In a nutshell This study investigated if the response to rheumatoid arthritis (RA) treatment is worse in obese patients. They found that obese patients with RA have a worse clinical response than non-obese patients do. Some background Rheumatoid arthritis (RA) is an inflammatory condition. Fat tissue contains high levels of inflammatory chemicals....
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What signs predict a flare in rheumatoid arthritis?
In a nutshell This study investigated if there are factors that predict if a patient will have a flare in rheumatoid arthritis (RA). They found that patients with worse disease activity, functional disability, and quality of life were more likely to experience flares. Some background Rheumatoid arthritis (RA) is a chronic (long-term),...
Read MoreCan ultrasound of the joints predict remission in rheumatoid arthritis?
In a nutshell This study investigated if an ultrasound of the joints (musculoskeletal) can predict if remission can be achieved in patients with rheumatoid arthritis (RA). They found that ultrasound can predict if a patient with RA will achieve remission. Some background The aim of treatment for rheumatoid arthritis (RA) is to reduce disease activity....
Read MoreEvaluating predictors for poor methotrexate response in patients with rheumatoid arthritis: can co-treatment with adalimumab improve disease symptoms?
In a nutshell This study investigated if there are disease features that can predict if a patient with rheumatoid arthritis will respond well to methotrexate treatment. They found that higher disease activity at early stages of treatment predicted a poor treatment response in these patients. Some background Treatment of rheumatoid arthritis (RA)...
Read MoreClinical Trials Today
Prior to the 20th century, most people lived about 47 years in the developed world because of infectious diseases. In 1940, the first use of penicillin to treat infectious diseases occurred and penicillin became available in 1945 to the general public. Science and research conducted throughout the 1950s, 60s, and 70s, created more antibiotics so that life...
Read MoreIs fatigue common in patients with controlled rheumatoid arthritis?
In a nutshell This study investigated fatigue in patients with early-stage rheumatoid arthritis. They found that these patients commonly report fatigue and this was linked to higher depression and anxiety scores. Some background The aim of rheumatoid arthritis (RA) treatment is to reduce disease activity. To achieve this, a patient will be...
Read MoreStaying Up-To-Date on Rheumatoid Disease
When we posted, “What’s in a name? Rheumatoid Arthritis versus Rheumatoid Disease,”we featured Kelly Young, a mom on a crusade to change thinking about an autoimmune disease that attacks the connective tissue of joints and systemically attacks the organs of the body – rheumatoid disease. Rheumatoid disease (also known as rheumatoid...
Read MoreDoes tocilizumab treatment result in improved work productivity in patients with rheumatoid arthritis?
In a nutshell This study investigated whether tocilizumab (Actemra) treatment improves work productivity in patients with rheumatoid arthritis. They found that house workers treated with tocilizumab were more productive and better quality of life compared to patients taking synthetic disease-modifying drugs. Some background One of the...
Read MoreIs an infliximab biosimilar safe and effective for methotrexate-resistant rheumatoid arthritis?
In a nutshell This study investigated if an infliximab (Remicade) biosimilar is safe and effective to treat rheumatoid arthritis. They found that the infliximab biosimilar PF-06438179/GP1111 was similarly effective as standard infliximab and well tolerated. Some background Biosimilars are medicines that act in the same way as the original...
Read MoreAssessing the potential of certolizumab pegol treatment for moderate/severe rheumatoid arthritis: is it a matter of time?
In a nutshell This study investigated the timepoint at which certolizumab pegol treatment is effective in treating rheumatoid arthritis. They found that the effectiveness of certolizumab pegol treatment at 12 weeks predicts future treatment success at 52 weeks. Some background Certolizumab pegol (CZP) is a new biologic drug that blocks activity of...
Read MoreUpadacitinib: a safe and effective rheumatoid arthritis treatment for patients resistant to csDMARDs
In a nutshell This study investigated whether upadacitinib is a safe and effective treatment for unresponsive patients with rheumatoid arthritis (RA). They concluded that upadacitinib improved RA symptoms in combination with csDMARDs and was well tolerated. Some background ne type of medication used to treat rheumatoid arthritis...
Read MoreDo men with rheumatoid arthritis have an increased risk of osteoporosis?
In a nutshell This study investigated whether men with rheumatoid arthritis are at an increased risk of developing osteoporosis. They found that men with rheumatoid arthritis are twice as likely to develop osteoporosis compared to healthy individuals. Some background Treatment of rheumatoid arthritis (RA) involves medications...
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