Posted by on Oct 19, 2014 in Prostate cancer | 0 comments

In a nutshell

The authors evaluated whether robot-assisted surgery, in patients with high-risk prostate cancer, compares well to other surgical technique.

Some background

One treatment option for patients with high-risk prostate cancer is surgical removal of the prostate (radical prostatectomy). Three different surgical techniques can be used for this. The oldest technique is open surgery (retropubic radical prostatectomy; removal of the prostate gland through a large incision in the abdomen). Then laparoscopic surgery was introduced (minimally-invasive technique involving very small incisions). Most recently robot-assisted surgery was developed (a minimally-invasive technique using robotic assistance to remove the prostate). Understanding possible differences in these techniques is important for achieving the best patient outcome.

Methods & findings

In this study the authors examined whether there is a link between surgical technique and patient survival. They also examined whether there is a link between surgical technique and the risk of the cancer returning. Overall 330 patients were included in the study. 110 patients received robot-assisted surgery, 110 received open surgery and 110 received laparoscopic surgery.

There was no significant difference in the estimated 3-year survival between any of the techniques. There was a 95.4% survival rate for patients who received robot-assisted surgery, 98.1% for patients who received laparoscopic surgery and 100% for patients who received open surgery. There was no significant difference in the estimated number of patients who remained cancer free, when robot-assisted surgery (41.4%) was compared to open surgery (54.1%). Patients who received laparoscopic surgery had a higher estimated chance of remaining cancer free (77.9%). However, the authors were reluctant to conclude anything from this result due to the short follow-up time.

The bottom line

The authors concluded that patients who received robot-assisted surgery had similar outcomes to patients who received laparoscopic and open surgery.

The fine print

The follow-up time was short for patients who received robot-assisted surgery. Further research is needed to confirm these results. 

Published By :

World Journal of Urology

Date :

Mar 09, 2014

Original Title :

Matched comparison of outcomes following open and minimally invasive radical prostatectomy for high-risk patients.

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