In a nutshell This study investigated the mortality rates in patients with early rheumatoid arthritis (RA). They found that mortality rates were similar to the general population in these patients. Some background Rheumatoid arthritis (RA) is a long-term condition. It causes painful inflammation in the joints. To treat RA, patients take...
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Fatigue in rheumatoid arthritis: can behavioral therapy improve symptoms?
In a nutshell This study investigated if behavioral therapy improves fatigue in rheumatoid arthritis (RA). They found that behavioral therapy reduced fatigue in patients with RA. Some background Rheumatoid arthritis (RA) is a long-term condition caused by inflammation. It leads to painful swelling in the joints and disability. Fatigue (tiredness)...
Read MoreTofacitinib alone or in combination to treat rheumatoid arthritis: a safety update from clinical trials
In a nutshell This study investigated the safety of tofacitinib (TFB; Xeljanz) in the treatment of rheumatoid arthritis (RA). They found that patients taking TFB alone had a reduced risk of infections. Some background Rheumatoid arthritis (RA) is a chronic condition caused by inflammation. This leads to painful swelling in the joints and...
Read MoreExercise in juvenile idiopathic arthritis: can an 8-week program improve exercise capacity?
In a nutshell This study investigated if water-based exercise (WBE) improved exercise capacities (ECs) in juvenile idiopathic arthritis (JIA). They found that anaerobic exercise capacity (AnEC) was improved in patients with JIA. Some background Juvenile idiopathic arthritis (JIA) is a condition that affects children under the age of...
Read MorePredicting treatment success in early RA: can biomarkers predict methotrexate response?
In a nutshell This study investigated if biomarkers (BMs) can predict the response to methotrexate (MTX) in early rheumatoid arthritis (RA). They found that the level of BMs at baseline could predict the success of MTX treatment. Some background Rheumatoid arthritis (RA) is a condition caused by inflammation. This leads to painful swelling...
Read MoreReducing cardiovascular disease risk in rheumatoid arthritis: is treat-to-target the best approach?
In a nutshell This study investigated if a treat-to-target (TTT) approach reduces cardiovascular disease (CVD) risk in patients with rheumatoid arthritis (RA). They found that TTT reduced CVD risk in patients with RA over 5 years. Some background Rheumatoid arthritis (RA) is a chronic condition caused by inflammation. Patients with RA have...
Read MoreTNF inhibitors in early RA: do they improve long-term disease symptoms?
In a nutshell This study investigated if tumor necrosis factor inhibitors (TNFi) are effective as a first-line treatment of rheumatoid arthritis (RA). They found that patients treated first with TNFi had greater improvements in RA symptoms. Some background Rheumatoid arthritis (RA) is a chronic disease. It is caused by inflammation...
Read MoreSeasonal effects in rheumatoid arthritis: when is disease activity lowest?
In a nutshell This study investigated disease activity in patients with rheumatoid arthritis (RA) by season. They found that disease activity was lowest in fall and highest in spring. Some background Rheumatoid arthritis (RA) is a condition affecting the joints of the body. In RA, there is an excess of inflammation. This leads to painful swelling...
Read MoreIs vitamin D deficiency linked to disease activity in juvenile idiopathic arthritis?
In a nutshell This study investigated if vitamin D levels and disease activity are linked in juvenile idiopathic arthritis (JIA). They found that low vitamin D levels were associated with higher disease activity. Some background Juvenile idiopathic arthritis (JIA) is caused by inflammation in the joints. The cause of JIA is unknown. In JIA, the...
Read MoreWhat is the best strategy to achieve remission in juvenile idiopathic arthritis?
In a nutshell This study investigated three treatment strategies to achieve remission in patients with juvenile idiopathic arthritis (JIA). They found that all treatment strategies were effective in achieving remission in JIA. Some background Juvenile idiopathic arthritis (JIA) is caused by inflammation. It causes painful swelling in the joints...
Read MoreIntensive treatment – is this the most effective approach to achieving remission in rheumatoid arthritis?
In a nutshell This study investigated intensive treatment to achieve remission in rheumatoid arthritis (RA). They found that intensive treatment was effective at achieving remission. Some background Rheumatoid arthritis (RA) is a long-term condition. It is caused by painful inflammation in the joints. To treat RA, patients are prescribed drugs...
Read MoreIs it possible to maintain low disease activity in rheumatoid arthritis with low dose baricitinib?
In a nutshell This study investigated if reducing the dose of baricitinib (BCB; Olumiant) maintained low disease activity (LDA) in rheumatoid arthritis (RA). They found that a lower dose of BCB maintained LDA in some patients while the others could be rescued by switching to the original dose. Some background Rheumatoid...
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