In a nutshell This study investigated the effect of bariatric surgery (BS; weight loss surgery) in patients with rheumatoid arthritis (RA). They found that BS was associated with lower disease activity in patients with RA and obesity. Some background Rheumatoid arthritis (RA) is a chronic condition. It is caused by excessive...
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Biologic monotherapy – which drug is the most effective option in biologic-naïve rheumatoid arthritis?
In a nutshell This study investigated which biologic drugs improve rheumatoid arthritis (RA) management in patients who have not taken biologic drugs before. They found that interleukin-6 receptor inhibitors (IL6-Ri) drugs are most effective as a monotherapy (MT; single drug treatment). Some background Rheumatoid arthritis (RA) is a...
Read MoreDoes vegetable and seafood intake affect disease activity in rheumatoid arthritis?
In a nutshell This study investigated the effect of vegetable and seafood intake in patients with rheumatoid arthritis (RA). They found that high vegetable and seafood intake may be associated with lower disease activity (LDA). Some background Rheumatoid arthritis (RA) is a chronic condition. It is caused by inflammation that leads to...
Read MoreAn update on recommendations for the management of rheumatoid arthritis
In a nutshell This study investigated recent developments in the management of rheumatoid arthritis (RA). Some background Rheumatoid arthritis (RA) is a chronic disease caused by inflammation. Inflammation causes painful swelling in the joints. Over time joint tissue degenerates and RA patients can become disabled. RA is treated with...
Read MoreHow does rheumatoid arthritis and its management affect the risk of falls and fractures?
In a nutshell This study investigated how rheumatoid arthritis (RA)and its treatment may affect bone mineral density (BMD). They found that RA was associated with a reduced BMD and an increased risk of falls and fractures. Some background Rheumatoid arthritis (RA) is a chronic condition caused by inflammation. This leads to painful...
Read MoreUpadacitinib – an update on patient-reported outcomes
In a nutshell This study investigated patient-reported outcomes (PROs) in patients taking upadacitinib (Rinvoq) to treat rheumatoid arthritis (RA). They found that this treatment improved the quality of life (QoL) in these patients. Some background Rheumatoid arthritis (RA) is a chronic condition. In RA, the immune system attacks...
Read MoreWhat are the benefits of dietary fiber in patients with rheumatoid arthritis?
In a nutshell This study investigated the effect of dietary fiber supplementation (DFS) in patients with rheumatoid arthritis (RA). They found that DFS may improve RA symptoms. Some background Rheumatoid arthritis (RA) is a condition caused by chronic inflammation. The immune system is overactive in RA. This causes pain and disability over time....
Read MoreIs there a greater cancer or infection risk with abatacept treatment for rheumatoid arthritis?
In a nutshell This study investigated the risk of infection and cancer with targeted disease-modifying anti-rheumatic drugs (tDMARDs). They found that the cancer risk is slightly higher with abatacept (Orencia) compared to other tDMARDs. Some background Rheumatoid arthritis (RA) is a long-term autoimmune condition. Excessive inflammation...
Read MoreComparing the safety and effectiveness of peficitinib doses in patients with rheumatoid arthritis
In a nutshell This study investigated the safety and effectiveness of different doses of peficitinib (Smyraf; PFC) in treating rheumatoid arthritis (RA). They found that PFC doses of 50 mg or higher were the most effective in these patients. Some background Rheumatoid arthritis (RA) is a chronic condition caused by inflammation....
Read MoreCan early MRI changes predict treatment response and disease progression in rheumatoid arthritis?
In a nutshell This study investigated if early changes in magnetic resonance imaging (MRI) can predict long-term response (LTR) to treatment in rheumatoid arthritis (RA). They found that MRI changes after 1 month of treatment can predict LTR to tofacitinib (Xeljanz). Some background Rheumatoid arthritis (RA) is caused by painful...
Read MoreSwitching to an etanercept biosimilar – an investigation of the safety and efficacy profile
In a nutshell This study investigated if switching from etanercept (Enbrel) to a biosimilar of etanercept (SDZ-ETN) is safe and effective in patients with rheumatoid arthritis (RA). They found that switching to SDZ-ETN from reference etanercept was safe and effective. Some background Rheumatoid arthritis (RA) is a long-term...
Read MorePeficitinib in rheumatoid arthritis: is it safe and effective?
In a nutshell This study investigated the safety and effectiveness of peficitinib (Smyraf) in rheumatoid arthritis (RA). They found that peficitinib improved RA symptoms and slowed joint damage. Some background Rheumatoid arthritis (RA) is caused by inflammation in the joints. This is very painful and leads to joint damage....
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