In a nutshell This study assessed the effectiveness and safety of eplerenone (Inspra) treatment for diabetic nephropathy (DN; diabetic kidney disease) in patients with type 2 diabetes (T2D). The data showed that eplerenone can be an effective supplement to existing clinical treatment in patients with DN. Some background DN is kidney damage...
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In a nutshell This study compared the effectiveness and safety of teneligliptin (Tenelia) to placebo in patients with type 2 diabetes (T2D) that was inadequately controlled with triple oral antidiabetic drugs (OADs). The study showed that teneligliptin may be considered as a fourth add-on OAD treatment in these patients. Some background T2D is...
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In a nutshell This study evaluated the effectiveness, durability, and safety of faricimab (Vabysmo) for the treatment of patients with diabetic macular edema (DME). The data showed that faricimab with extended dosing up to every 16 weeks was safe and showed good vision gains and clinical improvements in these patients. Some background...
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In a nutshell This study compared the effects of a ketogenic diet mobile health application (Keyto app) with breath acetone biofeedback (device) versus a calorie-restricted, low-fat diet (WW; weight watchers) app on weight loss and metabolic risk in patients with overweight or obesity. The data showed that a ketogenic diet app with a breath acetone...
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In a nutshell This study assessed the effects of canagliflozin (Invokana) therapy on body composition, glucose control, insulin resistance, and systemic (whole body) inflammation in patients with newly-diagnosed type 2 diabetes (T2D) compared to metformin (Glucophage). The data showed that canagliflozin therapy reduced visceral fat tissue, and...
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In a nutshell This study reviewed the effect of diabetes on lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH). The data suggested that LUTS were increased in patients with BPH that had diabetes compared to patients without diabetes. Some background Men above 50 years of age frequently experience LUTS due to...
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In a nutshell This study determined the effect of varying carbohydrate and saturated fat dietary contents on cardiovascular disease (CVD) risk factors during weight-loss maintenance. The authors concluded that restriction of carbohydrates provided improved insulin resistance on lipoprotein metabolism, without unwanted side effects on low-density...
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In a nutshell This study observed the effectiveness of a ketogenic diet (KD) in patients newly diagnosed with type 2 diabetes (T2D) that were overweight or obese. The authors concluded that a DK can control body weight, blood glucose, and blood lipids (fats) in these patients but long-term adherence is a challenge. Some background...
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In a nutshell This study assessed the safety and effectiveness of oral, high-dose daily vitamin D3 for the prevention of diabetes in adults at high risk for type 2 diabetes (T2D). The authors concluded that oral, high-dose daily vitamin D3 at a dose of 4000 IU was safe and well-tolerated in patients with prediabetes that were overweight or...
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Diabetes is complex. Many factors influence your risk of developing diabetes, including race. The way race is associated with diabetes risk may change the way physicians screen patients for the disease. Size Being overweight has been identified as a factor in diabetes, and may serve as a cue for screening. The United States Preventive Services...
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In a nutshell This study assessed the link between metformin (Glucophage) use in hospitalized and non-hospitalized patients with diabetes and different outcomes due to coronavirus disease 2019 (COVID-19). The study showed that metformin use was associated with a protective effect in COVID-19 outcomes in patients with type 2 diabetes (T2D). Some...
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In a nutshell This study evaluated the long-term relationship between bariatric surgery (BS; weight loss surgery) and major adverse cardiovascular events (MACE) in patients with obesity, diabetes, and hypertension (high blood pressure; BP). The study showed that a sustained decrease in MACE occurrence was associated with BS in...
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