In a nutshell This study reviewed the treatment of uveitis (a form of eye wall inflammation) in patients with juvenile idiopathic arthritis (JIA). Some background Juvenile idiopathic arthritis (JIA) is a condition caused by inflammation. It affects children and leads to painful swelling in the joints. Children with JIA may also develop uveitis....
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Does denosumab reduce joint damage in patients with rheumatoid arthritis?
In a nutshell This study investigated the effectiveness of denosumab (Prolia) in rheumatoid arthritis (RA). They found that this treatment reduces joint damage and improves bone mineral density in these patients. Some background Rheumatoid arthritis (RA) is a long-term condition. Inflammation leads to painful swelling in the joints and joint...
Read MoreLong-term safety of tofacitinib in patients with rheumatoid arthritis
In a nutshell This study investigated the long-term safety of tofacitinib (Xelijanz) in rheumatoid arthritis (RA). They found that this treatment was effective and well tolerated by patients with RA. Some background Rheumatoid arthritis (RA) is caused by inflammation. It is an auto-immune disease. This means the body’s immune cells...
Read MoreSarilumab – a comparative review of the safety and effectiveness
In a nutshell This study investigated the safety and effectiveness of sarilumab (Kevzara) compared to other drugs in rheumatoid arthritis (RA). They found that sarilumab is similarly or more effective than other RA drugs. Some background Rheumatoid arthritis (RA) is a long-term condition. RA is caused by inflammation. Treating RA...
Read MoreLow white blood cells and tocilizumab: is there an increased infection risk in juvenile arthritis?
In a nutshell This study investigated if neutropenia (NP; a low number of white blood cells that fight off infections) increases the risk of infection in patients with juvenile idiopathic arthritis (JIA) taking tocilizumab (Actemra). They found that NP during tocilizumab treatment did not increase the risk of infections in these...
Read MoreSarilumab in rheumatoid arthritis – an update on safety and effectiveness
In a nutshell This study investigated the safety and effectiveness of sarilumab (Kevzara) added to methotrexate in rheumatoid arthritis (RA). They found that sarilumab was clinically effective and well-tolerated. Some background Rheumatoid arthritis (RA) is a long-term condition. It is caused by an excess of inflammation in the joints....
Read MoreDoes rheumatoid arthritis disease activity improve during pregnancy?
In a nutshell This study investigated if pregnancy affects rheumatoid arthritis (RA) symptoms. They found that disease activity improved during pregnancy. Some background RA is categorized as an auto-immune disease. These develop when the body’s immune system starts attacking healthy tissue. During pregnancy, the woman’s...
Read MoreSarilumab for rheumatoid arthritis: what is the patient impact?
In a nutshell This study investigated the effect of sarilumab (Kevzara) on the treatment of rheumatoid (RA). They found that sarilumab had a greater impact on patients’ lives compared to other treatments. Some background Rheumatoid arthritis (RA) is a long-term condition. Treatment involves taking medication to reduce inflammation....
Read MorecsDMARDs vs. TNF inhibitors: which is more cost effective in the treatment of rheumatoid arthritis?
In a nutshell This study investigated the cost-effectiveness of different approaches to treat rheumatoid arthritis. They found that csDMARDs are as effective as TNF inhibitors and cost less. Some background Treating rheumatoid arthritis (RA) involves reducing inflammation. Inflammation leads to painful swelling and joint damage....
Read MoreIs hydroxychloroquine an effective treatment for rheumatoid arthritis?
In a nutshell This study investigated if hydroxychloroquine (HCQ; Plaquenil) is an effective treatment in rheumatoid arthritis (RA). They found that combining HCQ with other RA drugs improves symptoms. Some background Rheumatoid arthritis (RA) is a long-term condition. It is caused by excessive inflammation in the joints. This leads to painful...
Read MoreEarly intervention and mortality risk – are there benefits for patients with rheumatoid arthritis?
In a nutshell This study investigated the mortality rates in patients with early rheumatoid arthritis (RA). They found that mortality rates were similar to the general population in these patients. Some background Rheumatoid arthritis (RA) is a long-term condition. It causes painful inflammation in the joints. To treat RA, patients take...
Read MoreFatigue in rheumatoid arthritis: can behavioral therapy improve symptoms?
In a nutshell This study investigated if behavioral therapy improves fatigue in rheumatoid arthritis (RA). They found that behavioral therapy reduced fatigue in patients with RA. Some background Rheumatoid arthritis (RA) is a long-term condition caused by inflammation. It leads to painful swelling in the joints and disability. Fatigue (tiredness)...
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