In a nutshell This study examined how often patients with Hodgkin lymphoma develop blood clots and what factors increase this risk. The results showed that a minority of patients develop blood clots and that there are several factors that increase the chance of blood clots developing. Some background Blood clots are more common in patients with...Read More
Hodgkin’s lymphoma Posts on Medivizor
In a nutshell This study looked at long-term outcomes of patients with early-stage Hodgkin lymphoma according to different treatments. It found that patients who received both radiation and chemotherapy had improved long-term survival compared to either treatment alone. Some background At present, over 90% of patients with classical Hodgkin lymphoma...Read More
How effective and safe is high-dose chemotherapy and stem cell transplant for children with lymphoma?
In a nutshell This study examined the effectiveness and safety of high-dose chemotherapy and stem cell transplants for children with lymphoma. The study showed that the combination treatment was very effective but that the dose may need to be adjusted for some patients. Some background Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL)...Read More
Does tumor size affect long-term outcomes after treatment for patients with early-stage Hodgkin lymphoma?
In a nutshell This study evaluated whether tumor size affected treatment outcomes for patients with early-stage (ES) Hodgkin lymphoma (HL). This study concluded that the risk of cancer recurrence increased with increasing tumor size. Some background PET scanning during treatment is used to guide therapy for patients with HL. Depending on the scan...Read More
In a nutshell This study reviewed treatment options for older patients newly diagnosed with classical Hodgkin lymphoma (cHL). It found that treatments including brentuximab vedotin (BV: Adcetris) are effective in this age group and that avoiding bleomycin (Blenoxane) prevents lung damage. Some background Around 20% of patients diagnosed with cHL...Read More
In a nutshell This review summarizes current treatment options of advanced classical Hodgkin lymphoma. It found that PET-scan based treatment minimizes long-term side effects and that both ABVD and eBEACOPP are useful chemotherapy regimens. Some background Classical Hodgkin lymphoma (cHL) is a cancer of white blood cells. If cancerous...Read More
In a nutshell This study evaluated the safety and effectiveness of brentuximab vedotin (Adcetris) in elderly patients with relapsed or unresponsive Hodgkin lymphoma (HL). This study found that this treatment was effective, although frail patients may be at higher risk for side effects. Some background Most patients with HL respond to front-line...Read More
In a nutshell This article reviews treatment options for patients with classical Hodgkin's lymphoma (cHL) that came back (relapsed) after chemotherapy. This study found that targeted therapies are becoming more prevalent and that patient outcomes have improved. Some background cHL is a cancer of white blood cells called lymphocytes....Read More
Have outcomes improved for patients with Hodgkin’s lymphoma who relapse after a stem cell transplant?
In a nutshell This study evaluated the long-term outcomes of patients with classical Hodgkin’s lymphoma (cHL) that came back after an autologous stem cell transplant (autoSCT). This study found that advancements in treatment have helped improve survival outcomes for patients. Some background Chemotherapy is usually the first-line...Read More
Evaluating brentuximab vedotin plus bendamustine for patients with hard-to-treat classical Hodgkin lymphoma
In a nutshell This study evaluated the effectiveness of brentuximab vedotin (Adcetris) plus bendamustine (Treanda) for patients with hard to treat classical Hodgkin lymphoma (cHL). This study found that this regimen is an effective salvage therapy for these patients. Some background Standard first-line chemotherapy is highly effective in treating...Read More
In a nutshell This study evaluated the outcomes of removing radiotherapy from treatment for patients with early-stage Hodgkin lymphoma (HL). This study concluded that radiotherapy improved survival without disease progression for patients while omitting it did not affect overall survival. Some background Chemotherapy followed by radiotherapy (RT)...Read More
In a nutshell This study evaluated the outcomes of a stem cell transplant after nivolumab (Opdivo) therapy in patients with classical Hodgkin’s lymphoma (cHL) that came back or stopped responding to treatment. This study concluded that nivolumab followed by stem cell transplant is safe and effective for these patients. Some background...Read More