In a nutshell This study reviewed the treatments for elderly patients with early-stage Hodgkin lymphoma. The study concluded that combined chemotherapy and radiation therapy has the best outcomes, however the use of radiation therapy is not ideal. Some background Hodgkin lymphoma (HL) is generally considered a curable disease. However, outcomes in...
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Brentuximab vedotin plus dacarbazine or bendamustine to treat elderly patients with Hodgkin lymphoma
In a nutshell The authors compared the effectiveness of brentuximab vedotin (BV, Adcetris) plus dacarbazine versus BV plus bendamustine (Treanda). The authors concluded that both treatments are effective, but BV plus dacarbazine is recommended because it is safer than BV plus bendamustine. Some background Hodgkin lymphoma (HL) is...
Read MoreWar on Cancer: The Right Metaphor?
“For me, having lost my husband, it’s frustrating to hear publicly people saying to John McCain, ‘If anybody can beat this you can — you’re so tough.’ Not that it’s intentionally hurtful, but it does leave those of us who’ve lost a loved one thinking, ‘Was my loved one not tough enough? Did he not fight hard enough?'” ~Dannagal...
Read MoreUsing TARC blood levels to predict treatment success for patients with Hodgkin lymphoma
In a nutshell This study looked at how well thymus and activation-regulated chemokine (TARC) levels can predict outcomes for patients with Hodgkin lymphoma. The authors concluded that an early reduction in TARC levels can predict that treatment will be successful. Some background Hodgkin lymphoma (HL) is generally considered a curable...
Read MorePediatric vs adult treatment regimens for children, adolescents, and young adults diagnosed with classical HL
In a nutshell This study compared the outcomes for children and young adults diagnosed with classical Hodgkin lymphoma treated with either pediatric or adult regimens. The study concluded that survival outcomes were the same for patients treated with the pediatric or adult regimens. Some background Hodgkin lymphoma (HL) is generally...
Read MoreExperimental CD30 CAR-T therapy for patients with relapsed Hodgkin lymphoma
In a nutshell The authors looked at the side effects and outcomes of the experimental treatment CAR-T biological therapy in the treatment of Hodgkin lymphoma. The authors concluded that CAR-T treatment is safe and can be beneficial for some patients. Some background Many new treatments are being developed to treat patients with relapsed...
Read MoreRadiation therapy in modern Hodgkin lymphoma treatment
In a nutshell This study reviewed the effectiveness of radiation therapy in treating patients with Hodgkin lymphoma. The study concluded that radiation therapy is continuing to evolve, and it can be successfully used to treat early or advanced Hodgkin lymphoma. Some background Hodgkin lymphoma (HL) is generally considered a curable disease....
Read MoreIf Not For Immunotherapy…
“I’m barely 27 and if it were not for immunotherapy and cancer research, I would not have seen 25.” So starts Stefanie Joho speech at a 2017 Congressional Hearing called “Progress in Immunotherapy: Delivering Hope and Clinical Benefit to Cancer Patients.” When Stefanie was 22, she was diagnosed with a very aggressive Stage II...
Read MoreUsing erythropoietin mouthwash to reduce the occurrence of oral mucositis in patients receiving autologous stem cell transplantation
In a nutshell This study looked at how effective erythropoietin mouthwash was at preventing oral mucositis in cancer patients being treated with autologous stem cell transplantation. The study concluded that rinsing with erythropoietin mouthwash can prevent oral mucositis. Some background Oral mucositis (OM) is a complication associated with...
Read MoreThe risk of developing a second cancer in Hodgkin lymphoma survivors
In a nutshell This study looked at the effect of family history on the development of secondary cancers in Hodgkin lymphoma survivors. The authors concluded that HL survivors have a higher risk of developing a secondary cancer than the general population, especially if they have a family history of cancer. Some background Hodgkin lymphoma...
Read MoreAdult vs pediatric regimens for treating adolescents and young adults with Hodgkin lymphoma
In a nutshell This study compared adult and pediatric treatment regimens for adolescent and young adult patients with Hodgkin lymphoma. The study concluded that adolescent and young adult patients treated with the pediatric regimen have better outcomes than those treated with the adult regimen. Some background Hodgkin lymphoma (HL) is one of...
Read MoreThe use of radiation therapy after autologous stem cell transplantation in patients with relapsed or refractory Hodgkin lymphoma
In a nutshell The authors looked at the effect of radiation therapy after autologous stem cell transplantation for patients with relapsed or refractory Hodgkin lymphoma. The authors concluded that radiation therapy after autologous stem cell transplantation improved time to disease progression. Some background Hodgkin lymphoma (HL) is generally...
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