In a nutshell This study investigated the effectiveness of methotrexate (MTX) versus tocilizumab (TCZ) in early rheumatoid arthritis (RA). They found that TCZ patients had a greater reduction in disease activity (DA). Some background Rheumatoid arthritis (RA) is a chronic condition. It is caused by excessive inflammation...
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Orofacial symptoms and dentofacial deformities in patients with juvenile idiopathic arthritis
In a nutshell This study investigated the rates of orofacial symptoms (OFS) and dentofacial deformities (DFD) in patients with juvenile idiopathic arthritis (JIA). They found that OFS and DFD rates were high in JIA. Some background Juvenile idiopathic arthritis (JIA) is an inflammatory condition that affects children. JIA leads to painful...
Read MoreBimekizumab and certolizumab pegol – is this treatment combination safe and effective in rheumatoid arthritis?
In a nutshell This study investigated if bimekizumab and certolizumab pegol (Cimzia) is a safe and effective treatment combination in rheumatoid arthritis (RA). They found that this treatment combination improved RA symptoms and was well tolerated. Some background Rheumatoid arthritis (RA) is a chronic inflammatory...
Read MoreMedication tapering in rheumatoid arthritis – what is the most effective strategy?
In a nutshell This study investigated the effectiveness of medication tapering strategies in rheumatoid arthritis (RA). They found that tapering synthetic or biologic drugs was similarly effective. Some background Rheumatoid arthritis (RA) is a long-term immune condition. It is caused by painful swelling in the joints. Disease-modifying...
Read MoreSwitching from adalimumab to baricitinib – what are the benefits for patients with rheumatoid arthritis?
In a nutshell This study investigated if switching from adalimumab (Humira) to baricitinib (Olumiant) improves rheumatoid arthritis (RA) symptoms. They found that baricitinib (BAR) improved clinical outcomes in these patients. Some background Rheumatoid arthritis (RA) is a chronic condition. It is caused by inflammation that leads to painful...
Read MoreAsthma in rheumatoid arthritis – is there an increased risk?
In a nutshell This study investigated if the risk of asthma is greater in patients with rheumatoid arthritis (RA). The authors found that RA was linked to an increased risk of asthma. Some background Rheumatoid arthritis (RA) is known as an auto-immune disease. This is because the immune system attacks healthy tissue in the joints....
Read MoreMuscle function in rheumatoid arthritis – does resistance training improve functionality in women?
In a nutshell This study investigated low load resistance training (LRT) to improve muscle function in women with rheumatoid arthritis (RA). They found that LRT improved muscle strength and function. Some background Rheumatoid arthritis (RA) is a long-term condition. It is caused by painful inflammation in the joints. It can also lead to...
Read MoreNamilumab – a safe and effective treatment for poor-responder patients with rheumatoid arthritis?
In a nutshell This study investigated if namilumab is an effective treatment for patients with rheumatoid arthritis (RA) with a poor response to other therapies. They found that namilumab improved RA symptoms and was well tolerated. Some background Rheumatoid arthritis (RA) is a condition caused by inflammation. This leads to painful...
Read MoreTreatment of eye disease in patients with juvenile idiopathic arthritis – a guideline.
In a nutshell This study reviewed the treatment of uveitis (a form of eye wall inflammation) in patients with juvenile idiopathic arthritis (JIA). Some background Juvenile idiopathic arthritis (JIA) is a condition caused by inflammation. It affects children and leads to painful swelling in the joints. Children with JIA may also develop uveitis....
Read MoreDoes denosumab reduce joint damage in patients with rheumatoid arthritis?
In a nutshell This study investigated the effectiveness of denosumab (Prolia) in rheumatoid arthritis (RA). They found that this treatment reduces joint damage and improves bone mineral density in these patients. Some background Rheumatoid arthritis (RA) is a long-term condition. Inflammation leads to painful swelling in the joints and joint...
Read MoreLong-term safety of tofacitinib in patients with rheumatoid arthritis
In a nutshell This study investigated the long-term safety of tofacitinib (Xelijanz) in rheumatoid arthritis (RA). They found that this treatment was effective and well tolerated by patients with RA. Some background Rheumatoid arthritis (RA) is caused by inflammation. It is an auto-immune disease. This means the body’s immune cells...
Read MoreSarilumab – a comparative review of the safety and effectiveness
In a nutshell This study investigated the safety and effectiveness of sarilumab (Kevzara) compared to other drugs in rheumatoid arthritis (RA). They found that sarilumab is similarly or more effective than other RA drugs. Some background Rheumatoid arthritis (RA) is a long-term condition. RA is caused by inflammation. Treating RA...
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