In a nutshell
This study looked at the safety and effectiveness of conservatively managing patients with Peyronie’s Disease (PD). The study found that men with conservatively managed PD had worse outcomes after several years of follow-up.
Some background
Peyronie’s disease is an abnormal curve in the penis. This may be caused by a build-up of scar tissue in the penis. It can reduce sexual function and overall quality of life in men with PD. PD is usually treated with surgical options or injections to the penis to reduce the scar tissue. Conservative management involves observation or oral treatments It is important to research if conservative (non-surgical and non-injectable) management is effective in PD.
Methods & findings
125 men who underwent conservative treatment participated in a survey after an average of 8.4 years following the first onset of PD symptoms.
38% of men felt an overall improvement with conservative management. 26% felt that their condition had worsened since onset. Penile curvature improved in 43%, 37% stayed the same and got worse in 20%. 12% of men developed a second curve. 42% of men reported penile pain. This improved in 64% and worsened in 18%.
Penile shortening was reported in 65% of men. 60% of men reported a reduction in erectile function and more than 40% reported difficulty with penetrative intercourse. 68% of men reported a reduction in sexual frequency and 59% had decreased relationship satisfaction. Around 50% of participants noted loss of self-esteem and confidence.
The bottom line
The study concluded that conservative management was not effective in the majority of men with Peyronie’s disease.
The fine print
This study had a small sample size. Larger studies are required to better understand conservative management.
Published By :
Urology
Date :
Nov 21, 2017
