LLS In 2001, at age 48,  family practitioner, Larry Saltzman ran his first marathon in Chicago.  That started a  13 marathon odyssey to...

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Pomalidomide is safe and effective for advanced multiple myeloma when combined with dexamethasone

Posted by on Jun 28, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study examined the safety and effectiveness of pomalidomide (Pomalyst) for multiple myeloma patients who have received multiple prior therapies. Researchers reported improved treatment outcomes when pomalidomide was combined with the steroid drug dexamethasone (Decadron) compared to pomalidomide alone. Some background Standard...

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Donor stem cells not recommended as part of tandem stem cell transplantation

Posted by on Jun 28, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study analyzed the results of 5 trials to compare tandem stem cell transplant combinations for newly diagnosed multiple myeloma. Researchers do not recommend a double stem cell transplant, where the stem cells for the first transplant are sourced from the patient and in the second are sourced from a donor.  Some background...

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Early results of treatment with carfilzomib, pomalidomide, and dexamethazone for previously treated multiple myeloma

Posted by on Jun 14, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study examined the safety of combining a biologic therapy (pomalidomide [Pomalyst]), a targeted therapy (carfilzomib [Kyprolis]), and a steroid drug (dexamethasone [Decadron]) for relapsed or refractory multiple myeloma. Researchers reported early results on the safety and potential effectiveness of this treatment combination. Some...

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Recording symptom burden and palliative care concerns in multiple myeloma patients

Posted by on Jun 14, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study assessed symptom severity, quality of life and palliative care (treatment to relieve symptoms) concerns in multiple myeloma patients. Authors concluded that patients with multiple myeloma generally have a high symptom burden and low quality of life. Some background Multiple myeloma is the second most common type of blood...

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Multiple myeloma in older patients: Comparing treatment outcomes between fit and frail patients

Posted by on Jun 14, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study analyzed the results of 3 trials to examine treatment outcomes in frail older patients with multiple myeloma. Authors reported poorer treatment outcomes and a higher rate of side effects among elderly patients in poorer health. Some background Over 60% of multiple myeloma cases are diagnosed in individuals aged above 65...

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Recommendations for the management, treatment and care of myeloma patients not able to undergo stem cell transplantation

Posted by on Jun 6, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study reviewed the recommendations for the treatment and management of patients with multiple myeloma who are not able to undergo stem cell transplantation. Some background Multiple myeloma most frequently affects older patients. The standard treatment option is high-dose chemotherapy followed by stem cell transplantation (SCT)....

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Is carfilzomib effective with lenalidomide and dexamethasone in relapsed multiple myeloma?

Posted by on Jun 6, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study compared the effectiveness of carfilzomib (Kyprolis), lenalidomide (Revlimid), and dexamethasone (Ozurdex) to lenalidomide and dexamethasone alone in patients with relapsed multiple myeloma. This study concluded that the addition of carfilzomib improved outcomes. Some background Survival rates for multiple myeloma have...

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Comparing first-line treatment combinations with and without maintenance therapy

Posted by on Jun 6, 2017 in Multiple Myeloma | 0 comments

In a nutshell This study compared first-line treatment options for multiple myeloma with and without maintenance therapy. Researchers reported superior treatment outcomes with high-dose melphalan (Alkeran) plus stem cell transplantation when compared to a combination of orally administered treatments. Additional maintenance therapy with lenalidomide...

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