In a nutshell This article investigated the safety and effectiveness of Lutetium-177 PSMA (LuPSMA) for the treatment of metastatic castration-resistant prostate cancer (mCRPC). The authors concluded that LuPSMA is a safe and effective treatment option for these patients. Some background mCRPC is cancer which has spread from its original site...
Read MoreCurrent PSA level-Between 4 to 10 Posts on Medivizor
Looking for patients with recurrent prostate cancer to test nivolumab
In a nutshell This phase 2 trial will investigate the safety and effectiveness of nivolumab (Opdivo) in recurrent prostate cancer (PC). The main outcome will be disease control. This trial is recruiting at two locations in Boston, MA, US. The details Prostate cancer (PC) is a highly treatable cancer in men. Patients are usually...
Read MorePartial gland ablation versus prostate surgery in men with low- or intermediate-risk prostate cancer
In a nutshell The authors aimed to determine patient outcomes following partial gland ablation compared to robot-assisted radical prostate surgery in men with low- and intermediate- risk prostate cancer. The authors concluded that men with cancer confined to the prostate benefited from partial gland ablation, as it was more successful with fewer side...
Read MoreLooking for patients to compare high and low dose brachytherapy
In a nutshell The aim of this trial was to determine the difference in quality of life on urination when treated with low dose rate (LDR) and high dose rate (HDR) brachytherapy. This study is being conducted in Kelowna, British Columbia, Canada. The details Brachytherapy is a form of radiation therapy that places radioactive material either within...
Read MoreThe effect of anxiety and uncertainty on men under prostate cancer active surveillance
In a nutshell The authors aimed to determine how anxiety and uncertainty affects men with prostate cancer who are undergoing active surveillance. The authors concluded that uncertainty and urinary complications promote anxiety in men on active surveillance for prostate cancer. They also recommend patient education and management of urinary...
Read MoreCan ultrasounds be useful during active surveillance for prostate cancer?
In a nutshell The aim of this study was to see if ultrasounds could be used as a tool to monitor low-risk prostate cancer patients in active surveillance. It was concluded that ultrasounds can be used to monitor changes in prostate cancer, and could extend the time between biopsies. Some background Low-risk prostate cancer is cancer that has not...
Read MoreThe role of active surveillance for men with intermediate-risk prostate cancer
In a nutshell This study examined the role of active surveillance in the management of intermediate-risk prostate cancer. Researchers concluded that active surveillance is a safe management method for selected patients with favorable intermediate-risk disease. Men with more aggressive cancer cells may benefit from active treatment early on. Some...
Read MoreCan biopsies guided by multiple imaging techniques better detect disease progression?
In a nutshell This study examined the benefit of biopsies guided by multiple imaging techniques (scans that provide images of the interior of the body) in men managed with active surveillance. Researchers reported improved detection rates of disease progression when biopsies were guided by multiple imaging techniques. Some background Many men with...
Read MoreSearching for men with low- to intermediate-risk prostate cancer to test precise radiation therapy guided by an imaging technique
In a nutshell This trial aims to examine stereotactic radiosurgery guided by an imaging technique in treating low- to intermediate-risk prostate cancer. The main outcome to be investigated is treatment-related side effects and treatment response. The trial is recruiting in Ohio (USA). The details Stereotactic radiosurgery (SRS) uses a specially...
Read MoreRisk factors, unfavorable disease and the implications for active surveillance in early-stage prostate cancer
In a nutshell The authors aimed to determine the risks of unfavorable disease and predictors of adverse outcomes in men with Gleason score 3 + 4 prostate cancer and how this would affect active surveillance. The authors concluded that active surveillance is a potential treatment option in men with Gleason score 3+4, low PSA scores and low-stage...
Read MoreComparing surgery and radiation therapies for high-risk prostate cancer
In a nutshell This study compared prostate surgery and radiation therapy in treating high-risk prostate cancer. Authors reported similar survival benefits with both treatments. However, high doses of total radiation combined with hormone therapy was associated with the lowest risk of disease progression. Some background Prostate surgery and...
Read MoreExamining the benefits of combining hormone therapy and radiation therapy
In a nutshell This study examined the evidence for combining androgen deprivation therapy (ADT) with radiation therapy for the treatment of high-risk localized prostate cancer. Authors concluded that the combined therapy approach was associated with a survival advantage for intermediate- and high-risk patients. Some background ADT is a type...
Read More
