In a nutshell This study assessed the effectiveness and safety of adding metformin (Glucophage) to insulin therapy in the treatment of adolescents with type 1 diabetes (T1D). The study showed that the use of metformin in these patients resulted in improved blood glucose control and body mass index (BMI) with an increased risk of...
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In a nutshell This study investigated the link between sodium-glucose cotransporter 2 inhibitors (SGLT2is) and eye (ocular) diseases in patients with type 2 diabetes (T2D). The data showed that there was no link between the occurrence of eye diseases and SGLT2is in these patients. Some SGLT2is such as ertugliflozin (Steglatro) and empagliflozin...
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In a nutshell This study evaluated the effects of carbohydrate-restricted diets and intermittent fasting (IF) in patients with obesity, type 2 diabetes (T2D), and hypertension (high blood pressure). The authors recommended that in adults with T2D, overweight or obesity, a moderately-low carbohydrate diet can be considered as a dietary...
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In a nutshell This study evaluated the effectiveness of combining low-intensity extracorporeal shock wave therapy (Li-ESWT) with a vacuum erectile device (VED) for the treatment of patients with diabetes mellitus (DM) and erectile dysfunction (ED) who were unresponsive to phosphodiesterase-5 (PDE5) inhibitors. The data showed that Li-ESWT combined with...
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In a nutshell This study assessed the effectiveness and safety of adding dorzagliatin (HMS552) to metformin therapy in patients with type 2 diabetes (T2D) with inadequately controlled blood glucose (sugar) while using metformin (Glucophage) alone. The data showed effective blood glucose control, good tolerance, and safety in patients...
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In a nutshell This study evaluated the effectiveness and long-term safety of dorzagliatin in patients with type 2 diabetes (T2D) without previous antidiabetic treatment. The authors concluded that dorzagliatin blood glucose (sugar) levels with no serious side effects in these patients. Some background Glucokinase is a...
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In a nutshell This study investigated the effects of foot-ankle therapeutic exercises on daily physical activity and gait (walking) speed in people with diabetic peripheral neuropathy (DPN). The data showed that at 12 weeks, these exercises led to improvements in fast walking speeds and quality of life compared to usual care. Some background...
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In a nutshell This study analyzed the safety and effectiveness of dapagliflozin (Farxiga) in patients with type 2 diabetes (T2D) across different ranges of baseline systolic blood pressure (SBP; blood pressure when the heart beats). The data suggested that dapagliflozin reduced the risk of hospitalization for heart failure (HHF) and kidney-related...
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In a nutshell This study evaluated the effectiveness and safety of low-intensity extracorporeal shock wave therapy (Li-ESWT) for patients with diabetes and erectile dysfunction (ED). The data showed that Li-ESWT was safe and effective in improving the symptoms of ED in these patients. Some background Erectile dysfunction (ED) consists of the inability...
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Are you ever skeptical when you see drug claims? One of my first questions when I read about a new drug or a statistic of some kind is: How do they know that? When I read about two new weight loss drugs presented at the European Association for the Study of Diabetes (EASD) in Stockholm, Sweden (19-23 Sept), my antennae went up. Here’s the story. Drug...
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In a nutshell This study evaluated the long-term effects of non-pharmacological (non-drug) interventions on diabetes and chronic complication outcomes in patients with high blood glucose (hyperglycemia) levels. The data showed that non-pharmacological interventions have a long-term effect on reducing diabetes occurrence among prediabetic patients...
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In a nutshell This study evaluated the effectiveness of panretinal photocoagulation (PRP) plus intravitreal anti-VEGF treatment versus PRP alone for the treatment of patients with diabetic retinopathy (DR; diabetic eye disease). The data showed that PRP with anti-VEGF combination treatment improved vision without an increase in side effects...
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