In a nutshell This study is investigating the safety and effectiveness of the EndoBarrier system for patients with poorly controlled type 2 diabetes (T2D) and obesity. The main outcome to be measured will be the change in blood glucose levels. This trial is recruiting in multiple locations across the United States. The details Bariatric surgery is the...
Read MoreIn a nutshell This study wanted to compare how well two different kinds of insulin, insulin glargine (Lantus) 300u/ml, and insulin degludec (Tresiba), worked for people with type 2 diabetes. The study found that the patients in both groups had similar blood glucose control and similar episodes of low blood glucose events. Some...
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In a nutshell This study wanted to find out what factors put young people with type 1 diabetes at risk of developing impaired blood flow or heart issues. The study found that poor control of blood sugars and traditional risk factors for heart disease, such as high blood pressure and obesity, were associated with an increased risk of blood flow issues in...
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In a nutshell This article investigated the safety and effectiveness of triple therapy with low dose dapagliflozin (Farxiga) plus saxagliptin (Onglyza) added to metformin (Glucophage) in uncontrolled type 2 diabetes (T2D). The authors concluded that triple therapy significantly improved blood glucose control in these patients. Some background T2D...
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In a nutshell This article compared the safety and effectiveness of insulin detemir (Levemir) plus liraglutide (Victoza) vs insulin detemir plus insulin aspart (Novolog) in the management of type 2 diabetes (T2D). The authors concluded that detemir plus liraglutide is a safe and more...
Read MoreIn a nutshell This article investigated the safety and effectiveness of liquid and lyophilized (freeze-dried powder) albiglutide (Tanzeum) in the management of type 2 diabetes (T2D). The authors concluded that the two forms of the drug were similarly effective and safe in these patients. Some background In T2D...
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In a nutshell The aim of this study was to evaluate the safety and effectiveness of a fixed combination of lixisenatide (Lyxumia) and insulin glargine (Lantus) for the treatment of type 2 diabetes (T2D) in older patients. The main finding of the study was that a lixisenatide/insulin glargine (iGlarLixi; Soliqua) combination improved blood...
Read MoreIn a nutshell This trial is examining the safety and effectiveness of efpeglenatide versus dulaglutide in patients with poorly controlled type 2 diabetes (T2D) who are on metformin. The main outcome to be measured will be a change in HbA1c (blood test measuring average blood glucose over the past 3 months). This trial is being conducted in the United...
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In a nutshell The aim of this study was to evaluate how safe and effective ertugliflozin (Steglatro) is in patients with type 2 diabetes (T2D) that is not controlled well with metformin (Glucophage). The study found that ertugliflozin is safe and improved blood glucose control, body weight, and blood pressure in these patients. Some background...
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In a nutshell This study investigated the suitability of IDegLira for treating patients with uncontrolled type 2 diabetes. The authors concluded that using IDegLira was safe and effective at reducing blood-sugar levels. Some background IDegLira is an injectable, fixed-ratio combination of basal insulin (degludec) and a glucagon-like peptide-1...
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In a nutshell This study examined the effects of dapagliflozin (Farxiga) and exenatide (Byetta) in different groups of people with type 2 diabetes (T2D). It was determined that a combination of the drugs reduces weight, blood pressure, and triglycerides (type of fat found in the blood) more than either alone. The greatest...
Read MoreIn a nutshell This study investigated the effectiveness and safety of ertugliflozin (Steglatro) plus sitagliptin (Januvia), compared to either drug used alone, in people with type 2 diabetes (T2D). It was determined that the combination was better at controlling blood glucose levels, without increasing the risk of side effects. Some background...
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