Can shockwave treatment improve erectile function?

This study evaluated the use of low-intensity shockwave treatment (LIST) for erectile dysfunction.

Researchers concluded that LIST is effective at improving erectile function, even in severe cases.

The development of phosphodiesterase-5 inhibitors (PDE5i), such as Viagra, have revolutionized the treatment of erectile dysfunction. However, not all men respond to PDE5i, and additional treatments are often needed.

Low-intensity shockwave treatment (LIST) is a new therapeutic approach now becoming available. LIST uses low-frequency (non-harmful) shock-waves, which are theorized to increase penile blood flow and stimulate the formation of new blood vessels. LIST is delivered during multiple short sessions. The use of LIST does not require any sedation or anesthetics (drugs to reduce sensation or pain).

The trial included 58 men with erectile dysfunction who previously stopped using PDE5i due to no effect. Two-thirds (37 men) were randomized to receive treatment with LIST. A third (18 men) received a sham procedure (acted as a control group). Erectile function was evaluated at the beginning of the study, and one month following treatment. All men received PDE5i during evaluation of erectile function.

54.1% of men receiving LIST therapy achieved an erection hard enough for vaginal penetration. In comparison, none of the men in the control group showed improved erectile function. According to patient reported scores, treatment was effective in 40.5% of the men receiving LIST, and in none (0%) of the men receiving sham treatment.

16 men from the sham treatment group received LIST therapy one month after the sham treatment. 56.3% of these men achieved an erection hard enough for vaginal penetration.

Researchers concluded that LIST is effective for treating erectile dysfunction, even in severe cases who so not respond to conventional PDE5i treatment.

The results of this small exploratory study should be confirmed in larger studies with longer follow-up.