In a nutshell This article investigated the safety and effectiveness of thermal ablation (TA) compared to stereotactic radiation therapy (SRT) for the treatment of non-small-cell lung cancer (NSCLC). The authors concluded that both thermal ablation and stereotactic radiation are safe and can improve survival of these patients. Some...
Read MoreType of lung cancer-Non-small cell lung carcinoma (NSCLC) Posts on Medivizor
Nivolumab compared to docetaxel in lung cancer that has been treated
In a nutshell This study wanted to find out if treating lung cancer with nivolumab (Opdivo) is better than treating it with docetaxel (Taxotere), specifically for lung cancer than has already been treated before. The study found that nivolumab worked better and was safer than docetaxel in treating lung cancer. Some background Nivolumab and docetaxel...
Read MoreBrigatinib versus Crizotinib in ALK-Positive Non-Small-Cell Lung Cancer.
In a nutshell This study wanted to find out if the medication brigatinib (Alunbrig) is better than crizotinib (Xalkori) in treating patients with lung cancer. The study found that survival was significantly longer in patients who were treated with brigatinib compared to those treated with crizotinib. Some background Brigatinib and crizotinib are a...
Read MoreAlectinib vs crizotinib in treating brain or spinal cord tumors in patients with non-small cell lung cancer
In a nutshell This study wanted to find out which medication is better for treating lung cancer that has spread to the brain or spinal cord, crizotinib (Xalkori) or alectinib (Alecensa). The study found that alectinib worked better than crizotinib for treatment of tumors of the brain and spinal cord. Some background Alectinib and crizotinib are two...
Read MoreCisplatin versus lipoplatin in patients with NSC lung cancer and SCCHN
In a nutshell This study wanted to find out which type of medication is better for patients with lung cancer and cancer of the head and neck, cisplatin (Platinol) or lipoplatin (Nanoplatin). The study found that lipoplatin was better overall, and had less side effects than cisplatin. Some background Cisplatin has been used as a type of chemotherapy...
Read MoreAdding local therapy to EGFR inhibitor treatment for lung cancer that has spread to the liver
In a nutshell This study wanted to find out if adding extra treatment targeted to the liver alongside treatment with EGFR inhibitors helped in patients with lung cancer that had spread to the liver. The study found that adding the extra treatment meant the patients survived longer compared to treatment with EGFR inhibitors alone. Some background...
Read MoreOrder of treatments in lung cancer which has spread to the brain
In a nutshell This study wanted to find out what works better in patients with lung cancer that has spread to the brain; performing radiotherapy and treatment with EGFR inhibitors one after the other, or performing radiotherapy and treatment with EGFR inhibitors at the same time. The study found that performing them at the same time had the best results....
Read MoreTreatment for EGFR mutated lung cancer which has spread to the brain
In a nutshell This study wanted to analyse which type of medication is best in treating lung cancer that may have spread to the brain. The study found that using erlotinib (Tarceva) is better than using gefitinib (Iressa) in preventing and treating tumors in the brain that have spread from the lung. Some background Epidermal growth factor receptor...
Read MoreWhich chemotherapy drugs are better after surgery for patients with NSCLC?
In a nutshell This study evaluated the effectiveness of fluorouracil (Adrucil) chemotherapy after surgery in patients with non-small-cell lung cancer (NSCLC). The authors concluded that treatment with fluorouracil resulted in prolonged recurrence-free survival compared to standard chemotherapy regimens. Some background Adjuvant therapy is given in...
Read MoreThe link between time to disease progression and survival after progression in patients with advanced lung cancer
In a nutshell This study looked at a link between time to disease progression and longer survival after progression in patients with advanced BRAF V600E non-small-cell lung cancer. The authors concluded that a longer time to disease progression after treatment was linked to longer survival in these patients. Some background Some non-small-cell...
Read MoreUsing radiation as a secondary treatment to prevent cancer progression
In a nutshell This trial treated patients with advanced non-small-cell lung cancer with consolidative radiation therapy after chemotherapy. The authors concluded that this treatment plan has potential to improve progression free survival and overall survival in these patients. Some background Initial treatment with...
Read MoreThe effect of pembrolizumab on patient health and quality of life
In a nutshell This study examined the effect of pembrolizumab (Keytruda) on the health and quality of life of patients with non-small-cell lung cancer. The study concluded that treatment with pembrolizumab was better for patient health than treatment with chemotherapy. Some background Many tumor cells have a protein called PD-L1 which stops the immune...
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