In a nutshell This phase 3 trial will investigate the safety and effectiveness of adagloxad simolenin (AGS)/OBI-821 in triple-negative breast cancer (TNBC). The main outcome will be a change in survival without invasive disease. The details Breast cancer (BC) is one of the most common cancers. BC treatment depends on the tumor type....
Read MoreConfined or spread disease-Confined only to the breast Posts on Medivizor
Patient-reported outcomes after breast-conserving treatment: what is the impact of radiotherapy?
In a nutshell This study investigated patient-reported outcomes related to radiotherapy (RT) for breast cancer. They found that patients were dissatisfied with outcomes after RT but this was not a long-term effect. Some background Breast cancer is the most common form of cancer in women. A number of strategies are used to treat BC. A lot of BC cases...
Read MoreSearching for patients with early stage breast cancer to trial a new radiation treatment plan
In a nutshell The trial aims to investigate a new way of delivering radiation therapy in women with early-stage breast cancer. This will involve low doses of radiation therapy being aimed at the part of the breast where the tumor is or was. The main outcomes that will be measured are side effects and recurrence rate. This trial is recruiting in Missouri,...
Read MoreSearching for patients with low-risk breast cancer to participate in a study involving radiotherapy
In a nutshell This trial aims to find out if targeted radiotherapy on the breast in women with low-risk breast cancer after breast-conserving surgery will prevent the cancer from coming back. The main outcome that will be measured is how long it takes before the breast cancer comes back. The study is being conducted in Canada and the United States. The...
Read MoreBreast conserving surgery plus radiotherapy vs mastectomy in stage 1 breast cancer
In a nutshell This study wanted to find out which treatment was better for stage 1 breast cancer, either breast-conserving surgery plus radiotherapy, or mastectomy alone. The study found that breast conserving surgery plus radiotherapy was better than mastectomy for patients with stage 1 breast cancer. Some background There are a number of treatment...
Read More10 years of treatment vs 5 years of treatment with hormone therapy in patients with early stage breast cancer.
In a nutshell This study wanted to find out if continuing hormone therapy for 10 years was more effective than doing it for 5 years in patients with early stage breast cancer. The study found that the patients who continued treatment for 10 years survived for longer without the disease coming back compared to those who were only treated for 5...
Read MoreHomeopathic medicine for hot flushes in patients with breast cancer
In a nutshell This study wanted to determine if a homeopathic treatment for hot flushes would improve the quality of life of patients undergoing hormonal therapy for breast cancer. The study concluded that after four weeks, there was a modest improvement in the quality of life of these patients. Some background Hormonal therapy for breast cancer...
Read MoreEffects of breast reconstruction compared to mastectomy only on survival and risk of recurrence of breast cancer
Layman Title Effects of breast reconstruction compared to mastectomy only on survival and risk of recurrence of breast cancer In a nutshell This study aimed to find out if breast reconstruction using deep inferior epigastric perforator (DIEP) flap reconstruction resulted in higher levels of recurrence compared to mastectomy alone. The authors found that...
Read MoreGenetics used to guide breast cancer chemotherapy treatment
In a nutshell This study examined if the presence of certain genes had an effect on endocrine (hormone) treatment alone compared to chemoendocrine (chemotherapy and hormone) treatment for breast cancer. The study concluded that endocrine and chemoendocrine had the same effectiveness in women with certain genetic factors. Some background Breast cancer...
Read MoreDoes radiotherapy improve outcomes for patients with primary breast diffuse large B-cell lymphoma?
In a nutshell This study evaluated the impact of radiotherapy on the outcomes of rituximab (Rituxan)-treated patients with primary breast diffuse large B-cell lymphoma. This study concluded that radiotherapy has significant therapeutic benefits for these patients. Some background Primary breast diffuse large B-cell lymphoma (DLBCL) is a rare type of...
Read MoreWhich is the better treatment for breast cancer to improve quality of life?
In a nutshell This study aimed to find out if the quality of life after treatment was different in women who had whole breast irradiation (radiation treatment to the whole breast) for early breast cancer compared to women who had accelerated partial breast irradiation (short radiation treatment to part of the breast) with brachytherapy. The...
Read MoreRisk of secondary cancers in patients who have been treated for early stage breast cancer
In a nutshell This study aimed to examine the risk of developing a secondary cancer after breast conserving therapy for early stage breast cancer patients. This study found that patients who have been treated for early stage breast cancer do not have a significantly higher risk of secondary cancers. Some background Women with early stage breast...
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