In a nutshell This study assessed whether patients with uncontrolled diabetes would benefit from adding ertugliflozin to their treatment regime. The authors concluded that ertugliflozin improved blood sugar control among those unable to do so with the combination of metformin (Glucophage) and sitagliptin (Januvia) alone. Some...
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In a nutshell This study investigated the potential of dapagliflozin (Farxiga) as an add-on treatment to insulin therapy. The authors concluded that dapagliflozin was safe and helped improve glycemic outcomes in those with uncontrolled type 1 diabetes. Some background Insulin is a hormone which helps control blood sugar levels....
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In a nutshell This study compared the effectiveness and safety of two forms of insulin glargine in adults with type 2 diabetes (T2D). It was determined that both forms were effective in controlling blood glucose levels, but that the more concentrated form was slightly less likely to cause hypoglycemia (dangerously low blood glucose). Some background...
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In a nutshell This study investigated if glyburide (Glynase) was safer and more effective than insulin in patients with gestational diabetes. They found that glyburide was associated with an increased risk of neonatal hypoglycemia (low blood sugar) but was well tolerated overall. Some background Gestational diabetes mellitus (GDM)...
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In a nutshell This study examined whether lifestyle interventions could improve control of blood glucose levels (glycemic control) in people with advanced type 2 diabetes (T2D). They determined that certain lifestyle interventions resulted in a significant decrease in HbA1c levels (a measure of glycemic control). Some background T2D is...
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In a nutshell This study investigated the safety and effectiveness of semaglutide on glycemic control in insulin-naïve patients with type 2 diabetes. They found that semaglutide improved glycemic (blood sugar) control and was well-tolerated by patients. Some background Controlling blood glucose levels is essential in type 2 diabetes. The...
Read MoreIn a nutshell This study assessed the safety and effectiveness of a new formulation of exenatide compared to sitaglipitin in patients with sub-optimal blood sugar control taking metformin. This study concluded that exenatide reduced blood sugar levels over 3 months more effectively than sitaglipitin. Some background There are many blood...
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In a nutshell This study investigated the effect of continuous glucose monitoring (CGM) in managing blood sugar levels in patients with type 1 diabetes treated with multiple daily insulin injections. They found CGM resulted in a clinically meaningful improvement in glycemic (blood sugar) control. Some background Glycemic control is critical for...
Read MoreIn a nutshell This study will investigate the ability of 3 different methods to improve self-care in patients with uncontrolled diabetes. These 3 methods are; text-messaging, health coaches, and enhanced usual care. This study will take place in Mississippi and Tennessee. The details Previous research suggests that encouraging text messages from...
Read MoreIn a nutshell This study examined the safety and effectiveness of lixisenatide (Lyxumia) in elderly patients with type 2 diabetes. Researchers reported significant improvements in blood sugar levels and body weight with lixisenatide. Some background Type 2 diabetes is a common condition in elderly people. Lifestyle changes, such as diet and...
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In a nutshell This study compared the effects of two drugs, metformin (Glucophage) and glyburide (DiaBeta), in the treatment of gestational diabetes mellitus (GDM). The study also examined a combination of the two drugs. It found that the effectiveness and safety of the drugs was similar, and that using a combination reduced the need to use...
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In a nutshell This article compared the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) to insulin in patients with type 2 diabetes (T2D). The study concluded that weekly GLP-1 RAs were more effective in controlling blood glucose, and that all GLP-1 RAs reduced weight, compared to insulin. Some background T2D is a progressive...
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