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Searching for patients with lymphoma or leukemia to test T-cell therapy after stem cell transplantation

Posted by on May 24, 2019 in Leukemia | 0 comments

In a nutshell This phase 2 trial is evaluating how well CD8+ memory T-cell therapy works in patients with leukemia or lymphoma after a stem cell transplant (SCT). The main outcome to be measured will be the number of patients who have full chimerism (donor cells work completely and only donor cells can be identified after transplant) after therapy. This...

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Searching for patients with lymphoma or leukemia to test T-cell therapy after stem cell transplantation

Posted by on May 24, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This phase 2 trial is evaluating how well CD8+ memory T-cell therapy works in patients with leukemia or lymphoma after a stem cell transplant (SCT). The main outcome to be measured will be the number of patients who have full chimerism (donor cells work completely and only donor cells can be identified after transplant) after therapy. This...

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Looking for patients with estrogen receptor-positive breast cancer to test a new treatment combination

Posted by on May 11, 2019 in Breast cancer | 0 comments

In a nutshell This phase 2 trial will evaluate the safety and effectiveness of ribociclib (Kisqali) combined with hormonal therapy in patients with estrogen receptor-positive (ER+) breast cancer (BC). The main outcome will be the number of patients that complete 1 year of treatment and survival without signs of cancer. The trial will...

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Searching for patients with early-stage HER2+ breast cancer to trial a new treatment regime

Posted by on Apr 24, 2019 in Breast cancer | 0 comments

In a nutshell This study will examine how safe and effective the medication atezolizumab (Tecentriq) is in combination with other anti-cancer medicines for treating early stage HER2+ breast cancer. The main outcome that will be measured is how many patients completely respond to treatment, with no trace of the cancer remaining. The details...

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Searching for patients with relapsed or unresponsive follicular lymphoma to trial a new drug

Posted by on Apr 24, 2019 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This trial will evaluate the effects of a new treatment parsaclisib (INCB050465) in relapsed or unresponsive follicular lymphoma (FL). Response rate, survival, and side effects will be the main outcomes measured. The details Many patients are cured with treatments for follicular lymphoma (FL). Some, however, lose response to therapy...

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Searching for patients with HIV-positive lymphoma to test EPOCH-R chemotherapy

Posted by on Apr 22, 2019 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This study is evaluating the effectiveness of EPOCH-R chemotherapy for patients with non-Hodgkin's lymphoma (NHL) who are HIV-positive. The main outcome to be measured will be survival without cancer growing or spreading. This study is recruiting in Bethesda, Maryland, United States. The details Patients with NHL who are...

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Looking for patients with relapse/unresponsive lymphoma to test a treatment combination

Posted by on Mar 29, 2019 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This study is evaluating the best dose and side effects of mogamulizumab (Poteligeo) plus pembrolizumab (Keytruda) for relapsed or unresponsive lymphoma. The main outcomes to be measured will be the best dose and side effects of treatment, as well as survival without the tumor growing. This study is being conducted in Sacramento,...

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Looking for children and young adults with Hodgkin lymphoma to test a new treatment.

Posted by on Mar 28, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This trial is examining the safety and effectiveness of pembrolizumab (Keytruda) in the treatment of children and young adults with classical Hodgkin lymphoma (HL). The main outcome to be measured will be a response to treatment. This trial is recruiting in the Republic of Korea and the United States. The details...

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Searching for patients with low-risk breast cancer to participate in a study involving radiotherapy

Posted by on Mar 25, 2019 in Breast cancer | 0 comments

In a nutshell This trial aims to find out if targeted radiotherapy on the breast in women with low-risk breast cancer after breast-conserving surgery will prevent the cancer from coming back. The main outcome that will be measured is how long it takes before the breast cancer comes back. The study is being conducted in Canada and the United States. The...

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Looking for elderly patients with chronic lymphocytic leukemia to test a treatment combination

Posted by on Mar 16, 2019 in Leukemia | 0 comments

In a nutshell This trial is examining the effectiveness of ibrutinib and obinutuzumab with or without venetoclax in the treatment of older patients with chronic lymphocytic leukemia (CLL). The main outcome to be measured will be survival without cancer worsening. This trial is recruiting in the United States. The details Patients with CLL are often...

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