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Posted by on Nov 19, 2016 in Hypertension | 0 comments

In a nutshell

This study examined the link between hypertensive disorders during pregnancy and cardiovascular disease mortality risk (death from stroke or heart disease). The authors concluded that women with a history of hypertension during pregnancy are at an increased risk of future cardiovascular mortality. 

Some background

Some women experience hypertensive disorders during pregnancy (HDP). There are different types and severities of hypertension during pregnancy. Gestational hypertension develops after 20 weeks of pregnancy. Preeclampsia or eclampsia is hypertension that occurs during pregnancy with increased protein in the urine. There is evidence to suggest that these conditions can lead to long-term cardiovascular problems such as heart disease, stroke and death. Cardiovascular disease (CVD) is a common cause of death and identifying risk factors for CVD could help in appropriate treatment selection early on.

Methods & findings

Records were collected from 31,656 women who gave birth in the same hospital. 14% of these women had experienced HDP. Mortality rates were compared over a study period of 20 to 29 years.

A total of 651 deaths were recorded during the study period. Of these, 20% of women had experienced HDP. Women with HDP were 56% more likely to die from a cardiovascular-related illnesses than non-hypertensive women.
Mortality risk increased two-fold for women who experienced HDP in more than one pregnancy compared to women with HDP in one pregnancy. 
 
Age at delivery, duration of the pregnancy, smoking status and type of HDP were not associated with increased mortality.

The bottom line

The authors concluded that women who experience HDP are at a greater risk of dying from a cardiovascular-related illnesses than those who do not. 

The fine print

Since the study only recorded 129 deaths in women with HDP, larger studies are needed to confirm these findings.

What’s next?

Consult with your physician to discuss possible screening and intervention methods for hypertensive disorders of pregnancy.  

Published By :

American Journal of Obstetrics & Gynecology

Date :

Dec 28, 2015

Original Title :

Hypertension in pregnancy and long term cardiovascular mortality: a retrospective cohort study.

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