In a nutshell This article investigated the safety and effectiveness of high-dose therapy with autologous stem cell transplantation (HDT-ASCT) and maintenance treatment (treatment meant to keep cancer from coming back) with lenalidomide (Revlimid) for patients with multiple myeloma. The authors concluded that this therapy is safe...
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Is Daratumumab added to bortezomib plus dexamethasone better in treating multiple myeloma?
In a nutshell This article investigated the safety and effectiveness of adding daratumumab (Darzalex) to bortezomib (Velcade) and dexamethasone (Decadron) for the treatment of relapsed or refractory (does not respond to treatment) multiple myeloma (RRMM). The authors concluded that the addition of daratumumab is safe and gave the greatest benefit to...
Read MoreHow does elotuzumab affect pain and quality of life in non-responsive multiple myeloma?
In a nutshell This study investigated the effects of adding elotuzumab to lenalidomide and dexamethasone to treat un-responsive multiple myeloma. The main finding was that patients treated with elotuzumab responded better to lenalidomide and dexamethasone. Some background Many patients respond well to treatment for multiple myeloma (MM). However some...
Read MoreThalidomide for Multiple Myeloma.
In a nutshell This study aimed to compare the long-term effects of thalidomide (Immunoprin) to those of classic anti-cancer drugs in patients with recently diagnosed multiple myeloma. Thalidomide appeared effective but many patients experienced side-effects that affected treatment. Some background Vincristine (Oncovin), doxorubicin...
Read MoreThe effects of stem cell transplant in Multiple Myeloma.
In a nutshell This study investigated the effects of stem cell transplant and anti-cancer drug treatment for Multiple Myeloma. Stem cell transplant appeared to increase survival in patients with Multiple Myeloma. Some background Multiple myeloma (MM) is a type of cancer in which red blood cells over produce antibodies. Stem cell transplant is a common...
Read MoreThe safety of elotuzumab, lenalidomide and dexamethasone in unresponsive multiple myeloma.
In a nutshell This paper compared the safety and effectiveness of elotuzumab (Empliciti) plus lenalidomide (Revlimid) and dexamethasone (Decadron) with lenalidomide and dexamethasone in unresponsive multiple myeloma. It was found that elotuzumab plus lenalidomide and dexamethasone was more effective than lenalidomide and dexamethasone alone. Some...
Read MoreThe effects of Len/Dex combination therapy in relapsed multiple myeloma.
In a nutshell This study investigated the effects of lenalidomide/dexamethasone (Revlimid/Dexasone) combination treatment in relapsed multiple myeloma. The main finding was that the type of relapse may predict how a patient responds to lenalidomide/dexamethasone treatment. Some background Common treatments for multiple myeloma (MM) include...
Read MoreWhat are the effects of hemodialysis in multiple myeloma?
In a nutshell This study investigated the outcomes of hemodialysis in patients with multiple myeloma. The main finding was that those who did not undergo hemodialysis had better survival than those who did. Some background Multiple myeloma (MM) is a type of cancer which affects the white blood cells which produce antibodies (proteins that fight...
Read More“Your Life Depends on Your Own Advocacy”
“Always trust your gut. Don’t leave your treatment in the hands of someone that you don’t trust or that does not seem like a team player. Yes, they are all smart—even brilliant—but read, read, read, and question them at every corner and challenge the standard of care. Exercise, healthy eating, learning the ropes of insurance, mediation/prayer...
Read MoreEvaluating the risk of developing acute myeloid leukemia or myelodysplastic syndrome after a stem cell transplant
In a nutshell This study evaluated the risk of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) development in patients with lymphoma and myeloma after an autologous stem cell transplant (autoSCT). This study concluded that this risk is quite high after autoSCT in these patients. Some background AML and MDS are known long-term...
Read MoreClinical Trials Today
Prior to the 20th century, most people lived about 47 years in the developed world because of infectious diseases. In 1940, the first use of penicillin to treat infectious diseases occurred and penicillin became available in 1945 to the general public. Science and research conducted throughout the 1950s, 60s, and 70s, created more antibiotics so that life...
Read MoreCancer Vaccines
When I think of vaccines, I think of the MMRV (measles, mumps, rubella and varicella) vaccines which help our bodies establish immunity against diseases that used to kill. Now, there are vaccines being created for cancer. The rise of cancer vaccines According to Dr. Nora Disis, an oncologist and researcher in cancer vaccines at the University of...
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