In a nutshell This study reviewed the effectiveness and safety of safinamide (Xadago) treatment in patients with Parkinson’s disease (PD). Researchers suggested that safinamide improves the outcomes of patients also taking levodopa. Some background PD is a chronic disease that affects more than 10 million people worldwide. It...
Read MoreTaking medications-On medications Posts on Medivizor
Does levodopa inhalation powder improve wearing-off time of patients with Parkinson’s disease?
In a nutshell This study investigated the effectiveness and safety of levodopa inhalation powder (CVT-301; Inbrija) in the treatment of wearing-OFF symptoms in patients with Parkinson's disease (PD). Researchers suggested that CVT-301 decreased the daily OFF time of these patients with manageable side effects. Some background...
Read MoreEvaluating the effects of DA-9701 on gastrointestinal symptoms in patients with Parkinson’s disease
In a nutshell The study evaluated the effectiveness of DA-9701 (Motilitone) on gastrointestinal symptom-related quality of life (GIS-QoL) in patients with Parkinson’s disease (PD) who are on stable dopaminergic medications. The main finding was that DA-9701 improved GIS-QoL in such patients. Some background Gastrointestinal symptoms (GIS)...
Read MoreContinuous treatment with levodopa/carbidopa improves wearing off periods in patients with Parkinson’s disease
In a nutshell This study compared the effectiveness of continuous (non-stop) levodopa/carbidopa (LC) treatment in patients with Parkinson's disease (PD). Researchers suggested that this treatment is associated with improved outcomes for these patients. Some background Parkinson's disease (PD) affects 7 to 10 million people worldwide. It causes...
Read MoreHow is levodopa affecting the sleep of patients with Parkinson’s disease?
In a nutshell This study investigated if there is an association between treatment with levodopa and sleep in patients with Parkinson’s disease (PD). Researchers suggested that there is a strong association between sleep abnormalities and patients treated with levodopa. Some background PD is a chronic disease that affects brain...
Read MoreApomorphine infusion improves quality of life of patients with Parkinson’s disease
In a nutshell This study investigated the effectiveness of continuous subcutaneous apomorphine infusion (CSAI) in the treatment of Parkinson’s disease (PD) symptoms. Researchers suggested that CSAI improves movement symptoms and quality of life of these patients. Some background Parkinson’s disease is a chronic disorder that affects...
Read MoreEvaluating a new treatment for gastric symptoms in patients with Parkinson’s disease
In a nutshell This study determined the effect of DA-9701 (Motilitone) on gastric motility (GM: movements of the digestive system) in patients with Parkinson’s disease. Researchers suggested that this drug improves GM in these patients. Some background Patients with Parkinson’s disease (PD) have an abnormal digestive function. This can...
Read MoreEvaluating rasagiline as add-on therapy in patients with Parkinson’s disease
In a nutshell This study evaluated the safety and effectiveness of rasagiline (Azilect) in patients with Parkinson’s disease (PD) and wearing-off effects (motor symptoms worsen as levodopa wears off before the next dose is taken). This study concluded that rasagiline improved symptoms and quality of life in these patients. Some background PD is...
Read MoreSurgery/deep brain stimulation and medical therapy improves the quality of life of patients with Parkinson’s disease
In a nutshell This study investigated whether surgery and medical therapy increase the quality of life of patients with advanced Parkinson´s disease (PD). Researchers suggested that surgery combined with medical therapy was associated with improved quality of life for these patients, when compared to therapy alone. Some background PD is...
Read MoreLooking for advanced PD patients to test Exablate ultrasound, a new, one-time, non-surgical procedure for motor symptoms
In a nutshell The Exablate Neuro study evaluates the safety and effectiveness of focused ultrasound procedures for treating motor symptoms in patients with Parkinson’s disease (PD) who are no longer having success with medications. The details The Exablate Neuro uses focused ultrasound beams to ablate (destroy) a small area on one side of the...
Read More