In a nutshell The study compared outcomes of apalutamide (A; Erleada), darolutamide (D; Nubeqa), and enzalutamide (E; Xtandi) in treating nonmetastatic castration-resistant prostate cancer (nmCRPC). The authors found that A and E had better metastasis-free survival (MFS) compared to D. Some background Men with CRPC fail to respond to...
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In a nutshell This study looked at the long-term risk of secondary cancers following brachytherapy (BT; internal radiation therapy) for prostate cancer. It found that treating prostate cancer with BT had a low risk of secondary cancers. Some background Prostate cancer is a slow-growing cancer of the prostate gland. Men with prostate cancer that has...
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In a nutshell The study assessed whether enzalutamide (Xtandi) plus androgen deprivation therapy (ADT) increased overall survival (OS) of patients with nonmetastatic, castration-resistant prostate cancer (CRPC). The study found improved survival in patients with CRPC treated with enzalutamide. Some background ADT is a type of hormonal therapy...
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In a nutshell The study looked at the sequence of dose-escalated radiotherapy (RT) and androgen-deprivation therapy (ADT) in the treatment of local prostate cancer (LPCa). The study found that treatment with ADT before RT had the same outcome as treatment with ADT and RT at the same time. Some background LPCa is a form of cancer that is...
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In a nutshell This study compared local cryosurgery (CRYO) against androgen deprivation therapy (ADT) for the treatment of locally recurring prostate cancer (LRPC). The study found local cryosurgery had a longer overall survival (OS) when compared to ADT. Some background LRPC is cancer that has re-occurred in the prostate gland...
Read MoreIn a nutshell This study aimed to evaluate the use of high-intensity focal ultrasound (HIFU) for the treatment of localized prostate cancer. This study found that HIFU is a safe treatment with good oncological results and minimal side-effects. Some background High-intensity focused ultrasound (HIFU) is a non-invasive technique that uses...
Read MoreIn a nutshell This phase 3 trial will compare the safety and effectiveness of hypofractionated radiotherapy (HF-RT) to standard radiotherapy (RT). The main outcomes will be the number of grade 2 side effects and disease control. This trial is recruiting in Houston, Texas, United States. The details Radiation therapy (RT) is a...
Read MoreIn a nutshell This study aimed to investigate long-term outcomes of radiation therapy after prostate surgery for prostate cancer. This study found that this is a safe treatment option for these patients. Some background Prostate surgery is a common treatment for prostate cancer (PCa). Intensity-modulated radiation therapy (IMRT) is another option....
Read MoreIn a nutshell This study aimed to investigate a surgical procedure used to treat prostate cancer, retzius sparing laparoscopic robotic-assisted radical prostatectomy (RS-RALP). This study found that RS-RALP had similar side-effects and outcomes to other robotic surgeries. Some background Prostate surgery is a treatment option for prostate cancer...
Read MoreIn a nutshell This study aimed to evaluate the use of irreversible electroporation (IRE) in the treatment of prostate cancer. This study found that IRE had low side-effect rates and promising outcomes. Some background Irreversible electroporation (IRE) uses high-energy pulses of electricity to destroy cancer cells. The brand name for...
Read MoreIn a nutshell This study investigated the rate of bladder cancer (BC) and rectal cancer (RC) after localized prostate cancer (PC) treatment. They found that brachytherapy (BT) increased the risk of BC and RC in these patients. Some background Prostate cancer (PC) is a common cancer in men. There are many treatment options for PC. Some involve...
Read MoreIn a nutshell This study aimed to investigate the outcomes of intermediate risk-risk prostate cancer after different treatments. This study concluded that prostate surgery might have a higher survival than radiotherapy. Some background There a several options to treat intermediate-risk prostate cancer (IR-PC). Radical prostatectomy (RP; surgery to...
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