In a nutshell This study set out to evaluate heart function in patients who received traustuzumab with anthracycline and taxane–based chemotherapy. This study concluded that, in patients without heart disease at baseline, adding traustuzumab to adjuvant anthracycline and taxane–based...
Read MoreIn a nutshell This trial aims to evaluate the use of omega-3 fatty acid supplements to prevent side effects caused by aromatase inhibitors. Aromatase inhibitors can cause arthralgia (bone and joint pain). The main outcomes to be investigated are the change in pain score and the change in joint symptoms. This trial is taking place in Cleveland and...
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In July 2017, the American Society of Clinical Oncology (ASCO) conducted the National Cancer Opinion Survey to find out what people in the US know about cancer. ASCO released the results in October. The findings have already influenced recommendations made by the organization. Beliefs About Cancer Risk Among other questions, the survey asked 4,016...
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In It’s All In Your Gut, A High Fiber Diet and the Immune System, we introduced the microbiome that lives in our body. It helps with our digestion and makes the short-chained fatty acids (SCFAs) that are important to our immune system. Now several recent studies are looking at bacteria in the bodies of people with cancer. Specifically, these...
Read MoreIn a nutshell This phase 3 trial aims to compare an investigational drug to standard chemotherapy in breast cancer patients with brain metastases. The main outcome to be investigated is overall survival (time from treatment until death from any cause). Another outcome to be measured is progression free survival (time from treatment until disease...
Read MoreIn a nutshell This phase 3 trial aims to evaluate the effectiveness of mindfulness meditation or survivorship education in improving behavioral symptoms in younger stage 0-III breast cancer survivors. The main outcome to be investigated is the change in depressive symptoms. This trial is taking place in the states of California, Maryland and...
Read MoreIn a nutshell This phase 3 trial aims to evaluate how well aspirin can work to prevent recurrence of breast cancer. The main outcome to be investigated is invasive disease free survival. Other outcomes include overall survival (time from treatment until death from any cause) and the incidence of heart disease. This trial is taking place in 985...
Read MoreIn a nutshell This phase 3 trial aims to evaluate how effective pembrolizumab (Keytruda) is at treating triple negative breast cancer. The main outcome to be investigated is the invasive disease free survival. Other outcomes include the overall survival (time from treatment until death from any cause) and side effects. This trial is taking place...
Read MoreIn a nutshell This phase 3 trial aims to evaluate the effectiveness of palbociclib (Ibrance) in combination with standard treatments for HER2 positive breast cancer. The main outcome to be investigated is progression free survival. This trial is taking place in Alabama, Illinois, Iowa, Nebraska and Oklahoma in the United States. The details...
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In a nutshell This study aimed to compare abemaciclib (Verzenio) to a placebo treatment (substance with no active effect). The study concluded that it increased progression-free survival and was relatively safe to use as a first-line treatment. Some background There are several treatment options for hormone positive, HER-2 negative...
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November 2, 2017 Beth Caldwell died. *** “Since being diagnosed with terminal cancer, I have had one goal: to live long enough to see The Girl start kindergarten. She was 2 and a half when I got diagnosed back in March of 2014, and starting kindergarten in 2017 would fall past median survival for me. Thinking about her having to start school without...
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In a nutshell This study examined the effect that restarting hormone treatment, as compared to stopping it, had on progression-free survival. It found that restarting treatment led to increased progression-free survival. Some background Breast cancer is classified into different subtypes depending on the prescence or absence of certain...
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