In a nutshell This study aimed to evaluate two different timelines of delivering radiotherapy, 56 Gy delivered in 16 treatments or 67 Gy delivered in 25 treatments, to the prostate. This study found that both treatments are safe and effective in the treatment of prostate cancer. Some background Hypo-fractionated radiation therapy...
Read MoreCurrent stage -Stage II Posts on Medivizor
Imaging and biopsy in men undergoing active surveillance
In a nutshell The authors aimed to determine whether multiparametric magnetic resonance imaging (mpMRI)/ultrasound fusion biopsy improves Gleason grade detection compared to systematic biopsy in active surveillance. The authors concluded that due to the low sensitivity of mpMRI for detecting cancer grade 7 or higher, systematic biopsy will still need...
Read MoreLooking for patients to compare high and low dose brachytherapy
In a nutshell The aim of this trial was to determine the difference in quality of life on urination when treated with low dose rate (LDR) and high dose rate (HDR) brachytherapy. This study is being conducted in Kelowna, British Columbia, Canada. The details Brachytherapy is a form of radiation therapy that places radioactive material either within...
Read MoreSearching for men with intermediate- or high-risk prostate cancer to test a short course of very focused radiation therapy
In a nutshell This phase 2 trial aims to compare conventional radiation therapy with a very focused type of radiation therapy for intermediate- and high-risk prostate cancer. The main outcome to be investigated is the number of side effects and the rate of disease recurrence at 5 years. The trial is recruiting in British Columbia, Canada. The details...
Read MoreSurvival benefits for men treated with local therapies before starting chemotherapy
In a nutshell This study examined the benefits of administering local therapies before chemotherapy for prostate cancer. Researchers reported lower mortality risks for men treated with local therapies before chemotherapy. Some background Local therapies, such as surgery or radiation, are first-line treatments for localized (confined) prostate...
Read MoreThe effect of combined radiation and hormone therapy on long-term fatigue
In a nutshell This study examined the effect of combined radiation and hormone therapy on long-term fatigue. Researchers reported severe fatigue during and up to 4 years after treatment. Men with increased cancer markers and symptoms were more likely to report higher fatigue levels. Some background Radiation therapy and hormone therapy are often...
Read MoreLower PSA levels increase or decrease mortality risk depending on Gleason score
In a nutshell This study evaluated prostate-specific mortality risk based on PSA (prostate specific antigen) levels in men with high-grade disease. Authors reported increased mortality risk with lower PSA levels in men with high-grade disease. A decreased mortality risk was observed with lower PSA levels in men with low-grade disease. Some background...
Read MoreLow-risk prostate cancer: Predictors of disease progression during active surveillance
In a nutshell This review examined predictors of disease progression in low-risk prostate cancer during active surveillance. Researchers concluded that certain blood markers, biopsy results, and ethnicity could help predict which patients were more likely to experience disease progression. Some background Active surveillance of prostate...
Read MoreLDH as an early predictor of cancer survival
In a nutshell This study investigated the relationship between lactate dehydrogenase (LDH) levels and cancer-specific survival. Researchers concluded that LDH can be used as an early indicator of cancer outcomes. Some background Early cancer detection methods have significantly improved cancer survival rates. There is increasing evidence to...
Read MoreTreating recurrent prostate cancer with lymph node surgery
In a nutshell The authors aimed to determine the long-term outcomes of lymph node surgery in patients who experienced prostate cancer recurrence after prostate surgery. Some background Prostate surgery involves surgically removing the prostate gland in patients with prostate cancer. In some cases, following surgery, some patients may experience...
Read MoreIdentifying prostate cancer progression
In a nutshell The authors aimed to identify the best options available to identify metastatic prostate cancer. Some background Metastatic prostate cancer is cancer that has spread from the prostate gland into tissues and organs around the body. In some cases patients with metastatic cancer can become resistant to certain treatments, such as...
Read MoreThe complications associated with hormone therapy in advanced prostate cancer
In a nutshell The authors aimed to determine the complications of hormone therapy in patients with advanced prostate cancer. Some background Hormone therapy is a prostate cancer treatment that targets the male sex hormones, such as testosterone, active in cancer. In some patients hormone therapy can cause side effects such as bone damage,...
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