In a nutshell This study determined the effect of DA-9701 (Motilitone) on gastric motility (GM: movements of the digestive system) in patients with Parkinson’s disease. Researchers suggested that this drug improves GM in these patients. Some background Patients with Parkinson’s disease (PD) have an abnormal digestive function. This can...
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Evaluating nerve disease in patients with Parkinson’s disease
In a nutshell This study investigated the causes of polyneuropathy (PN; damage of peripheral nerves that causes weakness and numbness) in patients with Parkinson’s disease. Researchers suggested that long-term levodopa treatment might be associated with PN in these patients. Some background Parkinson’s disease (PD) affects brain cells...
Read MoreLee Silverman voice treatment in the treatment of voice symptoms in patients with Parkinson´s disease
In a nutshell This study compared two speech treatments in patients with Parkinson´s disease with voice symptoms. Researchers suggested that Lee Silverman voice treatment (LSVT LOUD) is a more effective method when compared to articulation treatment (LSVT ART) in these patients. Some background Around 89% of patients with Parkinson’s...
Read MoreDepression is associated with freezing of gait in patients with Parkinson´s disease
In a nutshell This study investigated the factors associated with freezing of gait (brief incapacity to walk) of patients with Parkinson´s disease (PD). Researchers suggested that depression is associated with this symptom. Some background PD is a long-term disease that affects brain cells. Symptoms generally come slowly with time and may...
Read MoreRasagiline improves symptoms of Japanese patients with early Parkinson´s disease
In a nutshell This study investigated the effectiveness of rasagiline (Azilect) in the treatment of Japanese patients with early Parkinson´s disease (PD). Researchers suggested that rasagiline improved the treatment outcomes of these patients. Some background PD is the second most common neurodegenerative disease. It affects more than 1% of...
Read MoreA sleep disorder can predict increased severity of Parkinson’s disease
In a nutshell This study evaluated how REM sleep behavior disorder was related to the progression of Parkinson’s disease. Results showed that patients with REM sleep disorder experienced faster progression of certain symptoms of Parkinson’s disease. Some background Parkinson's disease is caused by the breakdown and death of nerves...
Read MoreDonepezil may help prevent thought and behaviour decline for patients with Parkinson’s
In a nutshell This study examined the effect of donepezil for treating Parkinson’s disease. Results showed that donepezil [Aricept?] improved patient’s thought and behavior, but did not prevent the progression of Parkinson’s. Some background Parkinson’s disease is caused by the breakdown and death of nerves within the...
Read MoreCan diet help improve symptoms of Parkinson´s disease?
In a nutshell This study evaluated the safety and effectiveness of a low-fat diet compared to a ketogenic diet (KD; high fat and low carbohydrates) to treat symptoms of Parkinson´s disease. Researchers suggested that both diets were associated with improved symptoms in these patients. Some background Parkinson’s disease (PD) is a...
Read MoreMultidisciplinary rehabilitation improves quality of life of patients with Parkinson’s disease
In a nutshell This study evaluated whether an intensive rehabilitation treatment improves the quality of life of patients with Parkinson disease (PD). Researchers suggested that this treatment could improve the quality of life of these patients in the short and long terms. Some background PD is a progressive disease that affects body movement, balance...
Read MoreMirabegron treatment for overactive bladder symptoms in Parkinson’s disease
In a nutshell This study looked at using Mirabegron (Myrbetriq) to treat overactive bladder (OAB) symptoms in patients with Parkinson's disease (PD). This study concluded that mirabegron is safe and effective for OAB symptoms in patients with PD. Some background PD is a progressive disease caused by loss of brain cells that make a substance...
Read MoreParkinson’s Disease at a cellular level: Recent research
Parkinson’s disease affects around one million people in the US and between seven and ten million worldwide. In people with Parkinson’s disease, the neurons in the brain that produce dopamine die off. Dopamine is a neurotransmitter, a chemical that helps send messages in the brain. It is involved in many functions such as movement, reward, memory,...
Read MoreMagnetic stimulation of the brain for the treatment of depression associated with Parkinson´s disease
In a nutshell This study reviewed the use of repetitive transcranial magnetic stimulation (rTMS) to treat depression in patients with Parkinson´s disease. Researchers suggested that rTMS is associated with positive effects in the treatment of depression in these patients. Some background Parkinson´s disease is caused by the...
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