In a nutshell The Exablate Neuro study evaluates the safety and effectiveness of focused ultrasound procedures for treating motor symptoms in patients with Parkinson’s disease (PD) who are no longer having success with medications. The details The Exablate Neuro uses focused ultrasound beams to ablate (destroy) a small area on one side of the...
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In a nutshell This study investigated the effectiveness of repetitive transcranial magnetic stimulation (rTMS) at controlling the symptoms of Parkinson´s patients. Researchers suggested that rTMS reduced the symptoms of these patients. Some background Parkinson’s is a progressive disease. Medications are the main treatment option,...
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In a nutshell This study investigated whether receiving deep brain stimulation (DBS) or medical therapy affects the quality of life of patients with Parkinson´s disease. Researchers suggested that DBS is associated with neuropsychological changes that affect the quality of life of these patients. Some background Parkinson’s disease is...
Read MoreIn a nutshell This study is examining the safety and effectiveness of the 9zest mobile rehabilitation app for independent older adults with Parkinson’s disease. The main outcomes to be measured are number of falls during exercise and the usability of the app. This study is recruiting in Las Vegas, Nevada. The details The 9zest app delivers...
Read MoreIn a nutshell This study is investigating the metabolism and safety of opicapone in patients with Parkinson’s disease who are already taking levodopa/carbidopa. This study is recruiting in Glendale and Long Beach, California as well as Farmington Hills, Michigan. The details Opicapone is a new COMT inhibitor. This type of treatment prolongs the...
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In a nutshell This study is investigating the impact of onabotulinum toxin A (Botox) injection on rest tremors in patients with Parkinson’s disease. The main outcome to be measured is the change in tremor symptoms before and after treatment. This study is recruiting in Chapel Hill, North Carolina. The details Rest tremors are often...
Read MoreIn a nutshell This study investigated the long-term satisfaction following deep brain stimulation (DBS) in patients with advanced Parkinson’s disease (PD). The study concluded that patients were satisfied with their decision to undergo DBS, however pre-operative expectations were high and were not associated with satisfaction...
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In a nutshell This study investigated the effectiveness of deep brain stimulation (DBS) and/or medical therapy for patients with advanced Parkinson’s disease. This study concluded that DBS plus medical therapy improved Parkinson's symptoms and quality of life compared to medical therapy alone. Some background Levodopa remains the...
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In a nutshell This study looked at the effectiveness of droxidopa (Northera) at improving symptoms of Parkinson’s disease. The study concluded that patients treated with droxidopa in addition to their usual treatment had improved motor function compared to those treated with placebo (substance with no active effect) Some background...
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In a nutshell This study explored the timing of progression of Parkinson’s disease using the Hoehn and Yahr scale. They concluded that the transition time between disease stages a useful way to measure disease progression. Some background The progression of Parkinson’s symptoms varies between people. The Hoehn and Yahr (H&Y) scale is...
Read MoreIn a nutshell This study evaluated the tolerability and safety of ropinirole (Requip XL) versus other dopamine agonists taken alone or together with levodopa to treat Parkinson’s disease (PD). This study concluded that ropinirole was associated with similar side effects to other dopamine agonists. Some background For many years, dopamine...
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In a nutshell This study investigated the use of medication to treat depression in patients diagnosed with Parkinson’s disease (PD). They concluded that treatment with selective serotonin reuptake inhibitors (SSRIs) and cognitive behavioral therapy significantly improved depression in these patients. Some background The main symptoms...
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