In a nutshell This study investigated the psychological impact of Roux-en-Y gastric bypass with silastic ring (SR-RYGB) or sleeve gastrectomy (SG) in patients with type 2 diabetes (T2D) and obesity and associations with improved symptoms of depression and quality of life (QoL). The study showed that both types of bariatric (weight-loss) surgery were...
Read MoreType of diabetes-Type 2 Posts on Medivizor
Can new glucose-lowering medications influence stroke risk in patients with type 2 diabetes?
In a nutshell This review assessed the effects of new glucose-lowering drugs on stroke risk in patients with type 2 diabetes (T2D). The study showed that glucagon-like peptide-1 receptor (GLP-1) agonists are potentially beneficial for stroke risk in patients with T2D. Some background Patients with diabetes are at a higher risk of developing...
Read MoreHow safe and effective is orally delivered insulin for patients with early-stage type 2 diabetes?
In a nutshell This study compared the safety and effectiveness of different doses of an oral insulin capsule formulation (Capsulin™) to patients with early-stage type 2 diabetes (T2D). The data showed that twice-daily, orally administered Capsulin at a dose of 150 international units (IU) was safe and resulted in a significant lowering...
Read MoreDoes metformin use in pregnancy lead to childhood weight gain?
In a nutshell This study looked at the use of metformin (Glucophage) for the management of type 2 diabetes (T2D) in pregnancy. The study showed that compared to infants exposed to placebo, those exposed to metformin during pregnancy did not show any signs of increased weight or body mass index (BMI; a measurement of weight in relation to...
Read MoreHow can counselling affect pancreatic beta-cell function in patients with type 2 diabetes?
In a nutshell This study analyzed the long-term effect of behavioral counseling on increasing daily physical activity (PA) and reducing sedentary (SED) time on changes in beta-cell (β-cell) function and glucose control in patients with type 2 diabetes (T2D). The authors concluded that increasing moderate-to-vigorous-intensity physical activity...
Read MoreDo some anti-diabetic medications affect the risk of fractures in patients with type 2 diabetes?
In a nutshell This analysis investigated the relationship between anti-diabetic medications and the risk of fractures in patients with type 2 diabetes (T2D). The data showed that glucagon-like peptide-1 receptor agonists (GLP1-RAs) and sulfonylurea (SU) provided better protection against fractures compared to thiazolidinedione (TZD) or dipeptidyl...
Read MoreEvaluating the effects of the plant-based polyphenol-rich extract TOTUM-63 on glucose control in patients with prediabetes or early-stage type 2 diabetes.
In a nutshell This study evaluated the effects of the plant-based polyphenol-rich extract TOTUM-63 on glucose control in patients with prediabetes or early-stage newly diagnosed type 2 diabetes (T2D). The data showed that TOTUM-63 was safe and lowered fasting blood glucose in these patients. Some background Patients with...
Read MoreIs dorzagliatin an effective add-on treatment to metformin in patients with type 2 diabetes?
In a nutshell This study assessed the effectiveness and safety of adding dorzagliatin (HMS552) to metformin therapy in patients with type 2 diabetes (T2D) with inadequately controlled blood glucose (sugar) while using metformin (Glucophage) alone. The data showed effective blood glucose control, good tolerance, and safety in patients...
Read MoreHow safe and effective is dorzagliatin treatment in patients with type 2 diabetes?
In a nutshell This study evaluated the effectiveness and long-term safety of dorzagliatin in patients with type 2 diabetes (T2D) without previous antidiabetic treatment. The authors concluded that dorzagliatin blood glucose (sugar) levels with no serious side effects in these patients. Some background Glucokinase is a...
Read MoreCan teneligliptin be safely and effectively given to patients with inadequately controlled type 2 diabetes by triple oral antidiabetic drug treatment?
In a nutshell This study compared the effectiveness and safety of teneligliptin (Tenelia) to placebo in patients with type 2 diabetes (T2D) that was inadequately controlled with triple oral antidiabetic drugs (OADs). The study showed that teneligliptin may be considered as a fourth add-on OAD treatment in these patients. Some background T2D is...
Read MoreCan physical activity affect glucose levels variations in patients with diabetes?
In a nutshell This study evaluated the effect of physical activity interventions on glycemic variability (GV; glucose levels variations) in patients with diabetes. The data showed that physical activity was associated with significantly reduced GV in these patients. Some background Physical activity has been shown to reduce hemoglobin A1c (the...
Read MoreHow beneficial is sodium-glucose co-transporter 2 inhibitor treatment for patients with type 2 diabetes mellitus and heart failure?
In a nutshell This study reviewed the long-term use of sodium-glucose co-transporter 2 inhibitors (SGLT-2i) on the risk of mortality and hospitalization for heart failure (HHF) in patients with type 2 diabetes (T2D) and heart failure (HF). The authors concluded that long-term use of SGLT-2 inhibitors can help to reduce mortality risk and HHF in...
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