In a nutshell This study determined the effectiveness and safety of brentuximab vedotin (Adcetris) administered with AVD (doxorubicin, vinblastine, dacarbazine) chemotherapy for stage 3 or 4 classical HL (Hodgkin’s lymphoma). The study concluded that brentuximab vedotin with AVD was more effective than ABVD (AVD plus bleomycin). Some...
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In a nutshell This study examined outcomes for patients with Hodgkin lymphoma receiving chemotherapy followed by proton therapy. Researchers reported good disease control and a low rate of side effects at 3 years. However, continued follow-up is needed. Some background The combination of chemotherapy and radiation therapy provides the best...
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In a nutshell This study examined the effect of donor type on allogeneic stem cell transplant outcomes in patients with relapsed Hodgkin lymphoma. This study reported reduced disease progression in patients with partially matched donors compared to identical matches. Some background While Hodgkin lymphoma is a curable disease, some patients...
Read MoreIn a nutshell This study examined the impact of multi-drug resistant organisms in patients who had undergone stem cell treatment. The study concluded that patients colonized with multi-drug resistant organisms should be watched closely for infections after transplantation. Some background Stem cell transplantation is a treatment used in...
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“I think all too often we underestimate the impact of a cancer diagnosis on the mental health and well-being of the individual, thus it goes unaddressed.” ~Stephanie Zimmerman, MSN Receiving a diagnosis of cancer can bring on feelings of worry, fear, dread, anger, uncertainty and loss. Research indicates that, for some people, these symptoms of...
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In a nutshell This phase 2 trial aims to test the effectiveness of a combined treatment with Brentuximab vedotin (Adcetris) in patients 60 years of age or more with Hodgkin lymphoma. The main outcome to be measured will be tumor response to the treatment and side effects. This trial is recruiting throughout the United States. The details...
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In a nutshell This study looked at changing treatment intensity after a PET scan for patients with advanced stage Hodgkin lymphoma. The authors concluded that reducing treatment intensity for patients with a negative PET scan can reduce negative side effects and improve long-term outcomes. Some background Advanced stage Hodgkin lymphoma (HL) can...
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In a nutshell This study looked at changing treatment intensity after a PET scan for patients with advanced stage Hodgkin lymphoma. The authors concluded that reducing treatment intensity for patients with a negative PET scan can reduce negative side effects and improve long-term outcomes. Some background Advanced stage Hodgkin lymphoma (HL) can...
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In a nutshell This study aimed to investigate if a treatment combination including brentuximab vedotin (Adcetris) would be effective in treating patients with advanced Hodgkin’s lymphoma. This study concluded that treatment combinations with and without brentuximab vedotin were effective but one (BrECADD) was associated with fewer side...
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In a nutshell This review examined the risk of secondary cancer with different types of Hodgkin lymphoma treatment. The study concluded that combined modality treatment and more intense chemotherapy increase the risk of developing a secondary cancer, but also reduce the risk of early relapse. Some background Hodgkin lymphoma (HL) is widely...
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In a nutshell This review explored the risk of developing a secondary cancer after being treated for Hodgkin lymphoma with chemotherapy and/or radiotherapy. The review concluded that intensified chemotherapy and radiotherapy are more effective but are associated with a greater risk of developing a secondary cancer. Some background Hodgkin...
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In July 2017, the American Society of Clinical Oncology (ASCO) conducted the National Cancer Opinion Survey to find out what people in the US know about cancer. ASCO released the results in October. The findings have already influenced recommendations made by the organization. Beliefs About Cancer Risk Among other questions, the survey asked 4,016...
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