In a nutshell This review analyzed the efficacy and safety of vandetanib (Caprelsa) in combination with chemotherapy for the treatment of advanced non-small cell lung cancer. Some background Chemotherapy is often the standard of treatment for advanced non-small cell lung cancer (NSCLC). However, response rates to treatments, as well as survival,...
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In a nutshell This study evaluated the role of three markers, measured by positron emission tomography (PET) scans, in predicting survival and recurrence among early stage non-small cell lung cancer (NSCLC) patients. Some background New methods of predicting survival of early stage patients with NSCLC have been the focus of recent investigation....
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In a nutshell This study examined complement activation as a new marker to predict prognosis among lung cancer patients. Some background Lung cancer screening methods, such as blood tests or imaging scans, can be helpful not only in diagnosing lung cancer, but also in predicting prognosis and response to treatment. The search for reliable...
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Many With Lung Cancer Never Smoked There’s a movement afoot–energized by parents, children, brothers, sisters, sons and daughters– to change the language of cancer prevention. Why? Because the number 1 cancer–lung cancer– is the least funded, is often caught late and has a very poor prognosis. And by the way, lots of people...
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In a nutshell In this study, researchers examined whether the appearance of lung cancer tumors on PET/CT scans are linked to survival. Some background Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. Unfortunately, the outcome of NSCLC patients is usually poor. Some specific tumor traits may be useful in predicting...
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In a nutshell This study evaluated the safety and efficacy of chemotherapy (CT) given concurrently with 3-dimensional conformal radiotherapy (3D-CRT) for the treatment of patients with metastatic non-small cell lung cancer or mNSCLC (lung cancer that has spread to distant organs of the body). Some background Chemotherapy (CT) uses drugs that...
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In a nutshell This study investigated the use of a sorafenib (Nexavar) for the treatment of non-small cell lung cancer. Some background Approximately 85% of lung cancers are classified as non-small cell lung cancers (NSCLC). NSCLC spreads easily throughout the lung tissue forming small malignant tumors. Although treatments have advanced in recent...
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Our body consists of trillions of cells that follow a certain cycle of growing, dividing, and dying. When these cells grow out of control, they may become cancerous and invade other tissues. Cancer is a group of over 100 diseases, distinctive by the uncontrolled growth and spread of abnormal cells, and if remain untreated, may even cause death. According to...
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In a nutshell This study investigated whether the SOX2 gene is linked to improved survival in patients with non-small cell lung cancer. Some background Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, but its prognosis remains poor. Individual prognostic factors are important in helping both patients and doctors guide...
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In a nutshell This study compared the efficacy of erlotinib (Tarceva) versus GemCarbo chemotherapy in patients with advanced epidermal growth factor receptor (EGFR) mutation-positive non-small-cell lung cancer (NSCLC). The study also compared the effect of the two treatments on the quality of life (QoL) of the...
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In a nutshell This study examined the effectiveness of onartuzumab (MetMAb) and erlotinib (Tarceva) as treatment for non-small cell lung cancer patients. Some background Non-small cell lung cancer (NSCLC) is the most common form of lung cancer. In many patients, a mutation in the EGFR gene, which is involved in...
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In a nutshell This trial assessed whether chemotherapy based on ERCC1 and RRM1 levels is more beneficial than the conventional carboplatin and gemcitabine (GemCarbo) chemotherapy, in patients with advanced non-small-cell-lung cancer (NSCLC). Some background ERCC1 and RRM1 are proteins found in human cells and are a part of the cell's cycle of...
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