In a nutshell
The authors evaluated whether robot-assisted surgery, in patients with high-risk prostate cancer, compares well to other surgical technique.
Some background
One treatment option for patients with high-risk prostate cancer is surgical removal of the prostate (radical prostatectomy). Three different surgical techniques can be used for this. The oldest technique is open surgery (retropubic radical prostatectomy; removal of the prostate gland through a large incision in the abdomen). Then laparoscopic surgery was introduced (minimally-invasive technique involving very small incisions). Most recently robot-assisted surgery was developed (a minimally-invasive technique using robotic assistance to remove the prostate). Understanding possible differences in these techniques is important for achieving the best patient outcome.
Methods & findings
In this study the authors examined whether there is a link between surgical technique and patient survival. They also examined whether there is a link between surgical technique and the risk of the cancer returning. Overall 330 patients were included in the study. 110 patients received robot-assisted surgery, 110 received open surgery and 110 received laparoscopic surgery.
There was no significant difference in the estimated 3-year survival between any of the techniques. There was a 95.4% survival rate for patients who received robot-assisted surgery, 98.1% for patients who received laparoscopic surgery and 100% for patients who received open surgery. There was no significant difference in the estimated number of patients who remained cancer free, when robot-assisted surgery (41.4%) was compared to open surgery (54.1%). Patients who received laparoscopic surgery had a higher estimated chance of remaining cancer free (77.9%). However, the authors were reluctant to conclude anything from this result due to the short follow-up time.
The bottom line
The authors concluded that patients who received robot-assisted surgery had similar outcomes to patients who received laparoscopic and open surgery.
The fine print
The follow-up time was short for patients who received robot-assisted surgery. Further research is needed to confirm these results.
Published By :
World Journal of Urology
Date :
Mar 09, 2014