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Currently pregnant or breastfeeding-Neither Posts on Medivizor

Does Tamoxifen reduce the risk of cancer in a second breast in BRCA1 and BRCA2 carriers?

Posted by on Feb 24, 2013 in Breast cancer | 0 comments

In a nutshell The risk of breast cancer is high (~80%) in women who inherit a damaged (mutated) gene called BRCA1 or BRCA 2 (‘BRCA carriers’). Following the first diagnosis, their risk of developing another tumor in the second breast within 10 years is 30%. Some background Some types of breast cancer need estrogen (female sex...

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Chemotherapy Treatments For Triple-Negative Breast Cancer

Posted by on Feb 24, 2013 in Breast cancer | 0 comments

This paper reviews chemotherapy options for triple-negative breast cancers. Breast cancer cells express 3 main receptors that can be targeted with therapy: Estrogen receptors (ER), Progesterone receptors (PR) and HER2. Triple-negative breast cancers (TNBCs) do not express these 3 receptors and make up approximately 15% of breast cancers. Such tumors do...

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Preserving Fertility during Cancer Treatment

Posted by on Feb 24, 2013 in Breast cancer | 0 comments

In a nutshell This paper reviews available options for having children after cancer treatment. The main conclusion is that sperm, egg and embryo preservation techniques can help young women have children after breast cancer treatment.  Alternative options, such as ovarian tissue preservation, are also being developed. Some background...

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Standard Chemotherapy versus Capecitabine (Xeloda) in Older Women with Early-Stage Breast Cancer

Posted by on Feb 24, 2013 in Breast cancer | 0 comments

In a nutshell This trial compared standard chemotherapy regimens and Capecitabine (Xeloda) in women over 65 years old. The main outcome was that standard chemotherapy worked better in this age group. Some background Capecitabine is generally used in breast cancer resistant to other chemotherapy. It is also the first approved treatment that can be...

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Detecting cancer cells in the blood stream as means to predict recurrence

Posted by on Feb 24, 2013 in Breast cancer | 0 comments

In a nutshell The present study evaluated whether the presence of cancer cells in the blood stream predicts a worse prognosis in women with operable breast cancer. The main finding was that progression-free survival (time before cancer progression) and overall survival were lower if circulating cancer cells were detected in the blood. Some background...

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What is the preferred duration of chemotherapy? – A review of clinical trials

Posted by on Feb 24, 2013 in Breast cancer | 0 comments

The aim of this paper was to identify if a longer course of chemotherapy was better than a short course. The authors look at how long patients survived with metastatic breast cancer or with no further cancer progression. Breast cancer is called metastatic when it has spread from the breast to other parts of the body such as the lymph nodes, lungs,...

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