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Hodgkin’s lymphoma Posts on Medivizor

Predicting ischemic heart disease and stroke in survivors of childhood cancer

Posted by on Mar 10, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study investigated the individual risk of ischemic heart disease and stroke through age 50 in 5-year survivors of childhood cancer. The authors concluded that these conditions can be reasonably predicted using information available after childhood cancer therapy. Some background For the 400,000 childhood cancer survivors in the...

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Right To Try: Needed Legislation or Snake Oil?

Right To Try: Needed Legislation or Snake Oil?

Posted by on Mar 10, 2018 in Blog, Breast cancer, Colorectal cancer, Hodgkin's lymphoma, Leukemia, Lung cancer, Lymphoma, Melanoma, Multiple Myeloma, Non-Hodgkin lymphoma, Prostate cancer | 1 comment

Thirty-eight states in the US have passed “Right To Try” laws. These are laws that are created to give terminally ill patients who have run out of options access to experimental drugs that have not completed the FDA approval process.  There is an effort underway to pass this type of legislation on a federal level. On February 8, the #LCSM (Lung...

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Do two cycles of stem cell therapy lead to longer progression free survival in relapsed or refractory HL patients?

Posted by on Feb 27, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study determined if progression-free survival (time from treatment before disease progression) could be improved in patients with relapsed or refractory Hodgkin’s lymphoma (HL) who received two cycles (tandem) of autologous hematopoietic stem cell transplantation (AHSCT). This study concluded that tandem AHSCT appears effective...

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Reviewing current progress in Hodgkin’s lymphoma research and treatment

Posted by on Feb 27, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell The current paper reviews the development of new therapies for Hodgkin's lymphoma (HL), including combination chemotherapy and immunotherapies. Some background Hodgkin’s lymphoma (HL) comprises 10% of new lymphoma cases in the U.S., with 21% of these occurring in adolescents. Thanks to advancements in treatment, mortality rates...

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Risk of developing breast cancer among female Hodgkin lymphoma patients

Posted by on Feb 27, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study looked at the risk of developing breast cancer while on hormone replacement therapy for female patients who were treated with radiation for Hodgkin lymphoma. The authors concluded that radiation therapy significantly increased the risk of developing breast cancer, and hormone replacement therapy did not significantly increase the...

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Outcomes for Hodgkin lymphoma patients treated with combined modality treatment

Posted by on Feb 27, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study looked at the long term outcomes for patients with Hodgkin lymphoma who were treated with radiation therapy. The study concluded that patients treated with radiation therapy had better outcomes compared to patients not treated with radiation therapy.  Some background Patients with Hodgkin lymphoma (HL) generally have good...

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Does liposomal doxorubicin improve heart side effects in lymphoma patients compared to conventional doxorubicin?

Posted by on Feb 27, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study investigated the impact of liposomal doxorubicin (Adriamycin) on cardiac side effects in lymphoma patients compared to conventional doxorubicin. The study suggested that liposomal doxorubicin can reduce cardiac effects and still be an effective therapy, particularly for patients at high risk for anthracycline-induced...

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Does PET/CT scanning after one ABVD cycle better predict treatment outcomes than scanning after two cycles (iPET2)?

Posted by on Feb 20, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study analyzed PET/CT scans from new Hodgkin’s lymphoma patients after one (iPET1) or two (iPET2) cycles of ABVD chemotherapy. The study concluded that iPET2 is better than iPET1 at predicting ABVD outcomes in HL patients. Some background Interem PET/CT scanning is used to guide early treatment for new Hodgkin’s...

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What are the long-term outcomes for early-stage HL patients who received radiotherapy alone or combined with chemotherapy?

Posted by on Feb 15, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study determined long-term risk of death from all causes using data from 1,541 early-stage (stage 1-2) Hodgkin’s lymphoma (HL) patients who received radiotherapy (RT) alone or RT with chemotherapy. This study concluded that this risk was significantly lower for patients treated in the most recent era of radiation therapy thanks...

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What are the outcomes for advanced HL patients receiving intensified BEACOPP chemotherapy after ABVD chemotherapy?

Posted by on Feb 9, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study investigated the outcomes of advanced-stage classical Hodgkin’s lymphoma (HL) patients treated with ABVD (doxorubicin, bleomycin, vinblastine, dacarbazine) chemotherapy followed by escalated (higher dose) BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone) chemotherapy...

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What are the real-world outcomes for ASCT-ineligible patients with refractory or relapsed HL who are given brentuximab vedotin?

Posted by on Feb 5, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study determined the real-world outcomes for patients with relapsed or refractory Hodgkin’s lymphoma (rrHL) who were given brentuximab vedotin (Adcetris) due to ineligibility for autologous stem cell transplant (ASCT). The study concluded that brentuximab vedotin is feasible and effective in patients with rrHL who are...

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Combined haploidentical-cord stem cell transplantation in lymphoma and CLL – what are the outcomes?

Posted by on Jan 30, 2018 in Hodgkin's lymphoma | 0 comments

In a nutshell This study analyzed the outcomes of lymphoma and chronic lymphoblastic leukemia (CLL) patients who received haplo-cord stem cell transplantation. The study concluded that this method gives higher rates of engraftment and lower rates of graft-versus-host disease (GVHD) compared to haploidentical transplant. Some background High-risk...

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