In a nutshell This study looked at the safety and effectiveness of ibrutinib (Imbruvica) added to bendamustine (Treanda) and rituximab (Rituxan) in the treatment of unresponsive chronic lymphocytic leukemia. Researchers found that this treatment improved survival in these patients. Some background Chronic lymphocytic leukemia (CLL) is a...
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The effect of ibrutinib on white blood cell count in CLL
In a nutshell This study wanted to look at the effect of ibrutinib (Imbruvica) on white cell count (immune cells) in patients with chronic lymphocytic leukemia. Researchers found that increases in white cell count during ibrutinib treatment were normal and did not indicate poor outcomes in these patients. Some background Chronic lymphocytic leukemia...
Read MoreEvaluating the safety and effectiveness of ponatinib for CML
In a nutshell The study looked at the safety and effectiveness of ponatinib (Iclusig) in the treatment of chronic myeloid leukemia (CML). Researchers found that ponatinib was safe and effective in previously treated patients with CML. Some background Chronic myeloid leukemia is a type of cancer of the bone marrow. This can lead to abnormal immune...
Read MoreDo ACE inhibitors help with anthracycline-induced cardiotoxicity in leukemia and lymphoma?
In a nutshell This study aimed to investigate if enalapril influences anthracycline-induced cardiotoxicity in children with leukemia and lymphoma. This study concluded that enalapril has a role in reducing anthracycline-induced cardiotoxicity in these patients. Some background Anthracyclines are a class of chemotherapy drugs that can be used for...
Read MoreThe safety and effectiveness of bosutinib in patients with chronic myeloid leukemia
In a nutshell This study looked at the safety and effectiveness of bosutinib (Bosulif) in the treatment of chronic myeloid leukemia (CML). Researchers found that bosutinib was effective in patients who have failed other similar drug treatments. Some background Chronic myeloid leukemia (CML) is a cancer of the bone marrow. This can lead to abnormal...
Read MoreStem cell transplant for high risk acute lymphoblastic leukemia
In a nutshell This study reviewed the evidence for stem cell transplantation (SCT) in patients with acute lymphoblastic leukemia (ALL). Researchers found that SCT is an effective treatment option in patients with high risk of ALL coming back. Matched donors or siblings are the preferred stem cell donors. Some background ALL is a cancer of the bone...
Read MoreWhole body vibration during chemotherapy for leukemia and lymphoma
In a nutshell This study examined the effectiveness of vibration therapy on patients receiving chemotherapy for leukemia and lymphoma. Researchers found that vibration therapy improved daily function in these patients. Some background Exercise is proven to be effective in improving outcomes of patients with cancer. Chemotherapy treatment can make...
Read MoreThe impact of tyrosine kinase inhibitors on the survival of patients with chronic myeloid leukemia
In a nutshell This study aimed to investigate the outcomes of patients with chronic myeloid leukemia who were treated with tyrosine kinase inhibitors. This study concluded that this treatment increased survival for new and older CML cases. Some background Imatinib (Gleevec) was the first tyrosine kinase inhibitor (TKI) used to treat chronic myeloid...
Read MoreAdding Lomustine to chemotherapy for acute myeloid leukemia for elderly patients
In a nutshell This study looked at the safety and effectiveness of adding lomustine (Gleostine) to chemotherapy in the treatment of acute myeloid leukemia in patients aged over 60. Researchers found that this treatment improved outcomes for elderly patients with AML. Some background Acute myeloid leukemia (AML) is a cancer of the bone marrow....
Read MoreAdding inotuzumab ozogamicin with or without blinatumomab to chemotherapy for ALL.
In a nutshell This study looked at the effectiveness of adding inotuzumab ozogamicin (Besponsa) and blinatumomab (Blincyto) to low-intensity chemotherapy in the treatment of ALL. Researchers found that this combination of treatment was effective in these patients. Some background Acute lymphoblastic leukemia (ALL) is a cancer of the bone marrow. This...
Read MoreUse of specific T-cells in the treatment of ALL
In a nutshell This study looked at the use of specific T-cells to treat acute lymphoblastic leukemia. Researchers found that using these cells was effective in the treatment of these patients. Some background Acute lymphoblastic leukemia (ALL) is a type of cancer of the bone marrow. This can lead to abnormal cells in the immune system. It is often...
Read MoreIs blinatumomab safe and effective in the treatment of ALL?
In a nutshell This study looked at the safety and effectiveness of blinatumomab (Blincyto) in the treatment of unresponsive acute lymphoblastic leukemia (ALL). Researchers found that blinatumomab was safe and effective in the treatment of these patients. Some background Acute lymphoblastic leukemia is a type of cancer of the bone marrow. This can lead...
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