In a nutshell
This study investigated the effectiveness of brain stimulation for patients with Parkinson's disease and depression. Researchers suggested that brain stimulation improves depression without having an effect on Parkinson's symptoms.
Some background
Parkinson's disease (PD) is the second most common brain disease. This disorder attacks healthy brain cells. These cells lose their abilities causing symptoms such as tremors or muscle weakness. About 35% of patients with PD suffer from depression. This affects their daily life living and quality of life.
Repetitive transcranial magnetic stimulation (rTMS) is a form of brain stimulation used to treat depression and anxiety. The therapy involves using a magnet to activate further certain areas of the brain. Prior studies showed that rTMS improves the outcomes of patients with PD and depression. However, it is still not clear if it also helps in treating PD symptoms.
Methods & findings
This study reviewed 7 other studies that included information about 92 patients with PD and depression. Patients in these studies were treated with either rTMS, fake rTMS (placebo treatment), or antidepressants.
When compared to placebo treatment, rTMS was associated with improved depression. RTMS showed similar improvements in depressive symptoms as antidepressants. However, no significant change was seen in PD symptoms in the rTMS, placebo, and antidepressant groups.
The bottom line
This study concluded that rTMS might be a good option to treat depression in patients with PD.
The fine print
This study was based on medical records. Some information might have been incomplete. This might affect the results.
What’s next?
Discuss with your doctor if you have concerns about depressive symptoms.
Published By :
The International journal of neuroscience
Date :
Oct 02, 2019
