This trial aims to evaluate the effectiveness of fat-derived stem-cells on chronic wounds. The main outcome being investigated is the change in wound size with treatment.
The details
With diabetes, uncontrolled blood sugar levels can cause nerve and blood vessel damage, which often lead to infections or repeated injuries. Chronic wounds are a serious, and difficult to treat, complication among diabetics.
Recently, stem cells taken from a patient’s own body fat has been investigated as a new treatment for chronic wounds. Stem cells have the potential to grow and develop into any cell type or tissue in the body, including the cells needed for wound healing. This trial will investigate the effects of fat-derived stem cells on chronic wound healing.
Who are they looking for?
This trial will recruit 25 men and women aged 18 and over, who have been diagnosed with a diabetic (or other) chronic wound that does not respond to standard care. Patients with more than 1 chronic wound are eligible. Patients must have enough fat to access fat-derived stem cells.
Patient cannot take part in this trial if they have an uncontrolled infection, a deep infection involving the bone, gangrene (necrosis or death of tissue), cancer or a psychiatric disorder. Women who are pregnant or breast-feeding, patients on dialysis (treatment for kidney failure), or patients taking drugs that could affect wound healing, cannot take part in this trial.
How will it work
Patients will receive a single treatment with stem cells derived from their own body fat. Treatment involves several injections into and surrounding the wound. Wound size will be measured at the beginning of the trial and 12 weeks later.
