In a nutshell This study compared the risk of hypoglycemia (dangerously low blood glucose levels) for insulin glargine 300 U/ml (Gla-300; Toujeo) and standard-of-care basal insulin (SOC-BI) at patients with type 2 diabetes (T2D) with risk factors for hypoglycemia. It found that Gla-300 was associated with a lower risk of hypoglycemia than...
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In a nutshell This study looked at the risk of heart attack, stroke, and death in patients with type 2 diabetes (T2D) and heart disease treated with empagliflozin (Jardiance). They found that empagliflozin reduced the total risk of heart attack, stroke, or death in these patients. Some background Patients with T2D and coronary artery...
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In a nutshell This study looked at the use of omarigliptin (Marizev) in insulin-treated patients with uncontrolled type 2 diabetes (T2D). It found that omarigliptin was well-tolerated and improved blood glucose control. Some background Type 2 diabetes (T2D) is usually treated initially with diet, exercise, and...
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In a nutshell This review focused on the effects of curcumin on blood glucose and lipid (blood fat) levels in patients with uncomplicated type 2 diabetes (T2D). This analysis showed that curcumin has benefits for glucose metabolism and lipid functions in these patients. Some background T2D is a chronic disease closely related to overweight...
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In a nutshell This study examined the effects of intensive therapy on the occurrence of bone fractures in patients with type 2 diabetes (T2D). The data showed that there was no increased risk of fractures with an intensive multifactorial intervention in these patients. Some background Patients with T2D are at increased risk of...
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In a nutshell This review looked at the effect of bariatric surgery (BS; weight loss surgery) on blood vessel damage for people with type 2 diabetes (T2D) and obesity. It found that people who had BS had fewer complications such as kidney disease or nerve damage. Some background T2D is a condition where the body cannot effectively control the...
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In a nutshell This study compared a combination of pioglitazone (Actos) and exenatide (Byetta) to insulin therapy for poorly controlled type 2 diabetes (T2D). It found that more patients receiving pioglitazone and exenatide achieved blood glucose control compared to those receiving insulin. Some...
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In a nutshell This study compared weekly semaglutide (Ozempic) and daily sitagliptin (Januvia) for type 2 diabetes (T2D) in an Asian population. It showed that patients treated with semaglutide had a greater improvement in T2D control and increased weight loss compared to those treated with sitagliptin. Some...
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In a nutshell This study looked at the effect of treatment with polyethylene glycol loxenatide (PEX168) alone in patients with poorly controlled type 2 diabetes (T2D). They found that PEX168 significantly improved blood glucose control in these patients. Some background Blood glucose is controlled by many hormones. The most...
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In a nutshell This study looked at the safety and benefits of starting sotagliflozin (Zynquista) in patients with type 2 diabetes (T2D) who were recently hospitalized for heart failure. They found that patients started on sotagliflozin within 2 days of discharge from the hospital had a lower risk of serious complications including...
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In a nutshell This study used real-world data to compare SGLT-2 inhibitors versus other medications for patients with type 2 diabetes (T2D). It found that SGLT-2 inhibitors led to lower kidney disease and better overall outcomes. Some background T2D is a condition in which the body cannot effectively lower the amount of glucose (sugar) in the blood....
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In a nutshell This review looked at how SGTL2 inhibitors with or without metformin (Glucophage) affect heart and kidney health for patients with type 2 diabetes (T2D). It found that these medications improve cardiovascular and kidney outcomes, whether or not patients are also taking metformin. Some background SGLT2 inhibitors are a group of T2D...
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