In a nutshell This study investigated if fresh (FR) or frozen (FZ) embryo transfer (ET) results in higher live birth rates (LBR) in women with undergoing in vitro fertilization (IVF). They found that LBR was higher after FZET in women with high progesterone levels. Some background Many women with fertility problems will undergo assisted...
Read MoreIn a nutshell This trial will investigate if the success of deferred embryo transfer (DET) is affected by pre-implantation genetic screening (PGS). The main outcome measured will be the live birth rate. This trial takes place in California, Oklahoma, and Pennsylvania, the United States. The details Infertility is a condition that...
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In a nutshell This study investigated if there is a link between male body mass index (BMI) and success of assisted reproductive treatment (ART). They found that high BMI in males is linked to reduced pregnancy and live birth rates in couples undergoing ART. Some background The causes of infertility in a couple are not always easily identified....
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In a nutshell This study investigated if mild ovarian stimulation is as effective as conventional stimulation in vitro fertilization (IVF). They found that mild ovarian stimulation provides greater safety and lower cost, in addition to comparable success rates. Some background A part of the IVF process, women undergo a procedure to harvest...
Read MoreIn a nutshell The aim of this phase 4 trial is to assess if a single dose of a gonadotrophin-releasing hormone (GnRH) agonist enhances implantation during in vitro fertilization (IVF). The main outcome to be measured is the rate of live births. This study is being conducted in New Jersey, in the United States. The details In very early pregnancy,...
Read MoreIn a nutshell This phase 4 trial aims to evaluate if co-administration of a gonadotrophin releasing-hormone (GnRH) agonist improves oocycte maturity. The main outcome to be investigated is the number of mature oocytes. The details One of the important steps during in vitro fertilization (IVF) is stimulating the maturation of oocytes (eggs). GnRH...
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In a nutshell This study explored the option of using low-dose human chorionic gonadotropin (hCG) alone to complete follicle maturity in natural cycle in vitro fertilization (IVF). The results showed that hCG alone could be used to complete follicle maturity. There was no requirement for follicle stimulating hormone (FSH). Some background...
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In a nutshell This study examined whether bemfola has a similar safety and effectiveness profile as Gonal-f in women undergoing assisted reproductive technology. Some background Follicle-stimulating hormone (FSH) is a female hormone which is involved in the development of eggs in the ovaries. Gonal-f (follitropin alfa) is a drug which acts in...
Read MoreIn a nutshell This study examined the rate of ectopic pregnancy after in vitro ferilization differed with the use of fresh or frozen-thawed eggs. Some background In-vitro fertilization (IVF) is when a male sperm fertilizes the females’ egg in a laboratory dish outside the body, and is implanted into the...
Read MoreIn a nutshell This trial will examine whether introducing human chorionic gonadotropin into the uterus prior to implantation increases the success rate of in vitro fertilization. The effectiveness of this treatment will be measured through the implantation, pregnancy, and ongoing pregnancy rates. This trial is being conducted in Atlanta,...
Read MoreIn a nutshell This article reviewed currently published data concerning the efficacy and safety of the different sperm retrieval techniques for men with reduced sperm production. Some background Around 10% of infertile men suffer from non-obstructive azoospermia, which describes a condition in which very few sperm cells are produced in the...
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In a nutshell This study examined whether progesterone levels affect pregnancy rates during in vitro fertilization. Some background Hormone levels are vitally important to the proper functioning of the female reproductive cycle. Estrogen (a female hormone) rises as the time of ovulation (release of an egg from the ovary) nears. This surge in...
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