In a nutshell This review assessed the risk of hypoglycemia (dangerously low blood glucose) with the addition of sodium-glucose co-transporter 2 (SGLT-2) inhibitors to sulfonylureas in patients with type 2 diabetes (T2D). The authors concluded that this combination was associated with an increased risk of hypoglycemia. Some background...
Read MoreType of diabetes-Type 2 Posts on Medivizor
Improved changes in the eye in patients with type 2 diabetes using dapagliflozin compared to glibenclamide.
In a nutshell This study investigated the change in central retinal thickness (CRT) by optical coherence tomography (OCT) in patients with type 2 diabetes (T2D) after 12 weeks of treatment with dapagliflozin (Farxiga) or glibenclamide (Diabeta). The authors concluded that CRT may improve with short-term use of dapagliflozin compared with...
Read MoreDo insulin analogues differ in effectiveness and safety for the treatment of diabetes?
In a nutshell This study assessed the effectiveness and safety of different long-acting and short-acting insulins for the treatment of patients with diabetes. The data supported the use of long-acting insulins instead of neutral protamine Hagedorn (NPH) insulin (Humulin N; Novolin N), as basal insulin for patients with type 2 diabetes (T2D). Some...
Read MoreIs closed-loop glucose control an effective treatment for patients with type 2 diabetes with serious kidney disease?
In a nutshell This study looked at the use of closed-loop glucose control treatment for patients with type 2 diabetes (T2D) requiring dialysis. It found that compared to standard insulin therapy, closed-loop glucose control led to improved glucose control in these patients. Some background Closed-loop glucose control is a form of insulin...
Read MoreCan a vegan diet improve diabetes?
In a nutshell This review looked at whether a vegan diet can improve type 2 diabetes (T2D). It found that a vegan diet can lower glucose (sugar) levels for people with T2D. Some background Vegan diets have become more popular, for both health and ethical reasons. A vegan diet includes plant-based foods and avoids meat, eggs, or dairy. But can a vegan...
Read MoreDo SGLT2 inhibitors increase the risk of urogenital infections in patients with diabetes?
In a nutshell This study looked at the risk of urogenital infections in patients with diabetes taking sodium-glucose co-transporter 2 (SGLT2) inhibitors. It found that SGLT2 inhibitors increase the risk of urogenital infections in women over 50 years of age, especially in the first month of treatment. Some background SGLT 2 inhibitors such...
Read MoreIs tirzepatide as effective as semaglutide for the treatment of type 2 diabetes?
In a nutshell This study looked at tirzepatide, a new treatment for type 2 diabetes, compared to semaglutide (Ozempic). It found that, depending on the dose, tirzepatide was similarly or more effective at controlling blood glucose than semaglutide. Some background Tirzepatide is a new type of medication designed to treat type 2...
Read MoreIs tirzepatide a safe and effective treatment for type 2 diabetes?
In a nutshell This study looked at the safety and effectiveness of tirzepatide (LY-3298176) in patients with type 2 diabetes (T2D) inadequately controlled by diet and exercise alone. It found that compared to placebo, tirzepatide improved diabetes control and weight in these patients. Some background In T2D, there is a resistance of the...
Read MoreCan SGLT2 inhibitors prevent liver disease for people with diabetes?
In a nutshell This review looked at whether sodium-glucose cotransporter 2 (SGLT2) inhibitors can improve non-alcoholic fatty liver disease (NAFLD) for people with type 2 diabetes (T2D). It found that these medications can improve liver function in these patients. Some background NAFLD is a condition in which fat builds up in the liver. This makes the...
Read MoreCan exercise improve nerve health of the heart in patients with diabetes?
In a nutshell This review looked at whether exercise can improve heart rate variability (HRV) for patients with type 2 diabetes (T2D). It found that exercise improved HRV, which indicates better nerve health of the heart. Some background Over time, high blood glucose (sugar) from diabetes can cause nerve damage or neuropathy. People with diabetes...
Read MoreDoes lipoprotein A level affect kidney disease in patients with type 2 diabetes?
In a nutshell This review looked at levels of lipoprotein A (LpA), in people with type 2 diabetes (T2D). It found that people with higher levels LpA in their blood were more likely to have kidney disease. Some background For people living with T2D, an important consideration is managing long-term health and preventing complications. T2D involves...
Read MoreThe effect of adding henagliflozin treatment to metformin in patients with type 2 diabetes.
In a nutshell This study examined the effectiveness of adding henagliflozin (SHR3824) to metformin (Glucophage) in patients with uncontrolled type 2 diabetes (T2D). The authors concluded that the addition of 5 mg or 10 mg of henagliflozin to metformin was well-tolerated and effective in these patients. Some background...
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