In a nutshell
This review outlined recent findings on the overall effects of testosterone replacment therapy.
The authors concluded that erectile dysfunction due to testosterone deficiency can be safely and effectively treated with testosterone replacement therapy.
Some background
Testosterone, a male sex hormone, plays an important role in erectile and sexual function. Insufficient production of testosterone can, in some cases, cause erectile dysfunction, which is often treated with testosterone replacement therapy. However, evidence is mixed regarding the effect testosterone therapy has on quality of life and overall health. The aim of this study is to provide an overview of recent findings on testosterone therapy.
Methods & findings
A large review of 17 randomized trials reported a significant benefit of testosterone therapy on erectile and sexual function. Frequency of successful intercourse and ejaculation, number of erections as well as morning erections, sexual satisfaction and sexual drive were all enhanced in men following testosterone therapy. One of the studies reviewed noted significant improvements in libido (sexual drive), but not in sexual satisfaction. However, the effectiveness of testosterone therapy on erectile function is limited to men with low testosterone; testosterone therapy does generally not improve erectile function in men with normal testosterone levels.
Contrary to a number of early findings, there is increasing evidence to suggest that testosterone therapy does not increase the risk of prostate cancer or benign prostatic hyperplasia (prostate enlargement). Some studies have even reported a benefit in prostate health among men receiving testosterone therapy. Prolonged use of testosterone was associated with improvements in insulin resistance (protective against diabetes), bone mineral density (bone strength), muscle mass, and depression symptoms. However, findings regarding the effect of testosterone therapy on the risk of cardiovascular disease (disease of the heart or blood vessels) is inconclusive.
The bottom line
The authors concluded that testosterone therapy is a safe and effective treatment for erectile dysfunction in men with low testosterone.
Published By :
Current opinion in urology
Date :
Jan 13, 2016
An interesting article. I was prescribed Testogel some 5 years ago. and was diagnosed with Prostrate Cancer some 4 years ago. It now seems a connection was assumed by my G.P. The Prostrate cancer was dealt with by radiotherapy and is clear. He now refuses to prescribe Testogel because he perceives there is a risk. My P.S.A. is 0.4. I have all the pre-Testogel symptoms and life is pretty miserable. What’s the solution?
With a history of prostate cancer and the apparent need for Testosterone you need to see a Urologist. Your situation is out of the realm of a GP. I’m not a doctor but I would think there is a balance of how much Testosterone to get you over the hump of your blah feelings without reaching the upper level you were probably getting before you were cut off to eliminate some risk. (Which may not even be a proven risk actually). What is the point of living if you feel like crap