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Home»Erectile dysfunction» Searching for men with symptoms of an overactive bladder and/or erectile dysfunction to test a new drug treatment (mirabegron).
Clinical Trial
Searching for men with symptoms of an overactive bladder and/or erectile dysfunction to test a new drug treatment (mirabegron).
The aim of the trial is to examine the effect of mirabegron (Myrbetriq) treatment on symptoms of overactive bladder and erectile dysfunction (ED – difficulty achieving and maintaining an erection). The main outcome to be measured is a change in erectile function over time. This trial is being conducted in Baltimore, Maryland.
The details
Erectile dysfunction is a common problem that can affect men of all ages. Drugs called PDEis such as sildenafil (Viagra) are often used to treat ED. However, some men may not respond to this treatment or have side effects. Mirabegron is a drug that may work on receptors in the bladder and penis to help with OAB symptoms and ED. It is necessary to test the safety and effectiveness of this drug.
The main outcome to be measured is a change in erectile function over time. Improvement in bladder function will also be measured.
Who are they looking for?
20 participants will be included in this trial. Participants should have mild or moderate ED, OAB symptoms for at least 3 months, and an urgent need to empty the bladder at least 3 times per day.
Participants should not have a history of unwanted, painful erections, chronic kidney disease, uncontrolled high blood pressure, or liver impairment.
How will it work
All participants will recieve mirabegron once daily for 12 weeks. Questionnaires will be used to measure the outcomes every 2 weeks for 12 weeks.