In a nutshell This study examined the safety and effectiveness of osimertinib (Tagrisso) compared to other targeted therapies for advanced non-small cell lung cancer (NSCLC). The authors concluded that osimertinib improved patient survival. Some background NSCLC accounts for the majority of lung cancers. Some...Read More
Research Posts on Medivizor
Evaluating the combination of brentuximab vedotin and bendamustine in hard to treat Hodgkin lymphoma.
In a nutshell This study examined the safety and effectiveness of combining brentuximab vedotin (Adcetris) and bendamustine (Treanda) in patients with reoccurring or unresponsive Hodgkin lymphoma (HL). The authors concluded that this regimen shows promise in HL which is difficult to treat. Some...Read More
In a nutshell This study analyzed the health-related quality of life (HRQOL) in patients with metastatic castration-sensitive prostate cancer (MCSPC) after treatment with apalutamide (Erleada) and androgen deprivation therapy (ADT). The study found that apalutamide plus ADT was well tolerated and improved survival compared to ADT alone in these...Read More
The role of androgen deprivation therapy plus radiotherapy in the treatment of prostate cancer after prostate surgery
In a nutshell This study compared the safety and effectiveness of short-term androgen deprivation therapy (ADT) combined with radiotherapy (RT) in patients who underwent radical prostatectomy (RP). The main finding was that the combination of ADT and RT reduced the risk of recurrence and disease progression in these patients. Some background RP is...Read More
What factors predict blood-related side effects of tyrosine kinase inhibitors in chronic myeloid leukemia?
In a nutshell This study aimed to investigate the occurrence of hematological (blood-related) side effects in patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors. This study concluded that bone marrow fibrosis at diagnosis was a predictor of hematological side effects from tyrosine...Read More
In a nutshell This study aimed to investigate the effectiveness and safety of atezolizumab plus nab-paclitaxel in unresectable, locally advanced or metastatic triple-negative breast cancer. This study concluded that this combination had a benefit in patients with PD-L1 immune cell positive...Read More
In a nutshell This review aimed to summarize available data about the effectiveness of mindfulness-based interventions for cancer-related symptoms in cancer patients and survivors. This review concluded that mindfulness-based interventions can have a beneficial effect as an adjuvant therapy in these patients. Some background...Read More
In a nutshell This study evaluated the outcomes of patients with Hodgkin lymphoma (HL) after a first allogeneic hematopoietic stem cell transplant (allo-HSCT). This study concluded that allo-HSCT is promising for these patients, with low relapse rates. Some background Autologous (auto) HSCT is the usual next step for patients with HL that...Read More
In a nutshell This study evaluated the safety and effectiveness of high-dose cyclophosphamide (Cytoxan) for the treatment of relapsed or unresponsive non-Hodgkin’s lymphoma (NHL). This study concluded that high-dose cyclophosphamide was safe and effective for these patients. Some background Chemotherapy regimens remain a standard treatment...Read More
In a nutshell This study aimed to investigate ponatinib combined with conventional therapy in recurrent Philadelphia chromosome-positive central nervous system leukemia with a BCR-ABL T315I mutation after allogeneic hematopoietic stem cell transplant. This study concluded that ponatinib may be effective for these...Read More
In a nutshell This study looked at omega-3 fats and vitamin D supplements for couples undergoing in vitro fertilization (IVF). This study found that these added nutrients resulted in healthier embryos. Some background The diets of both men and women can affect fertility. Studies have found that diets high in vegetables and omega-3 fats may...Read More
In a nutshell This study looked at the impact of DHEA supplements on the outcomes of in vitro fertilization (IVF) in women over age 35. This study found that DHEA improved IVF outcomes for these women. Some background IVF is a standard treatment for infertility that uses hormones to stimulate the ovaries. Women who do not produce many...Read More