In a nutshell This study wanted to find out if the drug pembrolizumab (Keytruda) is effective in treating mucosal melanoma. The study found that pembrolizumab had some effect on mucosal melanoma, and the overall survival of patients was 11 months. Some background Mucosal melanoma is a very aggressive type of cancer, with no specific treatment. Recent...Read More
Clinical Trial Posts on Medivizor
In a nutshell This study analysed a new medication to treat advanced melanoma called SD-101. The study found that patients responded very well to injection of the medication directly into the tumor alongside a common medication called pembrolizumab (Keytruda), although this worked best in patients who had never been treated with pembrolizumab...Read More
In a nutshell This study aimed to find out if the breast cancer treatment palbociclib (Ibrance) works better alone, or in combination with other endocrine therapies (drugs which act on hormone receptors) used to treat estrogen receptor positive (ER+ – a hormone receptor found on the tumor) breast cancer. The authors found that treating women...Read More
What are the outcomes for advanced HL patients receiving intensified BEACOPP chemotherapy after ABVD chemotherapy?
In a nutshell This study investigated the outcomes of advanced-stage classical Hodgkin’s lymphoma (HL) patients treated with ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine) chemotherapy followed by escalated (higher dose) BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone) chemotherapy...Read More
In a nutshell This study compared the safety and effectiveness of R-CHOP (rituximab combined with cyclophosphamide, doxorubicin, vincristine, prednisone) to CHOP-RIT (CHOP followed by iodine-133-tositumomab, Bexxar) as a first-line treatment for follicular lymphoma (FL) patients. This study concluded that immunochemotherapy should remain the standard...Read More
In a nutshell This study investigated the safety and effectiveness of different drugs used to treat gestational diabetes. They found that metformin (Glucophage) is associated with fewer pregnancy complications than glyburide (Glynase), however it is less effective at managing blood sugar levels. Some background Gestational diabetes...Read More
Does dapagliflozin reduce the risk of cardiovascular complications in patients with type 2 diabetes?
In a nutshell This study investigated if dapagliflozin reduces the risk of developing cardiovascular complications in patients with type 2 diabetes. They found that dapagliflozin was associated with a lower risk of non-fatal heart attack and stroke compared to dipeptidyl peptidase-4 inhibitors (DPP-4i). Some background Cardiovascular (CV, heart...Read More
In a nutshell This study investigated if combining bariatric surgery with medical therapy was more effective in treating type 2 diabetes in obese patients. The authors concluded that bariatric surgery in combination with medical therapy was more effective in improving diabetes symptoms in these patients. Some background Bariatric surgery is a...Read More
In a nutshell This study investigated the effect of continuous glucose monitoring (CGM) in managing blood sugar levels in patients with type 1 diabetes treated with multiple daily insulin injections. They found CGM resulted in a clinically meaningful improvement in glycemic (blood sugar) control. Some background Glycemic control is critical for...Read More
Did you know that May 20th is International Clinical Trials Day. It commemorates the first “clinical trial” by James Lind, a Scottish surgeon in 1747. In trying to figure out what caused scurvy, a disease characterized by loss of teeth, bleeding gums and hemorrhaging, he conducted experiments. Twelve men with scurvy were divided into...Read More
In two previous posts, What Do You Think About Clinical Trials? and What Do You Think? Medivizor’s Clinical Trials Perception Survey Results, we learned your perceptions of clinical trials. As a follow-up, we have a short, very useful explainer video produced by the European Patients’ Academy (EUPATI) describing some of the key features of...Read More
In June, we published a post called What Do You Think About Clinical Trials? The post included the results of several surveys about perceptions of clinical trials including the results of a study conducted by MaPS/Millward Brown Analytic and Memorial Sloan Kettering (MSKCC). Medivizor’s Clinical Trials Perception Survey Results In our post...Read More