In a nutshell
This study investigated the effectiveness of OnabotulinumtoxinA (OTA; Botox) in the treatment of stiffness in stroke survivors. Researchers suggested that OTA might be a safe and effective treatment option for these patients.
Some background
Stroke is a serious condition that affects 795,000 people every year in the US. It happens when the blood flow to the brain is cut-off, which can happen due to a blood clot. These cells stop receiving oxygen and begin to die. The abilities controlled by the brain cells are lost causing symptoms such as impaired movement and spasticity (muscle stiffness). Spasticity reduces daily activities, reducing the quality of life of stroke survivors.
Prior clinical trials showed the effectiveness of OTA in the treatment of arm spasticity. However, studies about the use of OTA in real-world settings are limited.
Methods & findings
This study included information about 484 patients with arm spasticity. All patients were treated with OTA. Of these, 74% were stroke survivors. The effectiveness of treatment and satisfaction of doctors and patients were evaluated.
The most common reasons for OTA use were fixed elbow, wrist flexion, internally rotated shoulder, and thumb in the palm. Compared to the first session, there was a significantly improved function and pain with OTA treatment.
Doctors (92.9%) and patients (85.7%) reported being very satisfied with the treatment. 98.6% of the doctors and 92.2% of the patients reported that they would continue with the OTA treatment.
179 patients (37%) reported side effects. The most commonly reported side effect was muscle weakness.
The bottom line
This study concluded that doctors and stroke survivors were very satisfied with OTA treatment for arm spasticity.
Published By :
PM & R: the journal of injury, function, and rehabilitation
Date :
Jan 17, 2020
