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Seeking patients with relapsed follicular lymphoma for dosing study of idelalisib

Seeking patients with relapsed follicular lymphoma for dosing study of idelalisib

Posted by on Sep 20, 2020 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This study will evaluate the best dose of idelalisib (Zydelig) for patients with relapsed follicular lymphoma (FL). The primary outcomes are overall response and side effects.  The details FL is a slow-growing cancer of B-cells, a type of white blood cell. Idelalisib is a medication that inhibits certain proteins involved in...

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Searching for patients with advanced triple-negative breast cancer to trial a treatment combination

Searching for patients with advanced triple-negative breast cancer to trial a treatment combination

Posted by on Sep 6, 2020 in Breast cancer | 0 comments

In a nutshell This trial is aiming to examine the effectiveness of ipatasertib in combination with atezolizumab (Tecentriq) and paclitaxel (Taxol) for the treatment of advanced triple-negative breast cancer (TNBC) that cannot be surgically removed. The main outcomes to be measured in this trial is survival without progression of the disease and...

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Searching for patients with rheumatoid arthritis to switch to a rituximab biosimilar

Searching for patients with rheumatoid arthritis to switch to a rituximab biosimilar

Posted by on Sep 6, 2020 in Rheumatoid Arthritis | 0 comments

In a nutshell This phase 3 trial will investigate the safety and effectiveness of switching from rituximab (Rituxan/Mabthera) to DRL_RI in patients with rheumatoid arthritis (RA). The main outcome will be the rate of side effects and anti-drug drug antibodies (ADAs). This study is recruiting at several locations in the United...

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Searching for patients with relapsed or unresponsive small lymphocytic lymphoma to test an immune cell-stimulating treatment

Posted by on Dec 19, 2019 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This study is looking for patients with relapsed or unresponsive chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) to test IOV-2001, a treatment that boosts cancer-killing immune cells.  The main outcome that will be measured is how well patients respond to treatment. This study is recruiting in Columbus, OH, the...

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Searching for patients with relapsed or unresponsive chronic lymphocytic leukemia to test an immune cell-stimulating treatment

Posted by on Dec 19, 2019 in Leukemia | 0 comments

In a nutshell This study is looking for patients with relapsed or unresponsive chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) to test IOV-2001, a treatment that boosts cancer-killing immune cells.  The main outcome that will be measured is how well patients respond to treatment. This study is recruiting in Columbus, OH,...

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Looking for patients with advanced triple negative breast cancer to test an experimental drug with three functions

Posted by on Oct 31, 2019 in Breast cancer | 0 comments

In a nutshell This trial is examining the safety and effectiveness of experimental drug mRNA-2752 in patients with advanced triple-negative breast cancer. The main outcome of the trial will be the number of side effects experienced by patients and response to treatment. This trial is recruiting in the United States and Israel. The details...

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Searching for patients with early breast cancer to trial a partial-radiation treatment

Posted by on Oct 24, 2019 in Breast cancer | 0 comments

In a nutshell This trial aims to find out what dose of radiation therapy is effective in the shortest time period for women with newly diagnosed breast cancer, or ductal carcinoma in-situ (DCIS). The main outcome that will be measured is if patients experience any side effects. The study is taking place in New Jersey and New York, the United States. The...

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Looking for patients with hormone-receptor positive metastatic breast cancer to test an experimental biological drug

Posted by on Sep 30, 2019 in Breast cancer | 0 comments

In a nutshell This study is examining the effectiveness of biological drug sacituzumab govitecan (IMMU-132) compared to standard treatments for patients with hormone receptor-positive metastatic breast cancer. The main outcomes that will be measured are cancer responsiveness to the drug and survival of patients without the cancer growing. This trial...

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Searching for patients with leukemia or lymphoma to test modified stem cell transplants donated by relatives

Posted by on Sep 20, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This trial is examining the effectiveness of modified stem cell transplants (SCT) donated by patient relatives, which have certain immune cells removed to prevent transplant rejection in patients with leukemia and lymphoma. The main outcome will be the maximum dose of SCT that can be given safely and is effective. This study is...

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Looking for patients with advanced triple negative breast cancer to test a new treatment

Posted by on Sep 10, 2019 in Breast cancer | 0 comments

In a nutshell This phase 1/2 trial is examining the effectiveness of treatment with GB1275 alone or in combination with immunotherapy in patients with solid tumors such as triple-negative breast cancer. The main outcome to be measured will be dose toxicity and tumor response to the treatment. This study is being conducted in Tennessee and Texas, US. The...

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Looking for patients with non-Hodgkin lymphoma to test new treatment using patient’s own immune cells

Posted by on Aug 22, 2019 in Non-Hodgkin lymphoma | 0 comments

In a nutshell This trial is examining the effectiveness of CTX110, a treatment that modifies a patient’s own immune cells to treat relapsed or unresponsive non-Hodgkin lymphoma (NHL). The main outcome of this study is to see the number of patients that respond to treatment and side effects experienced. This study is recruiting in...

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