In a nutshell
In this study, researchers examined whether the appearance of lung cancer tumors on PET/CT scans are linked to survival.
Some background
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. Unfortunately, the outcome of NSCLC patients is usually poor. Some specific tumor traits may be useful in predicting patient survival. In theory, common imaging techniques such as positron emission tomography (PET) and computed tomography (CT) can provide important information regarding these traits. For example, in some cancers, a coarsely textured appearance of the tumor is linked to poor survival. This research aimed to determine whether tumor traits on imaging scans are linked to survival in NSCLC patients.
Methods & findings
Researchers examined a total of 122 NSCLC patients, using a combination of PET and CT scans. Tumor images were used to identify features that might be related to survival; including texture and uptake of the contrast dye (increased uptake is a feature of active tumors since the dye is attached to a glucose molecule).
Homogenous (less coarse appearing) tumors were found to be strongly linked to patient survival. Lower uptake of the contrast dye used in PET scans was also related to better survival.
The bottom line
This study concluded that several features of NSCLC as seen on PET/CT scans can predict patient survival.
The fine print
Although this study was small, it was designed to demonstrate that further, larger, studies investigating the prognostic significance of imaging scans in NSCLC may be of benefit.
What’s next?
Consult with your doctor regarding the prognostic significance of your latest PET/CT imaging scan.
Published By :
Clinical Cancer Research
Date :
Jul 05, 2013
