In a nutshell This study evaluated the safety and effectiveness of the herpes zoster vaccine (Shingrix) in patients with blood cancer who are receiving anti-cancer therapy. This study concluded that the Shingrix vaccine was effective in these patients, with manageable side effects. Some background Shingles is caused by a virus called herpes zoster....
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An update of sorafenib as a maintenance agent after stem cell transplant for acute myeloid leukemia
In a nutshell This study aimed to investigate if sorafenib (Nexavar) would be a suitable maintenance agent for patients with acute myeloid leukemia who received a stem cell transplant. This study concluded that sorafenib is a safe and effective maintenance agent in these patients. Some...
Read MoreLong-term risk of infections after treatment of childhood leukemia
In a nutshell This study aimed to compare the risk of infections after treatment completion for pediatric leukemia survivors and the general population. This study concluded that there was a significant association between history of leukemia therapy and increased risk of infections. Some background Infections are a common...
Read MoreNilotinib for patients with chronic phase chronic myeloid leukemia
In a nutshell This study aimed to investigate outcomes for patients with chronic-phase chronic myeloid leukemia who received nilotinib as a first-line treatment. This study concluded that nilotinib is a valuable treatment option for these patients. Some background Nilotinib (Tasigna) is a targeted therapy...
Read MoreOutcomes of elderly patients with chronic myeloid leukemia treated with imatinib
In a nutshell This study aimed to investigate treatment response and outcome for patients of 75 years and older with chronic myeloid leukemia treated with imatinib (Gleevec). This study concluded that imatinib is important in the frontline treatment of these patients. Some background...
Read MoreThe outcomes of stem cell transplant for patients with blast crisis chronic myeloid leukemia pretreated with tyrosine kinase inhibitors
In a nutshell This study aimed to investigate the outcomes of stem cell transplant in patients with blast crisis chronic myeloid leukemia who were pre-treated with tyrosine kinase inhibitors. This study concluded that the survival of these patients was strongly dependent on pretransplant remission status. Some background...
Read MoreOutcomes od BCR-ABL mutated chronic myeloid leukemia patients who have failed tyrosine kinase inhibitors
In a nutshell This study aimed to investigate the frequency of BCR-ABL kinase domain mutation detection and its prognostic significance in patients with chronic-phase chronic myeloid leukemia (CP-CML) treated with tyrosine kinase inhibitors (TKIs). This study concluded that early mutation detection and use of 2nd and...
Read MoreModified Berlin-Frankfurt-Münster regimen for patients with newly diagnosed acute lymphoblastic leukemia
In a nutshell This study aimed to investigate if a modified Berlin-Frankfurt-Münster (BFM) regimen would be a safe and effective method of treatment for adult patients with newly diagnosed acute lymphoblastic leukemia (ALL). This study concluded that this regimen is well tolerated and effective...
Read MoreDonor type for transplant in pediatric patients with acute lymphoblastic leukemia
In a nutshell This study aimed to investigate the impact of donor type for stem cell transplant in pediatric acute lymphoblastic leukemia patients. This study concluded that the outcomes of transplants from matched donor and HLA-identical sibling donors are similar. Some background...
Read MoreImmunoglobulin levels at diagnosis and outcomes of patients with chronic lymphocytic leukemia
In a nutshell This study aimed to investigate the relationship between immunoglobulin (Ig) levels and clinical outcomes in patients with chronic lymphocytic leukemia. This study concluded that levels of IgG and IgA at diagnosis are important prognostic markers for infection in these patients. Some background Immunoglobulins (Ig)...
Read MoreStem cell transplant after chimeric antigen receptor therapy in patients with acute lymphoblastic leukemia
In a nutshell This study aimed to investigate if stem cell transplantation (SCT) could improve the long-term prognosis of minimal residual disease negative complete remission (MRD-CR) patients with acute lymphocytic leukemia (ALL) after chimeric antigen receptor-modified (CAR) T-cell therapy. This study concluded that this...
Read MoreComparing outcomes in patients with chronic lymphocytic leukemia with detectable and undetectable minimal residual disease
In a nutshell This study aimed to compare the outcomes for patients with chronic lymphocytic leukemia who achieved detectable and undetectable minimal residual disease (MRD). This study concluded that patients with undetectable MRD had better outcomes than those with detectable MRD. Some background Minimal...
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